J Krakoff, L Ma, S Kobes, WC Knowler, RL … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Among the 3,074 subjects, 43 were heterozygous for R165Q and 14 for
NT100 (frequency = 0.007 and 0.002). Mean (± SD) BMI was higher among subjects
with R165Q (39.3 ± 8.6 kg/m 2 ) or NT100 (41.2 ± 7.8) than subjects ... Cited by 6 - Related articles - All 4 versions
T Wangensteen, ML Kolsgaard, M Mattingsdal, … - Exp Clin Endocrinol Diabetes, 2009 - thieme-connect.com Results: Nine mutations were identified, of which four were novel and five
previously described. The prevalence of MC4R mutations was 1.6% in pediatric and
0.8% in adult patients. All four novel mutations, I69R, M79I, I195S, and ... Cited by 2 - Related articles - All 3 versions
ZC Fan, YX Tao - Journal of Cellular and Molecular Medicine, 2009 - interscience.wiley.com As the most common monogenic form of human obesity, about 130 naturally
occurring melanocortin-4 receptor (MC4R) gene mutations have been identified. In
this study, we reported detailed functional characterization of ten novel ... Cited by 2 - Related articles - All 2 versions
K Valli-Jaakola, JJ Palvimo, M Lipsanen- … - Horm Res, 2006 - content.karger.com Background/Aims: Mutations in melanocortin-4 receptor (MC4R) are the most common
genetic cause of human obesity. Mutations in MC4R promoter could also underlie
obesity, but have so far not been reported. Transcription factor nescient ... Cited by 7 - Related articles - BL Direct - All 8 versions
A Bosy-Westphal, MJ Müller, M Boschmann, S … - British Journal of Nutrition, 2008 - Cambridge Univ Press Page 1. Short Communication Grade of adiposity affects the impact of fat mass
on resting energy expenditure in women Anja Bosy-Westphal ... Cited by 3 - Related articles - All 4 versions
CL Roth, M Ludwig, J Woelfle, ZC Fan, H … - Endocrine, 2009 - Springer Abstract This study targeted the identification of muta- tions of melanocortin-4
receptor gene (MC4R) in obese children. Fifty-one unrelated probands with early
onset severe obesity (body mass index (BMI) [99th percentile; 21 girls, ... Cited by 3 - Related articles - All 2 versions
R Rong, YX Tao, BM Cheung, A Xu, GC … - CLINICAL ENDOCRINOLOGY-OXFORD-, 2006 - cvm-wwwdev.vetmed.auburn.edu Objective Mutations in the melanocortin-4 receptor gene (MC4R) are the most
common monogenic form of human obesity. However, the contribution of MC4R
mutations to obesity in Chinese has not been investigated. We studied the ... Cited by 15 - Related articles - View as HTML - BL Direct - All 7 versions
- ►diabetesjournals.org F Stutzmann, K Tan, V Vatin, C Dina, B Jouret, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— Of the MC4R nonsynonymous mutations found in obese subjects, 68%
resulted in a loss of function in vitro. They were found in 1.72% of obese
versus 0.15% of nonobesed subjects (P = 6.9 × 10 −10 ). Among the ... Cited by 10 - Related articles - All 5 versions
[CITATION] Study of body composition: an overview
W Shen, MP St-Onge, Z Wang, SB Heymsfield - Human Body Composition, 2nd edn Human Kinetics: …, 2005 Cited by 4 - Related articles
YS Lee, LK Poh, BL Kek, KY Loke - CLINICAL ENDOCRINOLOGY-OXFORD-, 2008 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 4 - Related articles - BL Direct - All 3 versions
