- ►diabetesjournals.org T Senokuchi, CP Liang, TA Seimon, S Han, M … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Insulin-resistant macrophages showed attenuated Akt activation and increased
nuclear localization of FoxO1 during endoplasmic reticulum stress induced by free cholesterol
loading. Overexpression of active FoxO1 or FoxO3 failed to induce apoptosis in ... Cited by 7 - Related articles - All 4 versions
- ►diabetesjournals.org [PDF] T Senokuchi, CP Liang, TA Seimon, S Han, M … - Diabetes, 2008 - Am Diabetes Assoc Takafumi Senokuchi, MD, PhD*1, Chien-Ping Liang, PhD1, Tracie A. Seimon, PhD1, Seongah
Han, PhD1, Michihiro Matsumoto, MD, PhD1, Alexander S. Banks1, Ji-Hye Paik, PhD3, Ronald
A. DePinho, MD, PhD3, Domenico Accili, MD, PhD1, Ira Tabas, MD, PhD1,2, and Alan R. ... Cited by 4 - Related articles - All 2 versions
A Ryan, M Murphy, C Godson, FB Hickey - Apoptosis - Springer Abstract Since the early observation that similarities between thyroiditis and insulitis existed,
the important role played by inflammation in the development of diabetes has been
appreciated. More recently, experiments have shown that inflammation also plays a ... Related articles - All 2 versions
M Nomura, H Ishii, A Kawakami, M … - American Journal of …, 2009 - Am Physiological Soc The present study attempted to define the role of hepatic Niemann-Pick C1-like 1 (NPC1L1),
a cholesterol transporter, in hepatic insulin resistance as well as hepatic steatosis. The inhibition
of NPC1L1 and its molecular consequences were examined in Zucker obese fatty (ZOF) ... Cited by 1 - Related articles - All 3 versions
S Li, Y Sun, CP Liang, EB Thorp, S Han, AW … - Circulation …, 2009 - Am Heart Assoc Kluwer Health, 351 West Camden Street, Baltimore, MD 21202-2436. Phone:
410-528-4050. Permissions: Permissions & Rights Desk, Lippincott Williams & Wilkins, a division
of Wolters ... Defective Phagocytosis of Apoptotic Cells by Macrophages Related articles - All 2 versions
C Fernandez-Hernando, L Jozsef, D Jenkins, … - … , and Vascular Biology, 2009 - Am Heart Assoc Kluwer Health, 351 West Camden Street, Baltimore, MD 21202-2436. Phone:
410-528-4050. Permissions: Permissions & Rights Desk, Lippincott Williams & Wilkins, a division
of Wolters ... Absence of Akt1 Reduces Vascular Smooth Muscle Cell Related articles - All 2 versions
YY Shang, M Zhong, LP Zhang, ZX Guo, … - Clinical and …, 2009 - interscience.wiley.com C/EBP homologous protein (CHOP), an endoplasmic reticulum (ER) stress-inducible
protein, plays a critical role in the regulation of the cell cycle and apoptosis by forming heterodimers
with other C/EBP proteins; however, the regulation of its function remains to be ... Related articles - All 2 versions
T Seimon, I Tabas - The Journal of Lipid Research, 2009 - ASBMB Macrophage apoptosis is an important feature of atherosclerotic plaque development. Research
directed at understanding the functional consequences of macrophage death in atherosclerosis
has revealed opposing roles for apoptosis in atherosclerotic plaque progression. In early ... Cited by 16 - Related articles - All 4 versions
- ►cell.com C Fernández-Hernando, E Ackah, J Yu, Y Suárez, T … - Cell metabolism, 2007 - Elsevier The Akt signaling pathway controls several cellular functions in the cardiovascular system;
however, its role in atherogenesis is unknown. Here, we show that the genetic ablation of Akt1
on an apolipoprotein E knockout background (ApoE −/− Akt1 −/− ) increases aortic lesion ... Cited by 27 - Related articles - All 5 versions
- ►ahajournals.org WS Lim, JM Timmins, TA Seimon, A Sadler, FD … - Circulation, 2008 - Am Heart Assoc Methods and Results— Using both primary peritoneal macrophages and studies in advanced
atheromata in vivo, we introduce signal transducer and activator of transcription-1 (STAT1) as
a critical and necessary component of endoplasmic reticulum stress/type A scavenger ... Cited by 10 - Related articles - All 8 versions
