- ►diabetesjournals.org CQ Xia, R Peng, Y Qiu, M Annamalai, D … - Diabetes, 2007 - Am Diabetes Assoc In vivo induction of β-cell apoptosis has been demonstrated to be effective in
preventing type 1 diabetes in NOD mice. Based on the notion that steady-state
cell apoptosis is associated with self-tolerance and the need for ... Cited by 15 - Related articles - BL Direct - All 8 versions
P Saas, F Bonnefoy, S Kury-Paulin, F … - Transplantation, 2007 - journals.lww.com This work was supported by grants from the Association pour la Recherche sur le
Cancer (no. 3851), the Association pour la Recherche en Transfusion, and the
Etablissement Français du Sang (no. 2004.10). FB received financial ... Cited by 9 - Related articles - BL Direct - All 3 versions
- ►jimmunol.org J Unsinger, JM Herndon, CG Davis, JT … - The Journal of Immunology, 2006 - Am Assoc Immnol Sepsis induces extensive apoptosis in T and B cells suggesting that the loss of
immune effector cells could be one explanation for the profound
immunosuppression observed in this disorder. Unfortunately, the mechanisms ... Cited by 10 - Related articles - BL Direct - All 7 versions
CQ Xia, Y Qiu, RH Peng, J Lo-Dauer, MJ Clare … - Journal of Autoimmunity, 2008 - Elsevier Our previous study has demonstrated that transfusion of UVB-irradiation-induced
apoptotic β cells effectively prevents type 1 diabetes (T1D) in non-obese
diabetic (NOD) mice. However, the limitation of β cell source would ... Cited by 2 - Related articles - All 2 versions
- ►jbc.org AY Savinov, DV Rozanov, AY Strongin - Journal of Biological Chemistry, 2007 - ASBMB Human diabetes mellitus (IDDM; type I diabetes) is a T cell-mediated disease
that is closely modeled in non-obese diabetic (NOD) mice. The pathogenesis of
IDDM involves the transmigration of autoimmune T cells into the pancreatic ... Cited by 3 - Related articles - All 4 versions
EM Zeinstra, N Wilczak, JC Wilschut, L … - Journal of neuroimmunology, 2006 - Elsevier A failure of tight control of MHC class II expression on astrocytes may play a
role in the development of autoimmune responses in multiple sclerosis. The 5-HT
4 serotonin receptor agonists cisapride and prucalopride, at concentrations ... Cited by 4 - Related articles - All 10 versions
H Tsui, Y Chan, L Tang, S Winer, RK Cheung, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— pSC cultures did not express major histocompatibility complex (MHC)
class II and were lysed by ex vivo CTLs from diabetic NOD mice. In vivo,
restoration of MHC class I in GFAP-β2m transgenics significantly ... Cited by 4 - Related articles - BL Direct - All 4 versions
CD Sharp, M Huang, J Glawe, DR Patrick, S … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—TNF- significantly increased NOD/LtJ T-cell adhesion, which was
completely blocked by SDF-1 in a dose-dependent manner, revealing a novel
chemorepulsive effect. Conversely, SDF-1 enhanced C57BL/6J T-cell adhesion ... Cited by 4 - Related articles - BL Direct - All 4 versions
I Guleria, M Gubbels Bupp, S Dada, B Fife, Q … - Clinical Immunology, 2007 - Elsevier The PD-1–PDL1 pathway plays a critical role in regulating autoimmune diabetes
as blockade or deficiency of PD-1 or PDL1 results in accelerated disease in NOD
mice. We explored the cellular mechanisms involved in the regulation of ... Cited by 5 - Related articles - All 2 versions
D Yadav, C Fine, M Azuma, N Sarvetnick - Molecular immunology, 2007 - Elsevier Costimulation by B7-1 and B7-2 molecules results in divergent biological
effects. This is particularly striking in the NOD mouse, since the lack of B7-2
leads to complete protection from diabetes whereas the B7-1 deficiency ... Cited by 6 - Related articles - All 3 versions
