C Gysemans, E van Etten, L Overbergh, A Giulietti, G … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— VDR −/− NOD mice are rachitic and have lower numbers of putative regulator cells
[TCR-α/β + CD4 − CD8 − (natural killer T-cells) and CD4 + CD25 + T-cells [in central and peripheral
immune organs compared with VDR +/+ NOD littermates. Lipopolysaccharide-stimulated ... Cited by 10 - Related articles - BL Direct - All 8 versions
- ►highwire.org E Baroni, M Biffi, F Benigni, A Monno, D … - Journal of leukocyte …, 2007 - jleuk.highwire.org 1,25-Dihydroxyvitamin D 3 [1,25(OH) 2 D 3 ] is a secosteroid hormone that regulates bone
metabolism, controls calcium homeostasis, and possesses immunomodulatory properties. We
show here that 1,25(OH) 2 D 3 contributes to the regulation of development and function ... Cited by 3 - Related articles - BL Direct - All 8 versions
DD Bikle - Clinical Reviews in Bone and Mineral Metabolism, 2009 - Springer Abstract Although the kidney was initially thought to be the sole organ responsible for the production
of 1,25(OH) 2 D 3 via its enzyme CYP27b1, it is now appreci- ated that the expression of CYP27b1
in tissues other than the kidney is wide spread. However, the kidney is the major source ... Cited by 2 - Related articles
- ►nih.gov A Wittke, A Chang, M Froicu, OF Harandi, V Weaver … - Archives of biochemistry …, 2007 - Elsevier Mice lacking the vitamin D receptor (VDR) are resistant to airway inflammation. Pathogenic immune
cells capable of transferring experimental airway inflammation to wildtype (WT) mice are present
and primed in the VDR KO mice. Furthermore, the VDR KO immune cells homed to the ... Cited by 10 - Related articles - All 4 versions
- ►fasebj.org J Ehrchen, L Helming, G Varga, B Pasche, K Loser, M … - The FASEB Journal, 2007 - FASEB We have previously reported that 1 ,25-dihydroxyvitamin D 3 (1 ,25(OH) 2 D 3 ) can selectively
suppress key functions of interferon-gamma (IFN- ) activated macrophages. To further explore
this mechanism for its relevance in vivo, we investigated an infection model that crucially ... Cited by 13 - Related articles - BL Direct - All 4 versions
JR Wu-Wong, M Nakane, J Ma, X Ruan, … - Journal of cellular …, 2007 - interscience.wiley.com Vitamin D analogs such as paricalcitol and calcitriol that activate the vitamin D receptor
(VDR) provide survival benefit for Stage 5 chronic kidney disease (CKD) patients, possibly associated
with a decrease in cardiovascular (CV)-related incidents. Phenotypic changes of smooth ... Cited by 5 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org S Hansdottir, MM Monick, SL Hinde, N Lovan … - The Journal of …, 2008 - Am Assoc Immnol The role of vitamin D in innate immunity is increasingly recognized. Recent work has identified
a number of tissues that express the enzyme 1 -hydroxylase and are able to activate vitamin
D. This locally produced vitamin D is believed to have important immunomodulatory ... Cited by 8 - Related articles - All 2 versions
R Rajapakse, M Mousli, AW Pfaff, B Uring-Lambert, … - Journal of Steroid …, 2005 - Elsevier The hormonal form of Vitamin D, 1,25-dihydroxyvitamin D3, is well known for its
immunosuppressive, anti-proliferative and pro-apoptotic activities. In the present work, we studied
the effect of 1,25-dihydroxyvitamin D3 on Toxoplasma gondii-infected mice. We observed ... Cited by 8 - Related articles - All 3 versions
- ►direct-ms.org [PDF] E van Etten, C Gysemans, DD Branisteanu, A … - Journal of Steroid …, 2007 - Elsevier The 1,25(OH) 2 D 3 analog, TX527 (19-nor-14,20-bisepi-23-yne-1,25(OH) 2 D 3 ), has an interesting
dissociation profile between its potent immunomodulatory and its calcemic effects in vivo. The
strong immunomodulatory potency of TX527 is reflected by its ability to attenuate ... Cited by 8 - Related articles - All 6 versions
[CITATION] The vitamin D receptor is necessary for 1, 25-dihydroxyvitamin D 3 to suppress …
