H Al-Kateb, L Mirea, X Xie, L Sun, M Liu, H Chen, SB … - Diabetes, 2007 - Am Diabetes Assoc RESULTS—In a global multi-SNP test, there was a highly significant association of VEGFA SNPs
with severe retinopathy (P = 6.8 × 10 −5 )—the four other outcomes were all nonsignificant. In
survival analyses controlling for covariate risk factors, eight SNPs showed significant ... Cited by 17 - Related articles - BL Direct - All 5 versions
- ►iovs.org AJ Churchill, JG Carter, C Ramsden, SJ Turner, A … - … Ophthalmology & Visual …, 2008 - ARVO RESULTS. Three of the promoter SNP genotypes, –160C, –152A (rs13207351), and –116A
(rs1570360), showed significant independent associations with PDR, as well as the minihaplotype
CAA (P = 0.00017). Two promoter haplotypes were associated with severity of ... Cited by 7 - Related articles - All 4 versions
- ►oxfordjournals.org M Buraczynska, P Ksiazek, I Baranowicz- … - Nephrology Dialysis …, 2006 - ERA-EDTA Results. The distribution of the VEGF DD genotype was significantly different in patients with
diabetic retinopathy compared with healthy controls, entire diabetic group and patients with no
complications (44 vs. 23, 30 and 21%, respectively; P < 0.01). Such differences were not ... Cited by 21 - Related articles - BL Direct - All 5 versions
H Al-Kateb, L Mirea, X Xie, L Sun, M Liu, H Chen - DIABETES, 2007 - Am Diabetes Assoc Page 1. Original Article Multiple Variants in Vascular Endothelial Growth Factor
(VEGFA) Are Risk Factors for Time to Severe Retinopathy in Type 1 Diabetes The
DCCT/EDIC Genetics Study Hussam Al-Kateb, 1 Lucia Mirea, 2 ... Related articles
A Paterson - Am Diabetes Assoc Page 1. Page 1 of 20 Multiple variants in Vascular Endothelial Growth Factor (VEGF) are risk factors
for time to severe retinopathy in type 1 diabetes: The DCCT/EDIC genetics study Received for
publication 19 March 2007 and accepted in revised form 1 May 2007. ... Related articles
AJ McKnight, AP Maxwell, CC Patterson, HR Brady, … - Journal of diabetes and its …, 2007 - Elsevier Vascular endothelial growth factor (VEGF) is reported to be implicated in the development of
diabetic nephropathy. We performed a case-control study to determine if VEGF-2578C→A,
VEGF-1499C→T, and VEGF-635G→C single-nucleotide polymorphisms (SNPs) in the ... Cited by 4 - Related articles - All 6 versions
DM Hallman, JC Huber, VH Gonzalez, BEK Klein, R … - Diabetes Care, 2005 - Am Diabetes Assoc RESULTS—Of 249 siblings of randomly selected probands with retinopathy, 169 (67.9%) had
retinopathy, compared with 95 of 125 siblings of unaffected probands (76.0%; P = 0.11). Proband
retinopathy class was associated (P = 0.03) with sibling retinopathy class, with significant ... Cited by 22 - Related articles - All 5 versions
DM Hallman, E Boerwinkle, VH Gonzalez, BEK Klein, R … - Diabetes, 2007 - Am Diabetes Assoc We conducted a genome-wide linkage scan for genes contributing to retinopathy risk using 794
diabetes case subjects from 393 Mexican-American families from Starr County, Texas, having
at least two diabetic siblings. The sample included 567 retinopathy case subjects ... Cited by 16 - Related articles - BL Direct - All 5 versions
HC Looker, RG Nelson, E Chew, R Klein, BEK Klein, … - Diabetes, 2007 - Am Diabetes Assoc Hyperglycemia and long duration of diabetes are widely recognized risk factors for diabetic
retinopathy, but inherited susceptibility may also play a role because retinopathy aggregates
in families. A genome-wide linkage analysis was conducted in 211 sibships in which ≥2 ... Cited by 16 - Related articles - BL Direct - All 10 versions
K Nakanishi, C Watanabe - Clinica Chimica Acta, 2009 - Elsevier Cumulative incidence of severe nonproliferative diabetic retinopathy (NPDR) differed among
genotypes in rs833070 and rs2146323, both of which located in intron 2. Homozygotes for the
minor alleles of rs833070, rs2146323, and rs699947, which were in strong linkage ... Cited by 1 - Related articles - All 2 versions
