M Zoledziewska, C Perra, V Orrù, L Moi, P … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— The +1858C>T variant, albeit rare in the general Sardinian population
(allele frequency 0.014), was positively associated with type 1 diabetes (P one
tail = 3.7 × 10 −3 ). In contrast, the background haplotype in which ... Cited by 9 - Related articles - BL Direct - All 3 versions
[CITATION] ME;, Balding DJ (2003) Inferences from DNA data: population histories, evolutionary …
MG Marrosu, R Murru, G Costa, MC Melis, M … - BMC genetics, 2007 - biomedcentral.com Multiple sclerosis (MS) is consistently associated with particular HLA-DRB1-DQB1
haplotypes. However, existing evidence suggests that variation at these loci
does not entirely explain association of the HLA region with the disease. ... Cited by 4 - Related articles - Cached - All 8 versions
JM McPartland, RW Norris, CW Kilpatrick - Journal of Molecular Evolution, 2007 - Springer Abstract The best-known endocannabinoid ligands, anandamide and 2-AG, signal at
least seven receptors and involve ten metabolic enzymes. Genes for the receptors
and enzymes were examined for heterogeneities in tempo (relative rate of ... Cited by 6 - Related articles - BL Direct - All 2 versions
K Saito, S Williams, A Bulankina, S Honing, T … - Journal of Biological Chemistry, 2007 - ASBMB The protein-tyrosine phosphatase PTPMEG2 is located on the cytoplasmic face of
the enclosing membrane of secretory vesicles, where it regulates vesicle size by
promoting homotypic vesicle fusion by dephosphorylating N-ethylmaleimide- ... Cited by 6 - Related articles - All 5 versions
B Skinningsrud, ES Husebye, K Gervin, K … - European Journal of Human Genetics, 2008 - nature.com The tyrosine-protein phosphatase non-receptor type 22 (PTPN22) gene was recently
identified as an important genetic susceptibility factor in several autoimmune
diseases. The increased risk has been broadly explained by the 1858T-allele ... Cited by 15 - Related articles - All 3 versions
[CITATION] 8. Paleolithic Sardinians: Paleontological Evidence and Methods
L Chatenoud - International reviews of immunology, 2006 - informahealthcare.com Currently, therapies applied in transplantation and autoimmunity are essentially
based on the use of immunosuppressants. These agents depress all immune
responses and expose individuals to the recurrence of the pathogenic immune ... Cited by 10 - Related articles - BL Direct - All 6 versions
D Contu, L Morelli, F Santoni, JW Foster, P …, 2008 - eprints.uniss.it The island of Sardinia shows a unique high incidence of several autoimmune
diseases with multifactorial inheritance, particularly type 1 diabetes and
multiple sclerosis. The prior knowledge of the genetic structure of this ... Related articles - View as HTML - All 2 versions
