- ►diabetesjournals.org M Vaxillaire, J Veslot, C Dina, C Proença, S Cauchi, G … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— The GCK (Glucokinase) −30A allele was associated with increased type 2 diabetes
risk at the end of the follow-up study (adjusted OR 1.34 [95% CI 1.07–1.69]) under an additive
model, as supported in independent French diabetic case subjects (OR 1.22, P = 0.007), ... Cited by 34 - Related articles - BL Direct - All 4 versions
MV PharmD, J Veslot, C Dina, C Proença, SC PhD, G … - Am Diabetes Assoc Page 1. Impact of Common Type 2 Diabetes Risk Polymorphisms in the DESIR
Prospective Study Martine Vaxillaire PharmD, PhD 1 , Jacques Veslot 1 , Christian
Dina 1 , Christine Proença 1 , Stéphane Cauchi PhD 1 , Guillaume ... Related articles
- ►diabetesjournals.org M van Hoek, A Dehghan, J Witteman, CM van Duijn, … - Diabetes, 2008 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—We investigated 18 polymorphisms from recent GWA
studies on type 2 diabetes in the Rotterdam Study, a prospective, population-based study among
homogeneous Caucasian individuals of 55 years and older (genotyped subjects, n = ... Cited by 33 - Related articles - All 4 versions
H Lango, CNA Palmer, AD Morris, E Zeggini, AT … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVES—Genome-wide association studies have dramatically increased the number of
common genetic variants that are robustly associated with type 2 diabetes. A possible clinical
use of this information is to identify individuals at high risk of developing the disease, so ... Cited by 28 - Related articles - All 5 versions
S Cauchi, D Meyre, E Durand, C Proença, M Marre, S … - PloS one, 2008 - pubmedcentral.nih.gov In the same French population analyzed in our previous GWA study (3,295 T2D and 3,595
NGT), strong associations with T2D were found for CDKAL1 (OR rs7756992 =
1.30[1.19–1.42], P = 2.3×10 −9 ), CDKN2A/2B (OR rs10811661 = 0.74[0.66–0.82], P = ... Cited by 21 - Related articles - All 7 versions
MN Weedon, MI McCarthy, G Hitman, M Walker, … - PLoS …, 2006 - medicine.plosjournals.org Three common variants (Lys23 of KCNJ11, Pro12 of PPARG, and the T allele at rs7903146 of
TCF7L2) have been shown to predispose to type 2 diabetes mellitus across many large
studies. Risk allele frequencies ranged from 0.30 to 0.88 in controls. To assess the ... Cited by 98 - Related articles - Cached - All 15 versions
S Cauchi, KT Nead, H Choquet, F Horber, N … - BMC Medical …, 2008 - biomedcentral.com Amongst non-obese individuals, we observed significant T2D associations with HNF1A I27L
[odds ratio (OR) = 1.14, P = 0.04], GCK -30G>A (OR = 1.23, P = 0.01), SLC30A8 R325W (OR
= 0.87, P = 0.04), and TCF7L2 rs7903146 (OR = 1.89, P = 4.5 × 10 -23 ), and ... Cited by 15 - Related articles - Cached - All 9 versions
JB Meigs, P Shrader, LM Sullivan, JB … - The New England …, 2008 - nejm.highwire.org From the General Medicine Division (JB Meigs, PS), the Department of Medicine (JB Meigs,
PS, JCF), and the Center for Human Genetic Research and Diabe- tes Unit, Department of Medicine
(JB McAteer, JCF), Massachusetts General Hospital, Boston; the Department of Bio- ... Cited by 43 - Related articles - All 3 versions
- ►ahajournals.org W Marz, M Nauck, MM Hoffmann, D Nagel, BO Boehm, … - Circulation, 2004 - Am Heart Assoc From the Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University
of Graz, Graz, Austria (WM); Division of Clinical Chemistry, Department of Medicine, University
Hospital, Freiburg, Germany (MN, MMH); Institute of Clinical Chemistry, General Hospital, ... Cited by 27 - Related articles - All 8 versions
S Cauchi, D Meyre, H Choquet, C Dina, C Born, M … - Diabetes, 2006 - Am Diabetes Assoc Recently, case-control studies demonstrated that a TCF7L2 (transcription factor 7–like 2
gene) noncoding variant (rs7903146 T at-risk allele) was strongly associated with an increased
risk of type 2 diabetes. However, the predictive value of this marker in a nonselected ... Cited by 54 - Related articles - BL Direct - All 4 versions
