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Scholar Results 1 - 10 of about 101 related to Ku: Inducible overexpression of sFlt-1 in podocytes ameliorates glomerulopathy in diabetic mice. (0.13 sec) 

Inducible overexpression of sFlt-1 in podocytes ameliorates glomerulopathy in …

- diabetesjournals.org
CH Ku, KE White, A Dei Cas, A Hayward, Z Webster, R … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—Nondiabetic DOX-treated transgenic mice showed a twofold increase in cortex
sFlt-1 expression and a fourfold increase in sFlt-1 urine excretion (P < 0.001). Urine free
VEGF-A was decreased by 50%, and cortex VEGF-A expression was upregulated by 30% ...
Cited by 3 - Related articles - All 6 versions

Beneficial effects of the Rho kinase inhibitor Y27632 in murine puromycin …


L Wang, MJ Ellis, TA Fields, DN Howell, RF … - Kidney Blood Press …, 2008 - content.karger.com
Fax +41 61 306 12 34 E-Mail karger@karger.ch www.karger.com ... Kidney Blood Press Res
2008;31:111–121 DOI: 10.1159/000121531 ... Liming Wang a Mathew J. Ellis a Timothy A. Fields
b David N. Howell b ... Y27632. Conclusions:The ROCK inhibitor Y27632 attenuated ...
Cited by 2 - Related articles - BL Direct - All 4 versions

Amelioration of crescentic glomerulonephritis by RhoA kinase inhibitor, Fasudil, …

- amjpathol.org
T Hidaka, Y Suzuki, M Yamashita, T Shibata, Y … - American Journal of …, 2008 - ASIP
The small GTPase RhoA is activated by the angiotensin II (AngII) type 1 receptor (AT1R), which
is part of the local renin-angiotensin system that is involved in podocyte injury preceding glomerular
crescent formation. We demonstrated previously that inhibition of AT1R protects against ...
Cited by 2 - Related articles - BL Direct - All 4 versions

Angiostatin overexpression is associated with an improvement in chronic kidney …


W Mu, DA Long, X Ouyang, A Agarwal, PE … - American Journal of …, 2009 - Am Physiological Soc
51 articles, 28 of which you can access free at: This article cites http://ajprenal.physiology.org
/cgi/content/full/296/1/F145#BIBL ... 2 other HighWire hosted articles: This article has been cited
by ... [PDF] [Full Text] , May 1, 2009; 24 (5): 1384-1387. Nephrol. Dial. Transplant. P. ...
Cited by 3 - Related articles - All 3 versions

Dissociation of NEPH1 from nephrin is involved in development of a rat model of …

- physiology.org [PDF] 
Y Otaki, N Miyauchi, M Higa, A Takada, T … - American Journal of …, 2008 - Am Physiological Soc
American Physiological Society. ISSN: 0363-6127, ESSN: 1522-1466. Visit our website at
(monthly) by the American Physiological Society, 9650 Rockville Pike, Bethesda MD
20814-3991. Copyright © 2005 by the respective cells and vasculature, as well as to the ...
Cited by 3 - Related articles - All 3 versions

Vascular endothelial growth factor-C, a potential paracrine regulator of glomerular …

- amjpathol.org
RR Foster, SC Slater, J Seckley, D Kerjaschki, DO … - American Journal of …, 2008 - ASIP
We have previously reported expression of vascular endothelial growth factor (VEGF)-A and
-C in glomerular podocytes and actions of VEGF-A on glomerular endothelial cells (GEnC) that
express VEGF receptor-2 (VEGFR-2). Here we define VEGFR-3 expression in GEnC and ...
Cited by 3 - Related articles - All 5 versions

Lowering blood pressure blocks mesangiolysis and mesangial nodules, but not …

- amjpathol.org
T Kosugi, M Heinig, T Nakayama, T Connor, Y … - American Journal of …, 2009 - ASIP
Recently, we and others reported that diabetic endothelial nitric oxide synthase knockout
(eNOSKO) mice develop advanced glomerular lesions that include mesangiolysis and nodular
lesions. Interestingly, insulin treatment lowered blood pressure and prevented renal ...
Cited by 3 - Related articles - All 5 versions

Rosuvastatin protects against podocyte apoptosis in vitro

- oxfordjournals.org
FC Cormack-Aboud, PT Brinkkoetter, JW Pippin, … - Nephrology Dialysis …, 2008 - ERA-EDTA
Background. Clinical studies suggest that statins reduce proteinuria and slow the decline in kidney
function in chronic kidney disease. Given a rich literature identifying podocyte apoptosis as an
early step in the pathophysiological progression to proteinuria and glomerulosclerosis, ...
Cited by 3 - Related articles - All 4 versions

Activation of adenosine 2A receptors preserves structure and function of podocytes

- asnjournals.org
AS Awad, M Rouse, L Liu, AL Vergis, DL … - Journal of the American …, 2008 - Am Soc Nephrol
Adenosine 2A receptor (A 2A R) activation was recently shown to be renoprotective in diabetic
nephropathy. A 2A R are found in glomeruli and have been shown to associate with the podocyte
cytoskeletal protein -actinin-4, but the effect of their activation on podocyte structure and ...
Cited by 4 - Related articles - All 8 versions

Establishment of conditionally immortalized mouse glomerular parietal epithelial …

- asnjournals.org
T Ohse, JW Pippin, MR Vaughan, PT … - Journal of the American …, 2008 - Am Soc Nephrol
Parietal epithelial cells (PEC) are major constituents of crescents in crescentic
glomerulonephritis. The purpose of these studies was to establish an immortalized PEC cell
line with similar characteristics to PEC in vivo for use in future mechanistic studies. ...
Cited by 4 - Related articles - All 6 versions


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