X Huang, RA Charbeneau, Y Fu, K Kaur, I … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Homozygous Gα i2 G184S knock-in mice show slightly reduced adiposity.
On a high-fat diet, male Gα i2 G184S mice are resistant to weight gain, have
decreased body fat, and are protected from insulin resistance. This appears ... Cited by 6 - Related articles - BL Direct - All 4 versions
R Roof, K Sobczyk-Kojiro, A Turbiak, D … - Chemical Biology and Drug Design, 2008 - interscience.wiley.com Regulators of G protein signaling accelerate GTP hydrolysis by Gα subunits and
profoundly inhibit signaling by G protein-coupled receptors. The distinct
expression patterns and pathophysiologic regulation of regulators of G ... Cited by 5 - Related articles - All 3 versions
Y Wang, Y Lee, J Zhang, KH Young - Pharmacology, 2008 - content.karger.com Regulators of G protein signaling (RGS) are a family of GTPase-activating
proteins (GAP) that interact with heterotrimeric G proteins in the negative
regulation of G-protein-coupled receptor (GPCR) signaling. RGS4, the first ... Cited by 4 - Related articles - All 4 versions
- ►nih.gov AJ Kimple, FS Willard, PM Giguère, CA … - BBA-Proteins and Proteomics, 2007 - Elsevier Regulator of G-protein signaling (RGS) proteins accelerate GTP hydrolysis by Gα
subunits and are thus crucial to the timing of G protein-coupled receptor (GPCR)
signaling. Small molecule inhibition of RGS proteins is an attractive ... Cited by 11 - Related articles - All 3 versions
RA Roof, Y Jin, DL Roman, RK Sunahara, M … - Chemical Biology and Drug Design, 2006 - interscience.wiley.com Regulators of G-protein signaling (RGS) accelerate guanine triphosphate
hydrolysis by Gα-subunits and profoundly inhibit signaling by G protein-coupled
receptors. The distinct expression patterns and pathophysiologic regulation ... Cited by 11 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org [PDF] X Huang, RA Charbeneau, Y Fu, K Kaur, I … - Diabetes, 2007 - Am Diabetes Assoc Page 1. Resistance to diet-induced obesity and improved insulin sensitivity
in mice with an RGS insensitive G184S Gnai2 allele Xinyan ... Cited by 1 - Related articles - All 2 versions
- ►cell.com M Jayaraman, H Zhou, L Jia, MD Cain, KJ … - Trends in Pharmacological Sciences, 2009 - Elsevier RGS (regulator of G protein signaling) proteins have emerged as crucial
regulators, effectors and integrators in G-protein-coupled receptor (GPCR)
signaling networks. Many RGS proteins accelerate GTP hydrolysis by Gα ... Cited by 4 - Related articles - All 3 versions
- ►physiology.org Y Fu, X Huang, L Piao, AN Lopatin, RR … - American Journal of Physiology- Heart and Circulatory …, 2007 - Am Physiological Soc G protein-coupled receptors play a pivotal role in regulating cardiac
automaticity. Their function is controlled by regulator of G protein signaling
(RGS) proteins acting as GTPase-activating proteins for G subunits to ... Cited by 6 - Related articles - BL Direct - All 5 versions
JJG Tesmer - Molecular Biology of RGS Proteins, 2009 - books.google.com Structure and Function of Regulator of G Protein Signaling Homology Domains John
JG Tesmer Department of Pharmacology, Life Sciences Institute, University of
Michigan, Ann Arbor, Michigan 48109‐2216 I. Introduction.................. ... Cited by 1 - Related articles
DL Roman - Molecular Biology of RGS Proteins, 2009 - books.google.com Identification of Ligands Targeting RGS Proteins: High‐Throughput Screening
and Therapeutic Potential David L. Roman Division of Medicinal and Natural
Products Chemistry, The University of Iowa College of Pharmacy, Iowa City, ... Related articles
