- ►diabetesjournals.org S Cabric, J Sanchez, T Lundgren, A Foss, M Felldin, R … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE—In clinical islet transplantation, the instant blood-mediated inflammatory reaction
(IBMIR) is a major factor contributing to the poor initial engraftment of the islets. This reaction
is triggered by tissue factor and monocyte chemoattractant protein (MCP)-1, expressed by ... Cited by 24 - Related articles - BL Direct - All 7 versions
S Cabric, G Elgue, B Nilsson, O Korsgren, P … - Cell Transplantation, …, 2006 - ingentaconnect.com Human islets induce an injurious clotting reaction at the time of transplantation. A potential strategy
to counteract this reaction would be to allow the islets to express hirudin, a protein with direct
anticoagulative activity. Human islets were transduced with an adenoviral vector ... Cited by 4 - Related articles - BL Direct - All 2 versions
- ►prsjournal.net E Rafael, A Tibell, M Ryden, T Lundgren, L … - American Journal of …, 2008 - prsjournal.net A 7-year-old girl with severe hereditary pancreatitis underwent total pancreatectomy. A total of
160 000 islet equivalents (6400 islet/kg) were transplanted to the brachioradialis muscle of the
right forearm. Her plasma C-peptide level was undetectable after pancreatectomy but ... Cited by 16 - Related articles - Cached - BL Direct - All 5 versions
H Johansson, M Goto, A Siegbahn, G … - American Journal of …, 2006 - interscience.wiley.com The instant blood-mediated inflammatory reaction (IBMIR) is triggered in clinical islet transplantation
when human pancreatic islets come in contact with blood and may explain the initial tissue loss
associated with this procedure. Low molecular weight dextran sulfate (LMW-DS; MM ... Cited by 29 - Related articles - BL Direct - All 4 versions
S Krol, S Del Guerra, M Grupillo, A Diaspro, A Gliozzi, P … - Nano Letters, 2006 - duke.edu Immune protection of artificial tissue by means of pancreatic islet microencapsulation is a very
ambitious new approach to avoid life-long immune suppression. But the success in the utilization
of the alginate-beads with incorporated islets is unfortunately limited. Some of the ... Cited by 14 - Related articles - View as HTML - All 5 versions
Y Teramura, Y Kaneda, T Totani, H Iwata - Biomaterials, 2008 - Elsevier We used three kinds of polymers that interact with living cells in different modes: poly(ethylene
glycol)–conjugated phospholipid (PEG–lipid) and poly(vinyl alcohol) carrying alkyl side chains
(PVA–alkyl), expected to anchor to the membrane lipid bilayer through hydrophobic ... Cited by 5 - Related articles - All 4 versions
T Kin, P Senior, D O'Gorman, B Richer, A Salam, AM … - Transpl Int, 2008 - interscience.wiley.com Culturing islets can add great flexibility to a clinical islet transplant program. However, a reduction
in the islet mass has been frequently observed during culture and its degree varies. The aim
of this study was to identify the risk factors associated with a significant islet loss during ... Cited by 6 - Related articles - All 4 versions
S Miura, Y Teramura, H Iwata - Biomaterials, 2006 - Elsevier The microencapsulation of islets of Langerhans (islets) has been studied as a safe and simple
technique for islet transplantation without the need for immuno-suppressive therapy.
However, thinner membranes are desired, because the increased total volume of the ... Cited by 16 - Related articles - All 6 versions
[CITATION] Heparin-binding to improve biocompatibility
