BA Menge, A Tannapfel, O Belyaev, R Drescher … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Protocol 1: fasting glucose concentrations increased significantly
after the 50% pancreatectomy (P = 0.01), but the fractional β-cell area of the
pancreas remained unchanged (P = 0.11). β-Cell proliferation, the overall ... Cited by 24 - Related articles - BL Direct - All 5 versions
BA Menge, H Schrader, TGK Breuer, Y … - Diabetologia, 2009 - Springer Abstract Aims/hypothesis Partial pancreatectomy is frequently per- formed in
patients with pancreatic tumours or chronic pancreatitis, but little is known
about the metabolic impact of this intervention. We examined the effects of ... Cited by 3 - Related articles - All 2 versions
M Peshavaria, BL Larmie, J Lausier, B Satish, … - Diabetes, 2006 - Am Diabetes Assoc The pancreatic β-cell has a substantial capacity to functionally compensate in
response to physiological and pathophysiological changes in tissue insulin
requirements. A fundamental aspect of this response is the dynamic ... Cited by 24 - Related articles - BL Direct - All 5 versions
AE Butler, A Huang, PN Rao, A Bhushan, WJ … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE—Type 1 and type 2 diabetes are characterized by an ∼98 and ∼65%
loss of pancreatic β-cells, respectively. Efforts to reverse either form of
diabetes increasingly focus on the possibility of promoting β-cell ... Cited by 17 - Related articles - BL Direct - All 6 versions
BA Menge - www-brs.ub.ruhr-uni-bochum.de Page 1. Aus der Medizinischen Klinik I des St. Josef-Hospitals Bochum -
Universitätsklinik - der Ruhr-Universität Bochum Direktor: Prof. Dr. med. ... Related articles
J Rahier, Y Guiot, RM Goebbels, C Sempoux, … - Diabetes Obes Metab, 2008 - interscience.wiley.com Decreases in both β-cell function and number can contribute to insulin
deficiency in type 2 diabetes. Here, we quantified the β-cell mass in pancreas
obtained at autopsy of 57 type 2 diabetic (T2D) and 52 non-diabetic ... Cited by 10 - Related articles - All 2 versions
PC Butler, JJ Meier, AE Butler, A Bhushan - Nature clinical practice. Endocrinology & metabolism, 2007 - ncbi.nlm.nih.gov Replication of beta cells is an important source of beta-cell expansion in early
childhood. The recent linkage of type 2 diabetes with several transcription
factors involved in cell cycle regulation implies that growth of the ... Cited by 42 - Related articles - BL Direct - All 3 versions
AV Matveyenko, JD Veldhuis, PC Butler - Diabetes, 2006 - Am Diabetes Assoc Impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) often
coexist and as such represent a potent risk factor for subsequent development of
type 2 diabetes. β-Cell mass is ∼50% deficient in IFG and ∼65% ... Cited by 22 - Related articles - BL Direct - All 6 versions
JJ Meier, AE Butler, R Galasso, RA Rizza, PC … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis Type 1 and type 2 diabetes are charac- terised by a
beta cell deficit. Islet hyperplasia has been described in patients with
Zollinger–Ellison syndrome secondary to gastrin-producing tumours ... Cited by 21 - Related articles - BL Direct - All 5 versions
JJ Meier, AE Butler, Y Saisho, T Monchamp, … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE— Little is known about the capacity, mechanisms, or timing of growth
in β-cell mass in humans. We sought to establish if the predominant expansion
of β-cell mass in humans occurs in early childhood and if, as in rodents, ... Cited by 23 - Related articles - All 3 versions
