P Lovis, E Roggli, DR Laybutt, S Gattesco, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Prolonged exposure of the β-cell line MIN6B1 and pancreatic islets to
palmitate causes a time- and dose-dependent increase of miR34a and miR146.
Elevated levels of these miRNAs are also observed in islets of diabetic ... Cited by 8 - Related articles - All 4 versions
H Xie, B Lim, HF Lodish - Diabetes, 2009 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS Using miRNA microarrays, we profiled the expression
of >370 miRNAs during adipogenesis of preadipocyte 3T3-L1 cells and adipocytes
from leptin deficient ob/ob and diet-induced obese mice. Changes in key ... Cited by 7 - Related articles - All 3 versions
- ►cshlp.org X Tang, L Muniappan, G Tang, S Özcan - Rna, 2009 - rnajournal.cshlp.org MicroRNAs (miRNAs) are small noncoding ribonucleotides that bind mRNAs and
function mainly as translational repressors in mammals. MicroRNAs have been
implicated to play a role in many diseases, including diabetes. Several ... Cited by 8 - Related articles - All 4 versions
A El Ouaamari, N Baroukh, GA Martens, P … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—MicroRNAs are short, noncoding RNAs that regulate gene expression.
We hypothesized that the phosphatidylinositol 3-kinase (PI 3-kinase) cascade
known to be important in β-cell physiology could be regulated by ... Cited by 11 - Related articles - All 5 versions
- ►pnas.org MN Poy, J Hausser, M Trajkovski, M Braun, S … - Proceedings of the National Academy of Sciences, 2009 - National Acad Sciences Altered growth and development of the endocrine pancreas is a frequent cause of
the hyperglycemia associated with diabetes. Here we show that microRNA-375
(miR-375), which is highly expressed in pancreatic islets, is required for ... Cited by 10 - Related articles - All 12 versions
[CITATION] Regulation of the expression of components of the machinery of exocytosis of insulin- …
T Sun, M Fu, AL Bookout, SA Kliewer, DJ … - Molecular Endocrinology, 2009 - Endocrine Soc Differentiation of 3T3-L1 cells into adipocytes involves a highly orchestrated
series of events including clonal expansion, growth arrest, and terminal
differentiation. The mechanisms coordinating these different steps are not ... Cited by 7 - Related articles - All 3 versions
- ►uky.edu [PDF] X Tang, G Tang, S Özcan - BBA-Gene Regulatory Mechanisms, 2008 - Elsevier Diabetes is one of the most common chronic diseases in the world. Multiple and
complex factors including various genetic and physiological changes can lead to
type 1 and type 2 diabetes. However, the major mechanisms underlying the ... Cited by 14 - Related articles - All 4 versions
H Xie, L Sun, HF Lodish, 2009 - Informa Pharma Science Obesity is a serious health problem worldwide associated with an increased risk
of life-threatening diseases such as type 2 diabetes, atherosclerosis, and
certain types of cancer. Fundamental for the development of novel ... Related articles - All 5 versions
