- ►diabetesjournals.org ML Onozato, A Tojo, J Leiper, T Fujita, F Palm, CS … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Immunostaining and Western blotting of microdissected nephron segments localized
DDAH I in the proximal tubules and DDAH II in the glomeruli, afferent arterioles, macula
densa, and distal nephron. Renal Ang II and S ADMA increased with diabetes but were ... Cited by 7 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org [PDF] ML Onozato, A Tojo, J Leiper, T Fujita, F Palm, CS … - Diabetes, 2007 - Am Diabetes Assoc 1 Maristela L. Onozato, 1 Akihiro Tojo, 3 James Leiper, 1 Toshiro Fujita, 2 Frederik Palm and
2 Christopher S. Wilcox ... 1 Division of Nephrology and Endocrinology, University of Tokyo,
Tokyo, Japan; ... Division of Nephrology and Hypertension, Cardiovascular Kidney ... Cited by 3 - Related articles - All 2 versions
- ►ahajournals.org F Scalera, J Martens-Lobenhoffer, A Bukowska, U … - Hypertension, 2008 - Am Heart Assoc Telmisartan, in addition to blocking angiotensin (Ang) II type 1 receptor (AT 1 R), activates peroxisome
proliferator activated receptor (PPAR ) signaling that interferes with nitric oxide (NO) system.
Because aging of endothelial cells (ECs) is hallmarked by a reduction in NO synthesis, ... Cited by 11 - Related articles - All 5 versions
- ►jbc.org L Hong, W Fast - Journal of Biological Chemistry, 2007 - ASBMB The plasma concentrations of two cardiovascular risk factors, total homocysteine (tHcy) and asymmetric
dimethylarginine (ADMA), correlate with decreased levels of endothelium-derived nitric oxide
and subsequent endothelial dysfunction. Homocysteine has been proposed to inhibit the ... Cited by 5 - Related articles - All 4 versions
- ►ahajournals.org Z Veresh, A Racz, G Lotz, A Koller - Hypertension, 2008 - Am Heart Assoc Asymmetrical dimethylarginine (ADMA) is thought to be an endogenous regulator of arteriolar
tone by inhibiting NO synthase. However, our previous studies showed that, in isolated
arterioles, ADMA induced superoxide production as well. Thus, the mechanisms by which ... Cited by 6 - Related articles - All 8 versions
DTM Ngo, AL Sverdlov, JJ McNeil, JD Horowitz - Pharmacological Research, 2009 - Elsevier A number of previous investigators have demonstrated that arterial augmentation index
(AIx), a measure of apparent arterial stiffness, reflects in part vascular endothelial function, and
that AIx is modulated by nitric oxide (NO) responses. We evaluated AIx in a population of ... Related articles - All 2 versions
AJ Pope, K Karrupiah, PN Kearns, Y Xia, AJ … - Journal of Biological …, 2009 - ASBMB Reduced NO is a hallmark of endothelial dysfunction and among the mechanisms for impaired
NO synthesis is the accumulation of the endogenous NOS inhibitor asymmetric dimethylarginine
(ADMA). Free ADMA is actively metabolized by the intracellular enzyme dimethylarginine ... Related articles - All 2 versions
M Sharma, Z Zou, H Miura, A … - American Journal of …, 2009 - Am Physiological Soc Page 1. 1 ADMA Injures the Glomerular Filtration Barrier: Role of Nitric Oxide and Superoxide
Authors Mukut Sharma1, Zongmin Zou2, Hiroto Miura3, Andreas Papapetropoulos2, Ellen T.
McCarthy4, Ram Sharma5, Virginia J. Savin1, Elias A. Lianos2 Affiliation ... Related articles - All 3 versions
C Wadham, AA Mangoni - Expert Opin. Drug Metab. Toxicol., 2009 - Informa Pharma Science Asymmetric dimethylarginine (ADMA), an endogenous methylated form of the amino acid
l-arginine, inhibits the activity of the enzyme endothelial nitric oxide synthase, with consequent
reduced synthesis of nitric oxide. ADMA is metabolised to l-citrulline and dimethylamine ... Related articles - All 4 versions
