CD Sharp, M Huang, J Glawe, DR Patrick, S Pardue, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—TNF- significantly increased NOD/LtJ T-cell adhesion, which was completely blocked
by SDF-1 in a dose-dependent manner, revealing a novel chemorepulsive effect.
Conversely, SDF-1 enhanced C57BL/6J T-cell adhesion to TNF- –activated islet ... Cited by 4 - Related articles - BL Direct - All 4 versions
- ►jbc.org AY Savinov, DV Rozanov, AY Strongin - Journal of Biological Chemistry, 2007 - ASBMB Human diabetes mellitus (IDDM; type I diabetes) is a T cell-mediated disease that is closely modeled
in non-obese diabetic (NOD) mice. The pathogenesis of IDDM involves the transmigration of
autoimmune T cells into the pancreatic islets and the subsequent destruction of insulin- ... Cited by 3 - Related articles - All 4 versions
EM Zeinstra, N Wilczak, JC Wilschut, L Glazenburg, … - Journal of …, 2006 - Elsevier A failure of tight control of MHC class II expression on astrocytes may play a role in the development
of autoimmune responses in multiple sclerosis. The 5-HT 4 serotonin receptor agonists cisapride
and prucalopride, at concentrations between 10 − 10 M and 10 − 8 M, reduced ... Cited by 4 - Related articles - All 10 versions
H Tsui, Y Chan, L Tang, S Winer, RK Cheung, G … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— pSC cultures did not express major histocompatibility complex (MHC) class II and
were lysed by ex vivo CTLs from diabetic NOD mice. In vivo, restoration of MHC class I in
GFAP-β2m transgenics significantly accelerated adoptively transferred diabetes. Target ... Cited by 4 - Related articles - BL Direct - All 4 versions
I Guleria, M Gubbels Bupp, S Dada, B Fife, Q Tang, MJ … - Clinical Immunology, 2007 - Elsevier The PD-1–PDL1 pathway plays a critical role in regulating autoimmune diabetes as blockade
or deficiency of PD-1 or PDL1 results in accelerated disease in NOD mice. We explored the cellular
mechanisms involved in the regulation of these autoimmune responses by investigations ... Cited by 5 - Related articles - All 2 versions
D Yadav, C Fine, M Azuma, N Sarvetnick - Molecular immunology, 2007 - Elsevier Costimulation by B7-1 and B7-2 molecules results in divergent biological effects. This is particularly
striking in the NOD mouse, since the lack of B7-2 leads to complete protection from diabetes
whereas the B7-1 deficiency causes exacerbation of disease. We tested the hypothesis ... Cited by 6 - Related articles - All 3 versions
- ►diabetesjournals.org [PDF] S Klinger, C Poussin, MB Debril, W Dolci, PA Halban, B … - Diabetes, 2007 - Am Diabetes Assoc 1 Institute of Physiology, 2 Center for Integrative Genomics, University of Lausanne, 1015
Lausanne, Switzerland, 3 Department of Genetic Medicine and Development, University Medical
Center, University Hospital, 1211 Geneva 4, Switzerland ... Running title: Increasing ... Cited by 1 - Related articles - All 2 versions
M Kagami-Takasugi, N Katsumata, T Tanaka, … - Journal of pediatric …, 2006 - ncbi.nlm.nih.gov We analyzed 84 Japanese patients with juvenile-onset (before 18 years of age) non-obese diabetes
mellitus (DM) for mutations in the genes for HNF-1alpha, HNF-4alpha and HNF-1beta. In
HNF-1alpha, previously reported mutations (R271W and R272C) and one novel ... Cited by 1 - Related articles - BL Direct - All 2 versions
T Shigihara, A Shimada, S Yamada, T … - ANNALS-NEW …, 2003 - interscience.wiley.com Abstract: Type 1 diabetes is characterized by cell-mediated autoimmune destruction of pancreatic
beta cells. Although the disease shows a strong association with HLA class II alleles, other genes
may influence the initiation or the rate of progression of the autoimmune process. ... Cited by 1 - Related articles - BL Direct - All 5 versions
T Saito, K Tojo, G Kuriyama, Y Murakawa, K … - ENDOCRINE …, 2004 - pathology2.jhu.edu Abstract. A 75-year-old male showed combined anterior pituitary hormone deficiency
(CPHD). Basal and TRH- stimulated PRL levels were undetectable. Basal and GRH-stimulated
GH levels were very low, and could barely be measured by means of an ultrasensitive ... Cited by 1 - Related articles - BL Direct - All 4 versions
