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Scholar Results 1 - 10 of about 101 related to Chakravarthy: Decreased fetal size is associated with β-cell hyperfunction in early life.... (0.11 sec) 

Decreased fetal size is associated with β-cell hyperfunction in early life and failure with age

- nih.gov
MV Chakravarthy, Y Zhu, MB Wice, T … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—FASDEL mice did not manifest catch-up growth or insulin resistance.
β-Cell mass and insulin secretion were strikingly increased in young FASDEL
mice, but β-cell failure and diabetes occurred with age. FASDEL β-cells ...
Cited by 2 - Related articles - All 4 versions

[CITATION] β-Cell dysfunction in type 2 diabetes mellitus


JL Leahy - Joslin's Diabetes Mellitus. 14th ed. Kahn CR, Weir GC, …, 2005
Cited by 3 - Related articles

IGF-1 Mediates PTEN Suppression and Enhances Cell Invasion and Proliferation via …


J Ma, H Sawai, Y Matsuo, N Ochi, A Yasuda, … - Journal of Surgical Research, 2008 - Elsevier
Type-1 insulin-like growth factor (IGF-1) up-regulates cell proliferation and
invasiveness through activation of PI3K/Akt signaling pathway. IGF-1 also
down-regulates the tumor suppressor chromosome 10 (PTEN). We investigated ...
Cited by 3 - Related articles - All 2 versions

[CITATION] Multihormonal regulation of insulin-like growth factor binding protein-1 in rat H411E hepatoma …


TG Unterman, DT Oehler, LJ Murphy, RG … - Endocrinology, 1991
Cited by 4 - Related articles

Glucagon and GLP-1 stimulate IGFBP-1 secretion in Hep G2 cells without effect on IGFBP- …


A Hilding, C Möller, KE Hall - Growth Hormone & IGF Research, 2002 - Elsevier
Glucagon has previously been reported to increase serum levels of insulin-like
growth factor binding protein-1 (IGFBP-1) in humans. The in vitro effect of
glucagon and glucagon-like peptide-1 (7–36) amide (GLP-1) was ...
Cited by 5 - Related articles - BL Direct - All 3 versions

Specific cleavage of insulin-like growth factor-binding protein-1 by a novel protease activity


J Wang, J Shafqat, K Hall, M Ståhlberg, IL … - Cellular and molecular life sciences, 2006 - Springer
Abstract. Insulin-like growth factor-binding protein-1 (IGFBP-1) is secreted in
a highly phosphorylated form that binds IGF-I with high affinity and is
resistant to proteoly- sis. We have purified IGFBP-1-specific protease ...
Cited by 5 - Related articles - BL Direct - All 6 versions

PTEN expression contributes to the regulation of muscle protein degradation in diabetes

- diabetesjournals.org
Z Hu, IH Lee, X Wang, H Sheng, L Zhang, J … - Diabetes, 2007 - Am Diabetes Assoc
RESULTS—In acutely diabetic mice, muscle PTEN expression was decreased. It was
increased by chronic diabetes or insulin resistance. In cultured C2C12 myotubes,
acute suppression of PI3K activity led to decreased PTEN expression, while ...
Cited by 7 - Related articles - BL Direct - All 4 versions

Focal adhesion kinase regulates insulin resistance in skeletal muscle


B Bisht, HL Goel, CS Dey - Diabetologia, 2007 - Springer
Abstract Aims/hypothesis On the basis of our previous studies, we investigated
the possible role of focal adhesion kinase (FAK) in the development of insulin
resistance in skeletal muscle, a major organ responsible for ...
Cited by 7 - Related articles - BL Direct - All 5 versions

Insulin-like growth factor-binding protein-1 in the prediction and development of type 2 …


MS Lewitt, A Hilding, CG Östenson, S Efendic, … - Diabetologia, 2008 - Springer
Abstract Aims/hypothesis Insulin-like growth factor-binding protein- 1 (IGFBP-1)
production in the liver is inhibited by insulin, and low circulating levels are
associated with the metabolic syndrome. The aim of this study was to ...
Cited by 8 - Related articles - BL Direct - All 2 versions

Insulin-like growth factor binding protein-2(IGFBP-2) is a marker for the metabolic syndrome


AH Heald, K Kaushal, KW Siddals, AS … - Experimental and clinical endocrinology & diabetes, 2006 - cat.inist.fr
Aims/hypothesis: IGFs and their binding proteins are increasingly recognised as
important in understanding the pathogenesis of cardiovascular disease. Low
IGFBP-1, particularly coupled with low IGF-I, is associated with increased ...
Cited by 8 - Related articles - BL Direct - All 3 versions


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