SM Reyna, S Ghosh, P Tantiwong, CS Meka, P Eagan, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— Obese and type 2 diabetic subjects had significantly elevated TLR4 gene expression
and protein content in muscle. TLR4 muscle protein content correlated with the severity of insulin
resistance. Obese and type 2 diabetic subjects also had lower IκBα content, an indication ... Cited by 14 - Related articles - All 5 versions
MS Radin, S Sinha, BA Bhatt, N Dedousis, RM O' … - Diabetologia, 2008 - Springer Page 1. ARTICLE Inhibition or deletion of the lipopolysaccharide receptor Toll-like
receptor-4 confers partial protection against lipid-induced insulin resistance in rodent skeletal
muscle MS Radin & S. Sinha & BA Bhatt & N. Dedousis & RM O'Doherty ... Cited by 8 - Related articles - BL Direct - All 2 versions
S Ghosh, A Choudary, S Ghosh, N Musi, Y Hu, … - Molecular …, 2009 - Endocrine Soc Aromatase (Cyp19) is a key enzyme in estrogen biosynthesis and an important target in breast
cancer therapy. Within tumor microenvironment, tumor cells stimulate aromatase expression
in adipose stromal cells (ASCs), which in turn promotes estrogen-dependent growth of ... Related articles - All 3 versions
A Monroy, S Kamath, AO Chavez, VE Centonze, M … - Diabetologia, 2009 - Springer Abstract Aims/hypothesis TNF-α levels are increased in obesity and type 2 diabetes. The regulation
of TNF-α converting enzyme (TACE) and its inhibitor, tissue inhibitor of metalloproteinase 3
(TIMP3), in human type 2 diabetes is unknown. Methods We examined TACE/TIMP3 ... Related articles - All 2 versions
- ►nrc-cnrc.gc.ca [PDF] M Francaux - Applied Physiology, Nutrition, and Metabolism, 2009 - article.pubs.nrc-cnrc.gc.ca Abstract: Toll-like receptors (TLRs) are transmembrane proteins that detect a variety of molecular
components mostly de- rived from microorganisms. TLR2 and TLR4 are amongst others present
in liver, adipose tissue, and skeletal muscle. Ex- tracellular long-chain fatty acids bind ... Related articles - View as HTML - All 5 versions
M Funaki - The Journal of Medical Investigation, 2009 - medical.med.tokushima-u.ac.jp Evolutionally, humans have developed the ability to store excess calorie intake in adipose tissue
as fat, which can be used in times of famine (1). Die- tary fat absorbed into epithelial cells of the
intestines is assembled into one type of lipoprotein, chylomi- crons, enters the ... Related articles - View as HTML - All 2 versions
EN Atochina-Vasserman, AJ Gow, H … - The Journal of …, 2009 - Am Assoc Immnol Pneumocystis pneumonia (PCP), the most common opportunistic pulmonary infection associated
with HIV infection, is marked by impaired gas exchange and significant hypoxemia. Immune
reconstitution disease (IRD) represents a syndrome of paradoxical respiratory failure in ... Cited by 1 - Related articles - All 2 versions
MW Foster, DT Hess, JS Stamler - Trends in Molecular Medicine, 2009 - Elsevier Protein S-nitrosylation constitutes a large part of the ubiquitous influence of nitric oxide on cellular
signal transduction and accumulating evidence indicates important roles for S-nitrosylation both
in normal physiology and in a broad spectrum of human diseases. Here we review recent ... Cited by 1 - Related articles - All 4 versions
A Khalaileh, T Gonen-Gross, J … - Diabetes, Obesity …, 2008 - interscience.wiley.com Recent studies have revealed a surprising plasticity of pancreatic β-cell mass. β-cell mass is
now recognized to increase and decrease in response to physiological demand, for example
during pregnancy and in insulin-resistant states. Moreover, we and others have shown ... Cited by 1 - Related articles - All 2 versions
