L Logie, AJ Ruiz-Alcaraz, M Keane, YL Woods, J Bain, … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE—Abnormal expression of the hepatic gluconeogenic genes (glucose-6-phosphatase [G6Pase]
and PEPCK) contributes to hyperglycemia. These genes are repressed by insulin, but this process is
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- ►jbc.org CJ Green, O Goransson, GS Kular, NR Leslie, A … - Journal of Biological …, 2008 - ASBMB Protein kinase B (PKB)/Akt has been strongly implicated in the insulin-dependent stimulation of
GLUT4 translocation and glucose transport in skeletal muscle and fat cells. Recently an allosteric
inhibitor of PKB (Akti) that ... Cited by 9 - Related articles - All 3 versions
RW Hunter, MT Harper, I Hers - Journal of Thrombosis and …, 2008 - interscience.wiley.com Summary. Background: The role of PKB in platelet function is poorly defined due to the lack of
genuinely selective small-molecule inhibitors and limiting genetic models. Recently, a selective,
non-ATP-competitive PKB inhibitor, ... Cited by 2 - Related articles - All 3 versions
[CITATION] Adiponectin gene expressiio is inhibited by B—adrenergic stimulation via protein …
LIU Hai-Tao, Z Hai-Feng, SI Rui, Z Quan-Jiang, Z … - Acta Physiologica …, 2007 - actaps.com.cn Abstract: Our previous results have demonstrated that insulin reduces myocardial
ischemia/reperfusion (MI/R) injury and increases the postischemic myocardial functions via
activating the cellular survival ... Cited by 4 - Related articles - Cached - BL Direct - All 4 versions
J Guo, B Xiao, S Zhang, D Liu, Y Liao, Q … - Cancer biology & therapy, 2007 - ncbi.nlm.nih.gov Aloe-emodin is a novel active compound found in the root and rhizome of Rheum palmatum. To
investigate the effects and mechanisms of aloe-emodin on human gastric cancer, MGC-803 cells were
treated with 2.5, 5, 10, 20 and 40 ... Cited by 6 - Related articles - BL Direct - All 3 versions
SF Barnett, D Defeo-Jones, S Fu, PJ … - Biochemical …, 2005 - pubmedcentral.nih.gov We developed a high-throughput HTRF (homogeneous time-resolved fluorescence) assay for Akt kinase
activity and screened approx. 270000 compounds for their ability to inhibit the three isoforms of
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