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Normal Relationship of β-and Non–β-Cells Not Needed for Successful Islet Transplantation

- shouxi.net
AJF King, JR Fernandes, J Hollister-Lock, CE … - Diabetes, 2007 - Am Diabetes Assoc
Islets are composed mostly of β-cells, and therefore stem cell research has
concentrated on generating purified β-cells, neglecting the other endocrine
cell types in the islet. We investigated the presence of endocrine non–β- ...
Cited by 8 - Related articles - BL Direct - All 4 versions

Normal relationship of beta and non-beta cells not needed for successful islet transplantation …


AJFK PhD, JR Fernandes, J Hollister-Lock, … - Am Diabetes Assoc
Aileen JF King PhD 1,2,*, Justin R. Fernandes BA 1*, Jennifer Hollister-Lock BA
1, Cameron E. Nienaber BA 1, Susan Bonner-Weir PhD1, Gordon C. Weir MD 1. ...
Running title: Transplantation of purified beta cells.
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Glucagon expression shift in a syngeneic single-donor intrahepatic rat islet transplantation …


L Günther, X Liu, H Neeff, O Drognitz, UT Hopt - Transplantation proceedings, 2005 - Elsevier
In the native rat pancreas glucagon is expressed by α cells in the outer layer
of the spheroid islet, producing a circular immunohistochemical staining
pattern. We asked whether this pattern would remain unchanged after ...
Cited by 4 - Related articles - All 9 versions

Features of the morphofunctional state of the endocrine part of the pancreas during the …


TA Shubina, AM Ul'yanov - Moscow University Biological Sciences Bulletin, 2009 - Springer
The wide spread occurrence of insulindependent diabetes (diabetes mellitus, DM)
determines the necessity to develop new approaches to the prevention and cure of
this pathology and its complications. A large number of studies testify ...
Related articles - All 2 versions

糖尿病的实用治疗 β 细胞的修复


郭庆畲 - 医学综述, 2008 - cqvip.com
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Evaluation of insulin secretion by in vitro generated human islet-like clusters

- ubc.ca [PDF] 
YH Liao - circle.ubc.ca
Page 1. EVALUATION OF INSULIN SECRETION BY IN VITRO GENERATED HUMAN ISLET-LIKE
CLUSTERS by Yu Huan Liao B.Sc., Biochemistry, University ...
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Islet alpha cell number is maintained in microencapsulated islet transplantation


S Bohman, AJF King - Biochemical and Biophysical Research …, 2008 - Elsevier
Islet transplantation can reverse hyperglycaemia in Type 1 diabetes patients.
One problem in islet transplantation is a loss of beta cell mass as well as
blunted glucagon responses from the grafted islets. It has been suggested ...
Cited by 1 - Related articles - All 3 versions

Pancreatic Islet Transplantation and Regeneration for Diabetes mellitus Treatment


D Babarykin, V Nikolajeva, D Eze, D Amerika - Proceedings of the Latvian Academy of Sciences. …, 2008 - Versita
The pancreas contains exocrine, endocrine, and ductal cells and serves two major
functions: (a) the production of diges- tive enzymes, such as amylase and
lipase, which are se- creted by exocrine acinar cells and routed to the ...
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[PDF] Eliminating Oxygen Supply Limitations for Transplanted Microencapsulated Islets in the …


AS Lewis, 2008 - dspace.mit.edu
Page 1. 1 ELIMINATING OXYGEN SUPPLY LIMITATIONS FOR TRANSPLANTED MICROENCAPSULATED
ISLETS IN THE TREATMENT OF TYPE I DIABETES by Amy Suzanne Lewis ...
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Generation of insulin-secreting cells from pancreatic acinar cells of animal models of type 1 …

- physiology.org
M Okuno, K Minami, A Okumachi, K Miyawaki, … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc
We recently found that pancreatic acinar cells isolated from normal adult mouse
can transdifferentiate into insulin-secreting cells in vitro. Using two
different animal models of type 1 diabetes, we show here that ...
Cited by 11 - Related articles - BL Direct - All 6 versions


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