- ►diabetesjournals.org IR Lanza, DK Short, KR Short, S … - Diabetes, 2008 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS— Insulin sensitivity was measured by
hyperinsulinemic-euglycemic clamp and ATP production in mitochondria isolated
from vastus lateralis biopsies of 42 healthy sedentary and ... Cited by 15 - Related articles - All 4 versions
L Jin, H Galonek, K Israelian, W Choy, M … - Protein Sci, 2009 - interscience.wiley.com SIRT3 is a key mitochondrial protein deacetylase proposed to play key roles in
regulating mitochondrial metabolism but there has been considerable debate about
its actual size, the sequences required for activity, and its subcellular ... Cited by 4 - Related articles - All 3 versions
IK Law, L Liu, A Xu, KS Lam, PM Vanhoutte, … - Proteomics, 2009 - interscience.wiley.com Sirtuins are a family of NAD + -dependent protein deacetylases that regulate
cellular functions through deacetylation of a wide range of protein targets.
Overexpression of Sir2, the first gene discovered in this family, is able ... Cited by 4 - Related articles - All 2 versions
H Cooper, J Spelbrink - Biochem. J, 2008 - biochemj.org It has recently been suggested that perhaps as many as 20% of all mitochondrial
proteins are regulated through lysine acetylation while SIRT3 has been
implicated as an important mitochondrial protein deacetylase. It is ... Cited by 19 - Related articles - Cached - BL Direct - All 5 versions
C Schlicker, M Gertz, P Papatheodorou, B … - Journal of Molecular Biology, 2008 - Elsevier The enzymes of the Sirtuin family of nicotinamide-adenine-dinucleotide-dependent
protein deacetylases are emerging key players in nuclear and cytosolic
signaling, but also in mitochondrial regulation and aging. Mammalian ... Cited by 20 - Related articles - All 3 versions
- ►pnas.org BH Ahn, HS Kim, S Song, IH Lee, J Liu, A … - Proceedings of the National Academy of Sciences, 2008 - National Acad Sciences Here, we demonstrate a role for the mitochondrial NAD-dependent deacetylase
Sirt3 in the maintenance of basal ATP levels and as a regulator of mitochondrial
electron transport. We note that Sirt3 −/− mouse embryonic fibroblasts ... Cited by 22 - Related articles - All 6 versions
T Nakagawa, DJ Lomb, MC Haigis, L … - Cell, 2009 - Elsevier Sirtuins are NAD-dependent protein deacetylases that connect metabolism and
aging. In mammals, there are seven sirtuins (SIRT1-7), three of which are
associated with mitochondria. Here, we show that SIRT5 localizes in the ... Cited by 11 - Related articles - All 5 versions
- ►cnfindpark.cn IR Lanza, KS Nair - American Journal of Clinical Nutrition, 2009 - Am Soc Nutrition Aging has been reported to be accompanied by reduced mitochondrial function and
insulin sensitivity. Whether these deleterious effects result from chronological
age or lifestyle-related factors such as adiposity and physical inactivity ... Cited by 9 - Related articles - All 6 versions
IR Lanza, KS Nair - Mitochondrial Function, Part B: Mitochondrial Protein …, 2009 - books.google.com > CHAPTER TWENTY Functional Assessment of Isolated Mitochondria In Vitro Ian R.
Lanza and K. Sreekumaran Nair Contents 1. Introduction 350 2. Mitochondrial
Isolation Procedures 354 2.1. Tissue homogenization 355 2.2. Separation of ... Cited by 1 - Related articles - All 2 versions
AM Distler, J Kerner, K Lee, CL Hoppel - Methods in Enzymology, 2009 - Elsevier In recent years, a wide variety of proteomic approaches using gel
electrophoresis and mass spectrometry has been developed to detect
post-translational modifications. Mitochondria are often a focus of these ... Cited by 2 - Related articles - All 4 versions
