- ►diabetesjournals.org FGS Toledo, EV Menshikova, VB Ritov, K … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE— Reduced mitochondrial capacity in skeletal muscle occurs in type 2
diabetic patients and in those at increased risk for this disorder, but the
extent to which mitochondrial dysfunction in type 2 diabetic patients is ... Cited by 49 - Related articles - BL Direct - All 5 versions
FGS Toledo, EV Menshikova, K Azuma, Z … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE— In obesity and type 2 diabetes, exercise combined with weight loss
increases skeletal muscle mitochondrial capacity. It remains unclear whether
mitochondrial capacity increases because of weight loss, improvements in ... Cited by 20 - Related articles - BL Direct - All 5 versions
M Mogensen, K Sahlin, M Fernström, D … - Diabetes, 2007 - Am Diabetes Assoc We tested the hypothesis of a lower respiratory capacity per mitochondrion in
skeletal muscle of type 2 diabetic patients compared with obese subjects. Muscle
biopsies obtained from 10 obese type 2 diabetic and 8 obese nondiabetic ... Cited by 50 - Related articles - BL Direct - All 6 versions
- ►nih.gov R Boushel, E Gnaiger, P Schjerling, M … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Insulin resistance and type 2 diabetes are associated
with mitochondrial dysfunction. The aim of the present study was to test the
hypothesis that oxidative phosphorylation and electron transport capacity ... Cited by 80 - Related articles - BL Direct - All 9 versions
- ►endojournals.org FGS Toledo, S Watkins, DE Kelley - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc Objective: Our objective was to examine the effect of a lifestyle-modification
intervention on the content and morphology of skeletal muscle mitochondria and
its relationship to insulin sensitivity in obese, insulin-resistant subjects. Cited by 32 - Related articles - All 4 versions
- ►physiology.org EV Menshikova, VB Ritov, FGS Toledo, RE … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc The current study was undertaken to address responsiveness of skeletal muscle
mitochondrial electron transport chain (ETC) activity to weight loss (WL) and
exercise in overweight or obese, sedentary volunteers. Fourteen middle-aged ... Cited by 52 - Related articles - All 4 versions
DE Befroy, KF Petersen, S Dufour, GF Mason … - Diabetes, 2007 - Am Diabetes Assoc Insulin resistance is the best predictor for the development of diabetes in
offspring of type 2 diabetic patients, but the mechanism responsible for it
remains unknown. Recent studies have demonstrated increased ... Cited by 69 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org KS Nair, ML Bigelow, YW Asmann, LS Chow, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— The glucose infusion rates required to maintain identical glucose
levels during the similar insulin infusion rates were substantially lower in
diabetic Indians than in the nondiabetic participants (P < 0.001), and they ... Cited by 30 - Related articles - BL Direct - All 4 versions
C Bonnard, A Durand, S Peyrol, E Chanseaume … - The Journal of Clinical Investigation, 2008 - pubmedcentral.nih.gov Mitochondrial dysfunction in skeletal muscle has been implicated in the
development of type 2 diabetes. However, whether these changes are a cause or a
consequence of insulin resistance is not clear. We investigated the ... Cited by 53 - Related articles - BL Direct - All 8 versions
N Turner, CR Bruce, SM Beale, KL Hoehn, T … - Diabetes, 2007 - Am Diabetes Assoc A reduced capacity for mitochondrial fatty acid oxidation in skeletal muscle has
been proposed as a major factor leading to the accumulation of intramuscular
lipids and their subsequent deleterious effects on insulin action. Here, we ... Cited by 63 - Related articles - BL Direct - All 5 versions
