- ►shouxi.net E Riedl, H Koeppel, P Brinkkoetter, P Sternik … - Diabetes, 2007 - Am Diabetes Assoc Recently, we demonstrated that a polymorphism in exon 2 of the serum carnosinase
(CNDP1) gene is associated with susceptibility to developing diabetic
nephropathy. Based on the number of CTG repeats in the signal peptide, five ... Cited by 7 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org K Wanic, G Placha, J Dunn, A Smiles, JH … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVES— Recently, an association was found between diabetic nephropathy
and the D18S880 microsatellite, located in the carnosinase gene (CNDP1) on
chromosome 18q. Alleles of this microsatellite encode for a variable number ... Cited by 3 - Related articles - All 3 versions
CW McDonough, PJ Hicks, L Lu, CD … - Human Genetics, 2009 - Springer Abstract Four genome wide linkage scans for diabetic nephropathy have mapped
susceptibility loci to chromo- some 18q22.3-23 in the region of the carnosinase
genes, CNDP1 and CNDP2. CNDP1 has been associated with dia- betic ... Cited by 4 - Related articles
G Mannheim - Am Diabetes Assoc Riedl E1* and Koeppel H1*, Brinkkoetter P1, Sternik P1, Steinbeisser H2,
Sauerhoefer S1, Janssen B2, van der Woude FJ1†, Yard BA1 * Equally
contributing authors ... From the departments of: 1 Department of ... Related articles
- ►oxfordjournals.org BI Freedman, PJ Hicks, MM Sale, ED Pierson … - Nephrology Dialysis Transplantation, 2007 - ERA-EDTA Background. Four linkage analyses have identified a region on chromosome
18q22-23 that appears to harbour a diabetic nephropathy (DN) susceptibility
locus. A trinucleotide repeat sequence in exon 2 of the carnosinase gene ... Cited by 32 - Related articles - BL Direct - All 4 versions
S Sauerhöfer, G Yuan, GS Braun, M Deinzer, … - Diabetes, 2007 - Am Diabetes Assoc RESULTS—Fasting plasma glucose as well as A1C levels rose significantly
earlier and remained higher in transgenic animals throughout life. Body weights
were reduced as a result of significant glucosuria. In an opposite ... Cited by 12 - Related articles - BL Direct - All 3 versions
AL Mooyaart, IGM van Valkengoed, PKC Shaw, … - Diabetes Research and Clinical Practice, 2009 - Elsevier We investigated the frequency of the 5/5 homozygous CNDP1 (carnosinase)
genotype, which was found to be associated with a reduced risk of developing
diabetic nephropathy, in three ethnic groups in The Netherlands. ... Related articles - All 5 versions
J Divers, BI Freedman - Hypertension, 2009 - pdfs.journals.lww.com Introduction Improvements in genotyping, computing and statistical analysis now
make it possible to scan the entire genome using single-nucleotide polymorphisms
(SNPs), and apply novel methods such as mapping by admixture linkage ... Related articles - All 4 versions
A Shimazaki, Y Tanaka, T Shinosaki, M Ikeda … - Kidney international, 2006 - nature.com We have previously identified the engulfment and cell motility 1 (ELMO1) as a
susceptibility gene for diabetic nephropathy. To elucidate the role of ELMO1 in
the pathogenesis of chronic renal injury, we examined the expression of ... Cited by 7 - Related articles - BL Direct - All 4 versions
W Ju, F Eichinger, M Bitzer, J Oh, S … - American Journal of Pathology, 2009 - ASIP Although chronic kidney disease (CKD) is common, only a fraction of CKD patients
progress to end-stage renal disease. Molecular predictors to stratify CKD
populations according to their risk of progression remain undiscovered. ... Cited by 1 - Related articles - All 3 versions
