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Scholar Results 1 - 10 of about 101 related to El Ouaamari: miR-375 targets 3′-phosphoinositide–dependent protein kinase-1 and regulates.... (0.13 sec) 

miR-375 targets 3′-phosphoinositide–dependent protein kinase-1 and regulates glucose- …

- nih.gov
A El Ouaamari, N Baroukh, GA Martens, P … - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—MicroRNAs are short, noncoding RNAs that regulate gene expression.
We hypothesized that the phosphatidylinositol 3-kinase (PI 3-kinase) cascade
known to be important in β-cell physiology could be regulated by ...
Cited by 10 - Related articles - All 5 versions

MicroRNAs induced during adipogenesis that accelerate fat cell development are …


H Xie, B Lim, HF Lodish - Diabetes, 2009 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS Using miRNA microarrays, we profiled the expression
of >370 miRNAs during adipogenesis of preadipocyte 3T3-L1 cells and adipocytes
from leptin deficient ob/ob and diet-induced obese mice. Changes in key ...
Cited by 7 - Related articles - All 3 versions

Identification of glucose-regulated miRNAs from pancreatic β cells reveals a role for miR-30d …

- cshlp.org
X Tang, L Muniappan, G Tang, S Özcan - Rna, 2009 - rnajournal.cshlp.org
MicroRNAs (miRNAs) are small noncoding ribonucleotides that bind mRNAs and
function mainly as translational repressors in mammals. MicroRNAs have been
implicated to play a role in many diseases, including diabetes. Several ...
Cited by 8 - Related articles - All 4 versions

Alterations in MicroRNA Expression Contribute to Fatty Acid–Induced Pancreatic β-Cell …

- nih.gov
P Lovis, E Roggli, DR Laybutt, S Gattesco, … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—Prolonged exposure of the β-cell line MIN6B1 and pancreatic islets to
palmitate causes a time- and dose-dependent increase of miR34a and miR146.
Elevated levels of these miRNAs are also observed in islets of diabetic ...
Cited by 8 - Related articles - All 4 versions

miR-375 targets PDK1 and regulates glucose-induced biological responses in pancreatic β- …

- diabetesjournals.org [PDF] 
A El Ouaamari, N Baroukh, GA Martens, P … - Diabetes, 2008 - Am Diabetes Assoc
INSERM, U907, Nice, F-06107, France; Université de Nice-Sophia Antipolis,
Faculté de Médecine, Institut de Génétique et Signalisation Moléculaire
(IFR50), Nice, F-06107, France. ... Diabetes Research Center, Brussels ...
Cited by 5 - Related articles - All 2 versions

Quantitative differential expression analysis reveals miR-7 as major islet microRNA

- diabetesresearch.org [PDF] 
V Bravo-Egana, S Rosero, RD Molano, A … - Biochemical and Biophysical Research …, 2008 - Elsevier
MicroRNAs (miRNAs) are non-coding gene products that regulate gene expression
through specific binding to target mRNAs. Cell-specific patterns of miRNAs are
associated with the acquisition and maintenance of a given phenotype, such ...
Cited by 11 - Related articles - All 4 versions

MicroRNA-320 expression in myocardial microvascular endothelial cells and its relationship …


XH Wang, RZ Qian, W Zhang, SF Chen, HM … - Clin Exp Pharmacol Physiol, 2009 - pt.wkhealth.com
Cited by 7 - Related articles - All 6 versions

Role of microRNAs in diabetes

- uky.edu [PDF] 
X Tang, G Tang, S Özcan - BBA-Gene Regulatory Mechanisms, 2008 - Elsevier
Diabetes is one of the most common chronic diseases in the world. Multiple and
complex factors including various genetic and physiological changes can lead to
type 1 and type 2 diabetes. However, the major mechanisms underlying the ...
Cited by 14 - Related articles - All 4 versions

[PDF] A truth serum for cancer—microRNAs have major potential as cancer biomarkers


LJ Chin, FJ Slack - Cell Research, 2008 - gene-quantification.de
1 Department of Molecular, Cellular and Developmental Biology, Yale University,
PO Box 208103, New Haven, CT 06520, USA Correspondence: Frank J Slack,
E-mail:frank.slack@yale.edu Cell Research (2008) 18:983-984. doi: ...
Cited by 8 - Related articles - View as HTML - All 4 versions

Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice


E Zhao, MP Keller, ME Rabaglia, AT Oler, DS … - Mammalian Genome, 2009 - Springer
Abstract Type 2 diabetes results from severe insulin resistance coupled with a
failure of b cells to compensate by secreting sufficient insulin. Multiple
genetic loci are involved in the development of diabetes, although the ...
Cited by 1 - Related articles - All 2 versions


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