- ►nih.gov MV Chakravarthy, Y Zhu, MB Wice, T … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—FASDEL mice did not manifest catch-up growth or insulin resistance.
β-Cell mass and insulin secretion were strikingly increased in young FASDEL
mice, but β-cell failure and diabetes occurred with age. FASDEL β-cells ... Cited by 2 - Related articles - All 4 versions
[CITATION] β-Cell dysfunction in type 2 diabetes mellitus
J Ma, H Sawai, Y Matsuo, N Ochi, A Yasuda, … - Journal of Surgical Research, 2008 - Elsevier Type-1 insulin-like growth factor (IGF-1) up-regulates cell proliferation and
invasiveness through activation of PI3K/Akt signaling pathway. IGF-1 also
down-regulates the tumor suppressor chromosome 10 (PTEN). We investigated ... Cited by 3 - Related articles - All 2 versions
[CITATION] Multihormonal regulation of insulin-like growth factor binding protein-1 in rat H411E hepatoma …
A Hilding, C Möller, KE Hall - Growth Hormone & IGF Research, 2002 - Elsevier Glucagon has previously been reported to increase serum levels of insulin-like
growth factor binding protein-1 (IGFBP-1) in humans. The in vitro effect of
glucagon and glucagon-like peptide-1 (7–36) amide (GLP-1) was ... Cited by 5 - Related articles - BL Direct - All 3 versions
J Wang, J Shafqat, K Hall, M Ståhlberg, IL … - Cellular and molecular life sciences, 2006 - Springer Abstract. Insulin-like growth factor-binding protein-1 (IGFBP-1) is secreted in
a highly phosphorylated form that binds IGF-I with high affinity and is
resistant to proteoly- sis. We have purified IGFBP-1-specific protease ... Cited by 5 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org Z Hu, IH Lee, X Wang, H Sheng, L Zhang, J … - Diabetes, 2007 - Am Diabetes Assoc RESULTS—In acutely diabetic mice, muscle PTEN expression was decreased. It was
increased by chronic diabetes or insulin resistance. In cultured C2C12 myotubes,
acute suppression of PI3K activity led to decreased PTEN expression, while ... Cited by 7 - Related articles - BL Direct - All 4 versions
B Bisht, HL Goel, CS Dey - Diabetologia, 2007 - Springer Abstract Aims/hypothesis On the basis of our previous studies, we investigated
the possible role of focal adhesion kinase (FAK) in the development of insulin
resistance in skeletal muscle, a major organ responsible for ... Cited by 7 - Related articles - BL Direct - All 5 versions
MS Lewitt, A Hilding, CG Östenson, S Efendic, … - Diabetologia, 2008 - Springer Abstract Aims/hypothesis Insulin-like growth factor-binding protein- 1 (IGFBP-1)
production in the liver is inhibited by insulin, and low circulating levels are
associated with the metabolic syndrome. The aim of this study was to ... Cited by 8 - Related articles - BL Direct - All 2 versions
AH Heald, K Kaushal, KW Siddals, AS … - Experimental and clinical endocrinology & diabetes, 2006 - cat.inist.fr Aims/hypothesis: IGFs and their binding proteins are increasingly recognised as
important in understanding the pathogenesis of cardiovascular disease. Low
IGFBP-1, particularly coupled with low IGF-I, is associated with increased ... Cited by 8 - Related articles - BL Direct - All 3 versions