- ►diabetesjournals.org M van Hoek, A Dehghan, J Witteman, CM van Duijn, … - Diabetes, 2008 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—We investigated 18 polymorphisms from recent GWA
studies on type 2 diabetes in the Rotterdam Study, a prospective, population-based study among
homogeneous Caucasian individuals of 55 years and older (genotyped subjects, n = ... Cited by 33 - Related articles - All 4 versions
H Lango, CNA Palmer, AD Morris, E Zeggini, AT … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVES—Genome-wide association studies have dramatically increased the number of
common genetic variants that are robustly associated with type 2 diabetes. A possible clinical
use of this information is to identify individuals at high risk of developing the disease, so ... Cited by 28 - Related articles - All 5 versions
S Cauchi, D Meyre, E Durand, C Proença, M Marre, S … - PloS one, 2008 - pubmedcentral.nih.gov In the same French population analyzed in our previous GWA study (3,295 T2D and 3,595
NGT), strong associations with T2D were found for CDKAL1 (OR rs7756992 =
1.30[1.19–1.42], P = 2.3×10 −9 ), CDKN2A/2B (OR rs10811661 = 0.74[0.66–0.82], P = ... Cited by 21 - Related articles - All 7 versions
JB Meigs, P Shrader, LM Sullivan, JB … - The New England …, 2008 - nejm.highwire.org From the General Medicine Division (JB Meigs, PS), the Department of Medicine (JB Meigs,
PS, JCF), and the Center for Human Genetic Research and Diabe- tes Unit, Department of Medicine
(JB McAteer, JCF), Massachusetts General Hospital, Boston; the Department of Bio- ... Cited by 43 - Related articles - All 3 versions
- ►diabetesjournals.org M Vaxillaire, J Veslot, C Dina, C Proença, S Cauchi, G … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— The GCK (Glucokinase) −30A allele was associated with increased type 2 diabetes
risk at the end of the follow-up study (adjusted OR 1.34 [95% CI 1.07–1.69]) under an additive
model, as supported in independent French diabetic case subjects (OR 1.22, P = 0.007), ... Cited by 34 - Related articles - BL Direct - All 4 versions
- ►prsjournal.net ACJW Janssens, R Moonesinghe, Q Yang, EW … - Genetics in …, 2007 - journals.lww.com Purpose: Single genetic variants in multifactorial disorders typically have small effects, so major
increases in disease risk are expected only from the simultaneous exposure to multiple risk
genotypes. We investigated the impact of genotype frequencies on the clinical ... Cited by 21 - Related articles - BL Direct - All 7 versions
V Lyssenko, A Jonsson, P Almgren, N Pulizzi … - The New England …, 2008 - nejm.highwire.org From the Department of Clinical Sciences, Lund University, Malmö, Sweden (VL, AJ, PA, GB,
PN, LG); the University of Pisa, Pisa, Italy (NP); the Folkhalsan Research Center (BI, TT) and
Helsinki University Central Hospital and the Uni- versity of Helsinki (TT, LG) — all in ... Cited by 58 - Related articles - All 4 versions
- ►diabetesjournals.org [PDF] N Grarup, CS Rose, EA Andersson, G Andersen, AL … - Diabetes, 2007 - Am Diabetes Assoc Page 1. Studies of Association of Variants Near the HHEX, CDKN2A/B, and IGF2BP2
Genes With Type 2 Diabetes and Impaired Insulin Release in 10,705 Danish Subjects
Validation and Extension of Genome-Wide Association Studies ... Cited by 60 - Related articles - BL Direct - All 3 versions
N Grarup, G Andersen, NT Krarup, A Albrechtsen, O … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— Homozygous carriers of the minor diabetes risk G-allele of the CDC123/CAMK1D
rs12779790 showed an 18% decrease in insulinogenic index (95% CI 10–27%; P = 4 × 10
−5 ), an 18% decrease in corrected insulin response (CIR) (8.1–29%; P = 4 × 10 −4 ), and ... Cited by 16 - Related articles - All 6 versions
