- ►shouxi.net R Grempler, D Zibrova, C Schoelch, A van … - Diabetes, 2007 - Am Diabetes Assoc Type 2 diabetes is characterized by a progressive resistance of peripheral
tissues to insulin. Recent data have established the lipid phosphatase SH2
domain–containing inositol phosphatase 2 (SHIP2) as a critical negative ... Cited by 1 - Related articles - All 3 versions
R Grempler, D Zibrova, C Schoelch, A van … - DIABETES, 2007 - Am Diabetes Assoc Improvement of Glucose Tolerance by Liver-Specific ... SHIP2 Inhibition Causes
Insulin-Mimetic Effects on ... Rolf Grempler, 1 Darya Zibrova, 1 Corinna
Schoelch, 1 André van Marle, 2 Joerg F. Rippmann, 3 and Related articles
L Hansen, JN Jensen, CT Ekstrøm, H … - Diabetologia, 2001 - Springer Page 1. Impaired insulin-stimulated glycogen synthesis of skeletal muscle is
among the most consistent patho- physiological characteristics ... Cited by 6 - Related articles - BL Direct - All 3 versions
- ►endojournals.org S Guo, SL Dunn, MF White - Molecular Endocrinology, 2006 - Endocrine Soc The transcription factor FoxO1 links the phosphatidylinositol 3-kinase (PI
3-kinase) Akt cascade to gene expression that regulates cell growth, survival,
and metabolism. The receptors for insulin and IGFs factors are linked to ... Cited by 6 - Related articles - BL Direct - All 4 versions
T Sasaoka, K Fukui, T Wada, S Murakami, J … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 336–344 DOI 10.1007/s00125-004-1636-8 ARTICLE T.
Sasaoka . K. Fukui . T. Wada . S. Murakami . J. Kawahara . H. Ishihara . ... Cited by 8 - Related articles - All 2 versions
S Aiston, LJ Hampson, C Arden, PB Iynedjian, … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis: An insulin signalling pathway leading from activation
of protein kinase B (PKB, also known as Akt) to phosphorylation (inactivation)
of glyco- gen synthase kinase-3 (GSK-3) and activation of glycogen synthase ... Cited by 9 - Related articles - BL Direct - All 3 versions
M Ikubo, T Wada, K Fukui, M Ishiki, H … - American Journal of Physiology- Endocrinology And …, 2009 - Am Physiological Soc TNF- is a major contributor to the pathogenesis of insulin resistance associated
with obesity and inflammation by serine phosphorylating and degrading insulin
receptor substrate-1. Presently, we further found that pretreatment with ... Cited by 1 - Related articles - All 3 versions
- ►endojournals.org S Kagawa, T Sasaoka, S Yaguchi, H Ishihara, … - Journal of Clinical Endocrinology & Metabolism, 2005 - Endocrine Soc TYPE 2 (NONINSULIN DEPENDENT) diabetes mellitus is a disorder characterized by
insulin resistance in the target tissue of insulin with insufficient insulin
secretion in pancreatic ß-cells (1). The molecular mechanisms underlying ... Cited by 10 - Related articles - All 4 versions
- ►shouxi.net K Fukui, T Wada, S Kagawa, K Nagira, M … - Diabetes, 2005 - Am Diabetes Assoc We investigated the role of hepatic SH2-containing inositol 5′-phosphatase 2
(SHIP2) in glucose metabolism in mice. Adenoviral vectors encoding wild-type
SHIP2 (WT-SHIP2) and a dominant-negative SHIP2 (ΔIP-SHIP2) were injected ... Cited by 24 - Related articles - All 5 versions
R Grempler, S Leicht, I Kischel, P … - FEBS letters, 2007 - Elsevier Inhibition of the lipid phosphatase SH2-domain containing inositol phosphatase 2
(SHIP2) in L6-C10 muscle cells, in 3T3-L1 adipocytes and in the liver of db/db
mice has been shown to ameliorate insulin signal transduction and ... Cited by 3 - Related articles - All 3 versions
