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Scholar Results 1 - 10 of about 101 related to Lumeng: Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotem.... (0.09 sec) 

Phenotypic switching of adipose tissue macrophages with obesity is generated by …


CN Lumeng, JB DelProposto, DJ Westcott, AR … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—Resident ATMs in lean mice express the M2a marker macrophage galactose
N-acetyl-galactosamine specific lectin 1 (MGL1) and localize to interstitial
spaces between adipocytes independent of CCR2 and CCL2. With diet-induced ...
Cited by 16 - Related articles - All 3 versions

Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant …

- nih.gov
D Patsouris, PP Li, D Thapar, J Chapman, JM … - Cell metabolism, 2008 - Elsevier
Obese adipose tissue is characterized by infiltration of macrophages. We and
others recently showed that a specific subset of macrophages is recruited to
obese adipose and muscle tissue. This subset expresses CD11c and produces ...
Cited by 17 - Related articles - All 7 versions

Macrophage infiltration into adipose tissue: initiation, propagation and remodeling

- nih.gov
BK Surmi, AH Hasty - Future Lipidol., 2008 - Future Medicine
It has long been known that adipose tissue in obesity is in a heightened state
of inflammation. Recently, our understanding of this has been transformed by the
knowledge that immune cells such as macrophages and T cells can infiltrate ...
Cited by 5 - Related articles - All 5 versions

Preadipocyte apoptosis is prevented by macrophage-conditioned medium in a PDGF- …


ASD Molgat, AM Gagnon, A Sorisky - American Journal of Physiology- Cell Physiology, 2009 - Am Physiological Soc
Obesity is associated with macrophage accumulation and inflammation in adipose
tissue. Macrophage-secreted factors have been reported to inhibit the
differentiation of preadipocytes into adipocytes and to modulate adipogenic ...
Cited by 1 - Related articles - All 3 versions

n-3 Fatty acids and rosiglitazone improve insulin sensitivity through additive stimulatory …


O Kuda, T Jelenik, Z Jilkova, P Flachs, M … - Diabetologia, 2009 - Springer
Page 1. ARTICLE n-3 Fatty acids and rosiglitazone improve insulin sensitivity
through additive stimulatory effects on muscle glycogen ...
Cited by 2 - Related articles - All 4 versions

Remodeling phenotype of human subcutaneous adipose tissue macrophages

- ahajournals.org
V Bourlier, A Zakaroff-Girard, A Miranville, … - Circulation, 2008 - Am Heart Assoc
Methods and Results— The present study, performed on human subcutaneous AT,
showed that ATMs from lean to overweight individuals are composed of distinct
macrophage subsets based on the expression of several cell surface markers: ...
Cited by 40 - Related articles - All 6 versions

Dead adipocytes, detected as crown-like structures, are prevalent in visceral fat depots of …

- jlr.org
I Murano, G Barbatelli, V Parisani, C Latini, G … - The Journal of Lipid Research, 2008 - ASBMB
Accumulation of visceral fat is a key phenomenon in the onset of
obesity-associated metabolic disorders. Macrophage infiltration induces chronic
mild inflammation widely considered as a causative factor for insulin ...
Cited by 20 - Related articles - All 5 versions

Insulin sensitivity: modulation by nutrients and inflammation


S Schenk, M Saberi, JM Olefsky - The Journal of Clinical Investigation, 2008 - pubmedcentral.nih.gov
Insulin resistance is a major metabolic feature of obesity and is a key factor
in the etiology of a number of diseases, including type 2 diabetes. In this
review, we discuss potential mechanisms by which brief nutrient excess and ...
Cited by 46 - Related articles - All 12 versions

Muscle inflammatory response and insulin resistance: synergistic interaction between …


V Varma, A Yao-Borengasser, N Rasouli, GT … - American Journal of Physiology- Endocrinology And …, 2009 - Am Physiological Soc
Obesity is characterized by adipose tissue expansion as well as macrophage
infiltration of adipose tissue. This results in an increase in circulating
inflammatory cytokines and nonesterified fatty acids, factors that cause ...
Cited by 3 - Related articles - All 3 versions

Peroxisome proliferator-activated receptor {gamma} activation promotes infiltration of …

- jbc.org
R Stienstra, C Duval, S Keshtkar, J van der … - Journal of Biological Chemistry, 2008 - ASBMB
Obesity is associated with infiltration of macrophages into adipose tissue.
Adipose macrophages may contribute to an elevated inflammatory status by
secreting a variety of proinflammatory mediators, including tumor necrosis ...
Cited by 13 - Related articles - All 6 versions


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