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Scholar Results 1 - 10 of about 101 related to Tomlinson: Impaired glucose tolerance and insulin resistance are associated with increased.... (0.10 sec) 

Impaired glucose tolerance and insulin resistance are associated with increased adipose …

- diabetesjournals.org [PDF] 
JW Tomlinson, J Finney, C Gay, BA Hughes, … - Diabetes, 2008 - Am Diabetes Assoc
Page 1. Glucocorticoid metabolism and insulin sensitivity 1 Impaired glucose
tolerance and insulin resistance are associated with ...
Cited by 3 - Related articles - All 5 versions

Increased A-ring reduction of glucocorticoids in obese Zucker rats: effects of insulin …


DE Livingstone, KJ McInnes, BR Walker, R … - Obesity research, 2005 - ncbi.nlm.nih.gov
OBJECTIVE: Obesity is associated with altered glucocorticoid metabolism, which
may impact on hypothalamic-pituitary-adrenal axis activity. Here we characterize
hepatic 5alpha- and 5beta-reductase in obese rats and their responses to ...
Cited by 8 - Related articles - BL Direct - All 2 versions

The role and regulation of 11β-hydroxysteroid dehydrogenase type 1 in the inflammatory …


KE Chapman, AE Coutinho, M Gray, JS Gilmour … - Molecular and Cellular Endocrinology, 2009 - Elsevier
Cortisone, a glucocorticoid hormone, was first used to treat rheumatoid
arthritis in humans in the late 1940s, for which Hench, Reichstein and Kendall
were awarded a Nobel Prize in 1950 and which led to the discovery of the ...
Cited by 3 - Related articles - All 3 versions

Depot-specific regulation of the conversion of cortisone to cortisol in human adipose tissue


MJ Lee, SK Fried, SS Mundt, Y Wang, S … - Obesity, 2008 - nature.com
Type 1 HSD (HSD1) mRNA and reductase activity were mainly expressed within
adipocytes and tightly correlated with adipocyte size within both depots. There
was no depot difference in HSD1 expression or reductase activity, while ...
Cited by 3 - Related articles - All 3 versions

[CITATION] Increased 5-reductase and normal 11-hydroxysteroid dehydrogenase metabolism of C19 and …


D Chin, C Shackleton, VK Prasad, B Kohn, R … - J Pediatr Endocrinol Metab, 2000
Cited by 3 - Related articles

Liver is the site of splanchnic cortisol production in obese nondiabetic humans


R Basu, A Basu, M Grudzien, P Jung, P … - Diabetes, 2009 - Am Diabetes Assoc
RESULTS—Ratios of arterial and portal vein D4 cortisol/cortisol total (0.06 ±
0.01 vs. 0.06 ± 0.01) and D4 cortisol/D3 cortisol (1.80 ± 0.14 vs. 1.84 ±
0.14) did not differ, indicating that no visceral cortisol production or ...
Cited by 3 - Related articles - All 3 versions

[CITATION] Sö derberg S, Andrew R, Livingstone DE, Johnson O, Walker BR 2001 Tissue-specific …


E Rask, T Olsson - J Clin Endocrinol Metab
Cited by 2 - Related articles

11beta-hydroxysteroid dehydrogenase type 1 regulation by intracellular glucose 6- …

- jbc.org
EA Walker, A Ahmed, GG Lavery, JW … - Journal of Biological Chemistry, 2007 - ASBMB
Microsomal glucose-6-phosphatase- (G6Pase- ) and glucose 6-phosphate transporter
(G6PT) work together to increase blood glucose concentrations by performing the
terminal step in both glycogenolysis and gluconeogenesis. Deficiency of the ...
Cited by 14 - Related articles - All 5 versions

Dietary macronutrient content alters cortisol metabolism independently of body weight …

- endojournals.org
RH Stimson, AM Johnstone, NZM Homer, DJ … - Journal of Clinical Endocrinology & Metabolism, 2007 - Endocrine Soc
Context: Dietary macronutrient composition influences cardiometabolic health
independently of obesity. Both dietary fat and insulin alter glucocorticoid
metabolism in rodents and, acutely, in humans. However, whether longer-term ...
Cited by 9 - Related articles - BL Direct - All 5 versions

Reduced glucocorticoid production rate, decreased 5α-reductase activity, and adipose tissue …


JW Tomlinson, J Finney, BA Hughes, SV … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—Before weight loss, fat mass correlated with glucocorticoid secretion
rate (total fat, r = 0.46, P < 0.05; trunk fat, r = 0.52, P < 0.05); however,
glucocorticoid secretion rate was inversely related to insulin sensitivity ...
Cited by 9 - Related articles - All 4 versions


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