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Scholar Results 1 - 10 of about 101 related to Barker: Two single nucleotide polymorphisms identify the highest-risk diabetes HLA genotype:.... (0.13 sec) 

Two single nucleotide polymorphisms identify the highest-risk diabetes HLA genotype: …

- diabetesjournals.org
JM Barker, TM Triolo, TA Aly, EE Baschal, SR … - Diabetes, 2008 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—SNPs rs2040410 and rs7454108 were associated with
DR3-DQB1*0201 and DR4-DQB1*0302. We correlated these SNPs with HLA genotypes and
with publicly available data on 5,019 subjects from the Type 1 Diabetes ...
Cited by 4 - Related articles - All 3 versions

Recent advances in coeliac disease genetics


KA Hunt, DA van Heel - British Medical Journal, 2009 - gut.bmj.com
Linkage studies have been highly successful in the search for susceptibility
loci in monogenic disorders but this success has not carried over into complex
diseases which are thought to arise due to multiple risk variants with ...
Cited by 1 - Related articles - All 2 versions

A high-throughput population screening system for the estimation of genetic risk for type 1 …


M Kiviniemi, R Hermann, J Nurmi, AG Ziegler, M … - Diabetes Technology & Therapeutics, 2007 - liebertonline.com
Page 1. 460 DIABETES TECHNOLOGY & THERAPEUTICS Volume 9, Number 5, 2007 ©
Mary Ann Liebert, Inc. DOI: 10.1089/dia.2007.0229 A High ...
Cited by 1 - Related articles - BL Direct - All 3 versions

The simultaneous presence of IL-1B and TNFA two-positions risk haplotypes enhances the …


AC Cherñavsky, MC Páez, N Periolo, P Correa, … - Cytokine, 2008 - Elsevier
To assess the joint contribution of interleukin 1 beta (IL-1B) and tumor
necrosis factor alpha (TNFα) to the genetic risk of developing celiac disease
(CD), we analyzed four biallelic polymorphisms of TNFA and IL-1B genes in ...
Cited by 1 - Related articles - All 4 versions

Changing Phenotype of Celiac Disease After Long-term Gluten Exposure


K Kurppa, O Koskinen, P Collin, M Mäki, T … - Journal of Pediatric Gastroenterology and Nutrition, 2008 - journals.lww.com
This study and the Celiac Disease Study Group are supported by the Academy of
Finland Research Council for Health, the Competitive Research Funding of the
Pirkanmaa Hospital District, the Yrjö Jahnsson Foundation, the Foundation ...
Cited by 1 - Related articles - All 2 versions

Intestinal T Cell Responses to Gluten Peptides Are Largely Heterogeneous: Implications …


A Camarca, RP Anderson, G Mamone, O Fierro, … - The Journal of Immunology, 2009 - Am Assoc Immnol
The identification of gluten peptides eliciting intestinal T cell responses is
crucial for the design of a peptide-based immunotherapy in celiac disease (CD).
To date, several gluten peptides have been identified to be active in CD. ...
Cited by 1 - Related articles - All 2 versions

Association between genetic variants in myosin IXB and Crohn's disease


R Cooney, JRF Cummings, S Pathan, J Beckly, … - Inflammatory Bowel Diseases, 2009 - interscience.wiley.com
Background: Genetic variation in myosin IXB (MYO9B) was found to be associated
with ulcerative colitis (UC) in a recent collaborative study. A nonsynonymous
single nucleotide polymorphism (SNP) rs1545620 at the 3 end of the gene was ...
Cited by 1 - Related articles - All 2 versions

Effective detection of human leukocyte antigen risk alleles in celiac disease using tag …


AJ Monsuur, PIW de Bakker, A Zhernakova, D … - Plos One, 2008 - pubmedcentral.nih.gov
The HLA genes, located in the MHC region on chromosome 6p21.3, play an important
role in many autoimmune disorders, such as celiac disease (CD), type 1 diabetes
(T1D), rheumatoid arthritis, multiple sclerosis, psoriasis and others. ...
Cited by 14 - Related articles - All 8 versions

A role for anti-transglutaminase 2 autoantibodies in the pathogenesis of coeliac disease?


K Lindfors, K Kaukinen, M Mäki - Amino Acids, 2009 - Springer
Abstract Coeliac disease is an autoimmune-mediated disorder with both innate and
adaptive immune compo- nents. The disease is triggered by dietary gluten, which
provokes the development of a massive immune reaction leading to the ...
Cited by 2 - Related articles - All 3 versions

Molecular diagnosis of celiac disease: are we there yet?


J Romanos, A Rybak, C Wijmenga, MC … - Expert Opin. Med. Diagn., 2008 - informahealthcare.com
Background: Celiac disease (CD) is a complex genetic disorder of the small
intestine resulting from aberrant cellular responses to gluten peptides. It may
affect as much as 1% of the Western population and the only treatment is a ...
Cited by 2 - Related articles - All 4 versions


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