- ►pubget.com [PDF] H Li, Y Wu, RJF Loos, FB Hu, Y Liu, J Wang, Z … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— The minor allele frequencies of rs8050136, rs9939609, and rs9930506
in our population (0.12, 0.12, and 0.20, respectively) were substantially lower
than those observed for populations of European descent (eg, for CEU ... Cited by 48 - Related articles - BL Direct - All 5 versions
- ►u-tokyo.ac.jp [PDF] J Ohashi, I Naka, R Kimura, K Natsuhara, T … - Journal of Human Genetics, 2007 - Springer Abstract It has been suggested that Neel's ''thrifty genotype'' model may
account for high body weights in some Oceanic populations, which presumably
arose in modern times. In European populations, common variants ... Cited by 28 - Related articles - BL Direct - All 5 versions
- ►jlr.org K Wahlen, E Sjolin, J Hoffstedt - The Journal of Lipid Research, 2008 - ASBMB We investigated the rs9939609 single nucleotide polymorphism of the FTO gene in
relation to fat cell function and adipose tissue gene expression in 306 healthy
women with a wide range in body mass index (18–53 kg/m 2 ). Subcutaneous ... Cited by 28 - Related articles - All 7 versions
- ►diabetesjournals.org CH Andreasen, KL Stender-Petersen, MS … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—In studies of 3,856 type 2 diabetic case subjects and 4,861 normal
glucose-tolerant control subjects, the minor A-allele of rs9939609 associated
with type 2 diabetes (odds ratio 1.13 [95% CI 1.06–1.20], P = 9 × 10 ... Cited by 79 - Related articles - BL Direct - All 5 versions
- ►nih.gov K Hotta, Y Nakata, T Matsuo, S Kamohara, K … - Journal of human genetics, 2008 - Springer Abstract Variations in the fat-mass and obesity-associated gene (FTO) are
associated with the obesity phenotype in many Caucasian populations. This
association with the obesity phenotype is not clear in the Japanese. To ... Cited by 29 - Related articles - BL Direct - All 7 versions
SFA Grant, M Li, JP Bradfield, CE Kim, K … - PLos One, 2008 - pubmedcentral.nih.gov Recently an association was demonstrated between the single nucleotide
polymorphism (SNP), rs9939609, within the FTO locus and obesity as a consequence
of a genome wide association (GWA) study of type 2 diabetes in adults. We ... Cited by 20 - Related articles - All 6 versions
A Peeters, S Beckers, A Verrijken, P Roevens … - Molecular genetics and metabolism, 2008 - Elsevier A recent genome-wide search for susceptibility genes for type 2 diabetes
revealed a novel gene with an unknown function that contributes significantly to
common obesity when Frayling et al. (and the Wellcome Trust Case Control ... Cited by 35 - Related articles - All 3 versions
M Horikoshi, K Hara, C Ito, N Shojima, R … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Recently, several groups have carried out whole-genome
association studies in European and European- origin populations and found novel
type 2 diabetes- susceptibility genes, fat mass and obesity associated ... Cited by 50 - Related articles - BL Direct - All 2 versions
- ►nih.gov T Gerken, CA Girard, YCL Tung, CJ Webby, V … - Science, 2007 - sciencemag.org Variants in the FTO (fat mass and obesity associated) gene are associated with
increased body mass index in humans. Here, we show by bioinformatics analysis
that FTO shares sequence motifs with Fe(II)- and 2-oxoglutarate–dependent ... Cited by 140 - Related articles - BL Direct - All 8 versions
- ►endojournals.org R Fredriksson, M Hagglund, PK Olszewski, O … - Endocrinology, 2008 - Endocrine Soc Gene variants of the FTO (fatso) gene have recently been strongly associated
with body mass index and obesity. The FTO gene is well conserved and found in a
single copy in vertebrate species including fish and chicken, suggesting ... Cited by 39 - Related articles - BL Direct - All 4 versions
