BO Boehm, P Möller, J Högel, BR Winkelmann, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Significantly enhanced telomere attrition was seen in all LURIC
subjects compared with healthy control subjects. Although the average
telomere-length loss is equivalent to well >10 years of healthy aging, ... Related articles - All 3 versions
WR Engels, DM Johnson-Schlitz, C Flores, … - Cell cycle, 2007 - cat.inist.fr Until recently, the connection between aging and DNA repair has rested on two
classes of observation. First, DNA damage and unrepaired double-strand
breaks(DSBs) accumulate with age. Second, several defects in DNA repair ... Cited by 11 - Related articles - BL Direct - All 4 versions
A Wojda, M Witt - Journal of applied genetics, 2003 - jag.igr.poznan.pl Abstract. The effects of ageing in humans appear to be a combination of
influence of genetically programmed phenomena and exogenous environmental
factors, and take place at the cellular level (senescence), rather than at ... Cited by 14 - Related articles - View as HTML - BL Direct - All 6 versions
- ►physiology.org [PDF] MT Barati, ML Merchant, AB Kain, AW Jevans, … - American Journal of Physiology- Renal Physiology, 2007 - Am Physiological Soc Page 1. Proteomic Analysis Defines Altered Cellular Redox Pathways and Advanced
Glycation End Product (AGE) Metabolism in Glomeruli of db/db Diabetic Mice ... Cited by 15 - Related articles - BL Direct - All 4 versions
L Migliore, R Barale, E Bosco, F Giorgelli, M … - Carcinogenesis, 1990 - Oxford Univ Press The mutagenic activity of methylglyoxal (MG) was assayed in vitro in human
lymphocytes [induction of chromosomal aberrations (CAs), sister chromatid
exchanges (SCEs) and micronuclei] both in the presence and in the absence ... Cited by 17 - Related articles - All 3 versions
- ►cell.com AN Vallejo - Trends in molecular medicine, 2007 - Elsevier Immunological studies of aging and of patients with chronic immune-mediated
diseases document overlap of immune phenotypes. Here, the term 'immune
remodeling' refers to these phenotypes that are indicative of biological ... Cited by 19 - Related articles - All 6 versions
RA Kleinerman, LG Littlefield, RE Tarone, AM … - Radiation research, 1990 - jstor.org Structural chromosome aberrations were evaluated in periph- eral blood samples
obtained from three populations exposed to partial-body irradiation. These
included 143 persons who re- ceived radiotherapy for enlarged thymus glands ... Cited by 21 - Related articles - All 5 versions
A Bürkle - Free radical research, 2006 - informahealthcare.com Half a century ago, when the free radical theory of aging was first proposed,
the damaging effects of reactive oxygen species (ROS) were in the focus of
attention and considered the single most important determinant of aging. ... Cited by 19 - Related articles - All 5 versions
Z Lou, J Chen - Experimental cell research, 2006 - Elsevier Aging is a complex process that results in functional decline and mortality of
the organisms. On the cellular lever, cellular senescence has been used as a
model for aging. Therefore, understanding cellular senescence has important ... Cited by 23 - Related articles - All 5 versions
EJ Tawn, CL Cartmell - Mutation research, 1989 - ncbi.nlm.nih.gov Cytogenetic analysis was performed on blood lymphocyte cultures from 12 moderate
smokers (15-20 cigarettes/day) and 12 non-smokers. An increase in dicentrics was
observed in the smokers using block-stained material but this was not ... Cited by 22 - Related articles - All 2 versions
