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Bone marrow is a preferential homing site for autoreactive T-cells in type 1 diabetes

- diabetesjournals.org
R Li, N Perez, S Karumuthil-Melethil, C Vasu - Diabetes, 2007 - Am Diabetes Assoc
OBJECTIVE—The pancreatic microenvironment is considered to be the primary
location of autoreactive T-cells in type 1 diabetes. Diabetogenic T-cells have
also been detected in the spleens of NOD mice. However, it is not known ...
Cited by 8 - Related articles - BL Direct - All 4 versions

[CITATION] Autologous bone marrow mononuclear cell (ABMMC) transplantation in type 1 and type 2 …


J Tuma-Mubarak, R Fernandez-Viña, AC … - Links
Cited by 2 - Related articles

Elevated CXCL 12 expression in the bone marrow of NOD mice is associated with altered T …


Q Leng, Y Nie, Y Zou, J Chen - BMC immunology, 2008 - biomedcentral.com
Type I diabetes (TID) is an autoimmune disease resulting from destruction of the
insulin-producing β-cells by autoreactive T cells. Studies have shown that
polymorphisms of chemokine CXCL12 gene are linked to TID in humans. In ...
Cited by 2 - Related articles - Cached - All 6 versions

[CITATION] Insulin requeirements, HbA1c, and stimulated C-peptide following autologous umbilical cord …


MJ Haller, H Viener, T Brusko, C Wasserfall, K … - Links
Cited by 2 - Related articles

[PDF] A perspective on stem cells by a clinician


IA Hughes - European journal of endocrinology, 2004 - EFES
Stem cell terminology has entered the lexicon of medical practitioners even
though the application of harvesting stem cells to treat diseases other than
haematological disorders is not yet a reality in clini- cal practice. All ...
Cited by 5 - Related articles - BL Direct - All 11 versions

Transfer of autoimmune diabetes from diabetic NOD mice to NOD athymic nude mice: the roles …


M Matsumoto, H Yagi, K Kunimoto, J … - Cellular immunology, 1993 - ncbi.nlm.nih.gov
The NOD mouse, which spontaneously develops insulitis and overt diabetes, is a
model of autoimmune type I diabetes mellitus. To analyze of the roles of CD4+
and CD8+ T cells in the pathogenesis of this mouse, we have been doing a ...
Cited by 14 - Related articles - BL Direct - All 2 versions

Endovenous Administration of Bone Marrow-Derived Multipotent Mesenchymal Stromal Cells …


F Ezquer, M Ezquer, V Simon, F Pardo, A … - Biology of Blood and Marrow Transplantation, 2009 - Elsevier
Twenty-five to 40% of diabetic patients develop diabetic nephropathy, a clinical
syndrome that comprises renal failure and increased risk of cardiovascular
disease. It represents the major cause of chronic kidney disease and is ...
Related articles - All 4 versions

Immune dysregulation and dyserythropoiesis in the myelodysplastic syndromes


F Alfinito, M Sica, L Luciano, R Della Pepa, C … - British Journal of Haematology, 2009 - interscience.wiley.com
The myelodysplastic syndromes (MDS) are clonal disorders characterised by
ineffective haematopoiesis with high risk of leukaemia progression. The
relevance of immune-dysregulation for emergence, dominance and progression ...
Related articles - All 2 versions

Medicina Regenerativa en Cuba


CEB Couri, JC Voltarelli - sld.cu
Type 1 diabetes mellitus is the result of the autoimmune response against
pancreatic b-cell(s). At the time of clinical diagnosis near 70% of b-cell mass
is been destroyed as a consequence of the auto-destruction that begins ...
Related articles - Cached

[CITATION] Antihypertensive agents for prevention of diabetic nephropathy.


RL Dressler - American family physician, 2006 - ncbi.nlm.nih.gov
1: Am Fam Physician. 2006 Jul 1;74(1):77-9. Antihypertensive agents for
prevention of diabetic nephropathy. Dressler RL. University ...
Cited by 1 - Related articles


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