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Scholar Results 1 - 10 of about 101 related to Doyle: Nkx2. 2 regulates β-cell function in the mature islet. (0.09 sec) 

Nkx2. 2 regulates β-cell function in the mature islet

- diabetesjournals.org
MJ Doyle, L Sussel - Diabetes, 2007 - Am Diabetes Assoc
Nkx2.2 is a homeodomain transcription factor that is critical for pancreatic endocrine cell
specification and differentiation in the developing mouse embryo. The purpose of this study was to
determine whether Nkx2.2 is also ...
Cited by 7 - Related articles - BL Direct - All 5 versions

Loss of Myt1 function partially compromises endocrine islet cell differentiation and …

- nih.gov
S Wang, J Zhang, A Zhao, S Hipkens, MA … - Mechanisms of …, 2007 - Elsevier
Myelin transcription factor 1 (Myt1) is one of the three vertebrate C2HC-type zinc finger
transcription factors that include Myt1 (Nzf1), Myt1L (Png1), and Myt3 (Nzf3, St18). All three
paralogs are widely expressed in ...
Cited by 4 - Related articles - All 4 versions

Stimulation of Human and Rat Islet {beta}-Cell Proliferation with Retention of …

- nih.gov
JC Schisler, PT Fueger, DA Babu, HE … - Molecular and cellular …, 2008 - Am Soc Microbiol
The homeodomain transcription factor Nkx6.1 plays an important role in pancreatic islet β-cell
development, but its effects on adult β-cell function, survival, and proliferation are not well
understood. In the present study, ...
Cited by 4 - Related articles - BL Direct - All 7 versions

Nkx2. 2-repressor activity is sufficient to specify {alpha}-cells and a small number of …

- biologists.org
MJ Doyle, ZL Loomis, L Sussel - Development, 2007 - dev.biologists.org
The homeodomain protein Nkx2.2 (Nkx2-2) is a key regulator of pancreatic islet cell specification in
mice; Nkx2.2 is essential for the differentiation of all insulin-producing ß-cells and of the
majority of glucagon-producing ...
Cited by 17 - Related articles - BL Direct - All 5 versions

The transcription factors Nkx6. 1 and Nkx6. 2 possess equivalent activities in …

- biologists.org
SB Nelson, AE Schaffer, M Sander - Development, 2007 - dev.biologists.org
Despite much progress in identifying transcriptional regulators that control the specification of
the different pancreatic endocrine cell types, the spatiotemporal aspects of endocrine subtype
specification have remained largely ...
Cited by 13 - Related articles - BL Direct - All 6 versions

Ptf1a and RBP-J cooperate in activating Pdx1 gene expression through binding to …


T Miyatsuka, T Matsuoka, T Shiraiwa, T Yamamoto, … - … and Biophysical Research …, 2007 - Elsevier
Pancreatic and duodenal homeobox factor 1 (Pdx1) has been demonstrated to play a crucial role in
pancreas development and in maintenance of mature β-cell function. However, it remains to be
elucidated how Pdx1 gene expression ...
Cited by 6 - Related articles - All 3 versions

The β-cell specific transcription factor Nkx6. 1 inhibits glucagon gene transcription …


BR Gauthier, Y Gosmain, A Mamin, J … - Biochemical …, 2007 - pubmedcentral.nih.gov
The transcription factor Nkx6.1 is required for the establishment of functional insulin-producing
β-cells in the endocrine pancreas. Overexpression of Nkx6.1 has been shown to inhibit glucagon gene
expression while favouring insulin ...
Cited by 7 - Related articles - BL Direct - All 5 versions

Efficient differentiation of insulin-producing cells from skin-derived stem cells


W Guo, C Miao, S Liu, Z Qiu, J Li, E Duan - Cell Proliferation, 2009 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to display style sheets. In
this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the ...
Related articles - All 4 versions

胰腺干细胞转分化为胰岛样细胞与天然胰岛细胞的基因差异性


李富荣 - 中国组织工程研究与临床康复, 2008 - cqvip.com
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中国组织工程研究与临床康复 >> 2008年12卷51期 >> 摘要. ...
Related articles - All 2 versions

Cooperative transcriptional regulation of the essential pancreatic islet gene …


KR Anderson, CA Torres, K Solomon, TC Becker, … - Journal of Biological …, 2009 - ASBMB
Nkx2.2 and NeuroD1 are two critical regulators of pancreatic β cell development. Nkx2.2 is a
homeodomain transcription factor that is essential for islet cell type specification and mature β
cell function. NeuroD1 is a basic ...
Related articles - All 3 versions


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