- ►diabetesjournals.org CH Andreasen, KL Stender-Petersen, MS … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—In studies of 3,856 type 2 diabetic case subjects and 4,861 normal
glucose-tolerant control subjects, the minor A-allele of rs9939609 associated
with type 2 diabetes (odds ratio 1.13 [95% CI 1.06–1.20], P = 9 × 10 ... Cited by 79 - Related articles - BL Direct - All 5 versions
A Peeters, S Beckers, A Verrijken, P Roevens … - Molecular genetics and metabolism, 2008 - Elsevier A recent genome-wide search for susceptibility genes for type 2 diabetes
revealed a novel gene with an unknown function that contributes significantly to
common obesity when Frayling et al. (and the Wellcome Trust Case Control ... Cited by 35 - Related articles - All 3 versions
- ►pubget.com [PDF] H Li, Y Wu, RJF Loos, FB Hu, Y Liu, J Wang, Z … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— The minor allele frequencies of rs8050136, rs9939609, and rs9930506
in our population (0.12, 0.12, and 0.20, respectively) were substantially lower
than those observed for populations of European descent (eg, for CEU ... Cited by 48 - Related articles - BL Direct - All 5 versions
C Dina, D Meyre, S Gallina, E Durand, A … - Nature genetics, 2007 - nature.com We identified a set of SNPs in the first intron of the FTO (fat mass and obesity
associated) gene on chromosome 16q12.2 that is consistently strongly associated
with early-onset and severe obesity in both adults and children of European ... Cited by 219 - Related articles - BL Direct - All 5 versions
- ►nih.gov T Gerken, CA Girard, YCL Tung, CJ Webby, V … - Science, 2007 - sciencemag.org Variants in the FTO (fat mass and obesity associated) gene are associated with
increased body mass index in humans. Here, we show by bioinformatics analysis
that FTO shares sequence motifs with Fe(II)- and 2-oxoglutarate–dependent ... Cited by 140 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org R Do, SD Bailey, K Desbiens, A Belisle, A … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—A genome-wide association study conducted by the Wellcome Trust Case
Control Consortium recently associated single nucleotide polymorphisms (SNPs) in
the FTO (fatso/fat mass and obesity associated) gene with type 2 diabetes. ... Cited by 29 - Related articles - BL Direct - All 3 versions
JO Clausen, PDA Sandbæk, DMST Lauritzen … - Am Diabetes Assoc MSc Camilla H. Andreasen1*, MSc Kirstine L. Stender-Petersen1*, BSc Mette S.
Mogensen1, MSc Signe S. Torekov1, MSc Lise Wegner1, PhD Gitte Andersen1, MSc
Arne L. Nielsen1, MSc Anders Albrechtsen2, DMSc Knut Borch-Johnsen1,3,4, MD ... Related articles
A Scuteri, S Sanna, WM Chen, M Uda, G Albai, … - PLoS Genet, 2007 - genetics.plosjournals.org The obesity epidemic is responsible for a substantial economic burden in
developed countries and is a major risk factor for type 2 diabetes and
cardiovascular disease. The disease is the result not only of several ... Cited by 223 - Related articles - Cached - All 11 versions
- ►jlr.org K Wahlen, E Sjolin, J Hoffstedt - The Journal of Lipid Research, 2008 - ASBMB We investigated the rs9939609 single nucleotide polymorphism of the FTO gene in
relation to fat cell function and adipose tissue gene expression in 306 healthy
women with a wide range in body mass index (18–53 kg/m 2 ). Subcutaneous ... Cited by 28 - Related articles - All 7 versions
- ►nih.gov K Hotta, Y Nakata, T Matsuo, S Kamohara, K … - Journal of human genetics, 2008 - Springer Abstract Variations in the fat-mass and obesity-associated gene (FTO) are
associated with the obesity phenotype in many Caucasian populations. This
association with the obesity phenotype is not clear in the Japanese. To ... Cited by 29 - Related articles - BL Direct - All 7 versions
