M Kolak, J Westerbacka, VR Velagapudi, D Wågsäter, … - Diabetes, 2007 - Am Diabetes Assoc RESULTS— Expression levels of the macrophage marker CD68, the chemokines monocyte
chemoattractant protein-1 and macrophage inflammatory protein-1α, and plasminogen activator
inhibitor-1 were significantly increased, and those of peroxisome proliferator–activated ... Cited by 44 - Related articles - BL Direct - All 10 versions
J Makkonen, J Westerbacka, M Kolak, J Sutinen, … - International Journal of …, 2007 - nature.com To determine whether increased expression of macrophage markers and of inflammatory markers
in subcutaneous adipose tissue is associated with liver fat in human obesity. We also determined
whether expression of TNF (gene encoding TNF- ), HSD11B1 (gene encoding 11 ... Cited by 11 - Related articles - BL Direct - All 4 versions
- ►endojournals.org A Kotronen, J Westerbacka, R Bergholm, KH … - Journal of Clinical …, 2007 - Endocrine Soc Results: Liver fat was 4-fold higher in subjects with [n = 116; median 8.2% (interquartile range
3.2–18.7%)] than without [n = 155; 2.0% (1.0–5.0%); P < 0.0001] the metabolic syndrome. This
increase in liver fat remained significant after adjusting for age, gender, and body mass ... Cited by 50 - Related articles - BL Direct - All 3 versions
L Yetukuri, M Katajamaa, G Medina-Gomez, T … - BMC Systems …, 2007 - biomedcentral.com We present computational and informatics approaches to study lipid molecular profiles in the
context of known metabolic pathways and established pathophysiological responses, utilizing
information obtained from modern analytical technologies. In order to facilitate ... Cited by 46 - Related articles - Cached - All 16 versions
G Targher - Journal of hepatology, 2006 - Elsevier I read with interest the article by Haukeland et al. assessing the relationships between non-alcoholic
fatty liver disease (NAFLD) and plasma markers of inflammation in a small sample of patients
with biopsy-proven NAFLD [1]. They reported that NAFLD patients have significantly ... Cited by 15 - Related articles - All 15 versions
G Targher, L Bertolini, L Scala, G Zoppini, L Zenari, … - Diabetic …, 2005 - pt.wkhealth.com Results: Plasma hs-CRP, fibrinogen, v-WF and plasminogen activator inhibitor-1 (PAI-1) activity
levels were markedly higher (P < 0.01 or less) in subjects with non-alcoholic HS (n = 35) than
in those without HS (n = 65). The former also had significantly higher values for body ... Cited by 54 - Related articles - BL Direct - All 5 versions
A Rubio, E Guruceaga, M Vázquez-Chantada, J … - Journal of hepatology, 2007 - Elsevier We identified a gene-pathway associated with NASH, that accurately distinguishes between
patients with early-stage NASH and controls. Patients with steatosis have a gene expression
pattern intermediate between that of NASH and controls. Promoter analysis revealed that ... Cited by 15 - Related articles - All 13 versions
- ►ahajournals.org A Kotronen, H Yki-Jarvinen - Arteriosclerosis, Thrombosis, and …, 2008 - Am Heart Assoc Although the epidemic of obesity has been accompanied by an increase in the prevalence of
the metabolic syndrome, not all obese develop the syndrome and even lean individuals can
be insulin resistant. Both lean and obese insulin resistant individuals have an excess of ... Cited by 82 - Related articles - All 6 versions
JW Haukeland, JK Damås, Z Konopski, EM Løberg, T … - Journal of hepatology, 2006 - Elsevier Serum samples in 47 patients with histologically verified NAFLD (22 with simple steatosis and
25 with nonalcoholic steatohepatitis [NASH]), and in 30 age-, sex- and ethnicity-matched healthy
controls, were assessed for (i) general markers of inflammation (C-reactive protein [CRP], ... Cited by 99 - Related articles - All 11 versions
[CITATION] Insulin resistance atherosclerosis study. Elevations in markers of liver injury and …