- ►angrylapdog.com MA Croce, JC Eagon, LL LaRiviere, KM … - …, 2007 - diabetes.diabetesjournals.org.p. … RESULTS— The expression of lipin 1β in liver and adipose tissue was inversely related to
BMI, fasting plasma insulin concentration, and the homeostasis model assessment of insulin
resistance but was significantly increased by marked weight loss and insulin sensitization ... Cited by 13 - Related articles - BL Direct - All 5 versions
- ►endojournals.org J Donkor, LM Sparks, H Xie, SR Smith, K … - Journal of Clinical …, 2008 - Endocrine Soc Results: In healthy young men, lipin-1 expression was positively correlated with insulin sensitivity
(R 2 = 0.22; P < 0.01), insulin-stimulated respiratory quotient (R 2 = 0.16; P < 0.01), and maximal
oxygen consumption during exercise (R 2 = 0.16; P < 0.01). Lipin-1 mRNA levels were ... Cited by 8 - Related articles - BL Direct - All 6 versions
KA Fawcett, N Grimsey, RJF Loos, E Wheeler, A Daly, … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE— Loss of lipin 1 activity causes lipodystrophy and insulin resistance in the fld
mouse, and LPIN1 expression and common genetic variation were recently suggested to influence
adiposity and insulin sensitivity in humans. We aimed to conduct a comprehensive ... Cited by 3 - Related articles - All 6 versions
RJF Loos, T Rankinen, L Pérusse, A Tremblay, JP … - Obesity, 2007 - nature.com Results: The strongest results were generation-specific. In parents, RMR of the G/G IVS13 +
3333A>G homozygotes was 107 kcal/d higher than in A/A homozygotes and 39 kcal/d higher
than in A/G heterozygotes (p = 0.0003). In offspring, carriers of the C allele of the IVS18 + ... Cited by 8 - Related articles - All 3 versions
- ►endojournals.org [PDF] J Donkor, LM Sparks, H Xie, SR Smith, K … - Journal of Clinical …, 2007 - Endocrine Soc Page 1. 1 Adipose tissue lipin-1 expression is correlated with PPARα gene expression
and insulin sensitivity in healthy young men a Jimmy Donkor 1 , Lauren M. Sparks 2 ,
Hui Xie 2 , Steven R. Smith 2 , Karen Reue 1 1 Departments ... Cited by 4 - Related articles
S Wiedmann, M Fischer, M Koehler, K Neureuther, G … - Diabetes, 2008 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS— A total of 15 single nucleotide polymorphisms
(SNPs) covering the LPIN1 gene region were genotyped in an age- and sex-stratified sample
of the general population (Monitoring Trends and Determinants on Cardiovascular ... Cited by 10 - Related articles - BL Direct - All 4 versions
- ►ahajournals.org Z Chen, MC Gropler, J Norris, JC Lawrence Jr … - … , and vascular biology, 2008 - Am Heart Assoc Methods and Results— Rates of TAG synthesis were not impaired in hepatocytes isolated from
adult lipin 1–deficient (fld) mice and were actually increased in 14-day-old fld mice.
Additionally, compared to littermate controls, VLDL-TAG secretion rates were markedly ... Cited by 6 - Related articles - All 8 versions
B Lindegaard, LF Larsen, ABE Hansen, J Gerstoft … - International Journal of …, 2006 - nature.com Lipodystrophy is the major complication of antiretroviral therapy in HIV-infected patients. Its pathophysiology
is not well understood, but has been linked to antiadipogenic effects of antiretroviral drugs. Lipin
represents a newly characterized protein that is critical for adipocyte differentiation, and ... Cited by 16 - Related articles - BL Direct - All 4 versions
- ►jlr.org V van Harmelen, M Ryden, E Sjolin, J Hoffstedt - The Journal of Lipid Research, 2007 - ASBMB The mouse lipin gene, Lpin1, is important for adipose tissue development and is a candidate
gene for insulin resistance. Here, we investigate the adipose tissue expression levels of the human
LPIN1 gene in relation to various clinical variables as well as adipocyte function. LPIN1 ... Cited by 26 - Related articles - All 4 versions
- ►angrylapdog.com TE Harris, TA Huffman, A Chi, J … - Journal of …, 2007 - jbc.org.p.angrylapdog.com Brain, liver, kidney, heart, and skeletal muscle from fatty liver dystrophy (fld/fld) mice, which do
not express lipin 1 (lipin), contained much less Mg 2+ -dependent phosphatidic acid phosphatase
(PAP) activity than tissues from wild type mice. Lipin harboring the fld 2j (Gly 84 Arg) ... Cited by 34 - Related articles - All 8 versions
