JX Chen, A Stinnett - Diabetes, 2008 - Am Diabetes Assoc RESULTS— Systemic administration of Ad-CMV-Ang-1 results in overexpression of
Ang-1 in db/db mice hearts. Ang-1 gene therapy causes a significant increase in
Akt and eNOS expression and HIF-1α stabilization. This is accompanied by a ... Cited by 2 - Related articles - All 3 versions
T Yamashita, K Ohneda, M Nagano, C Miyoshi … - Journal of Biological Chemistry, 2008 - ASBMB 1 Department of Regenerative Medicine, 2 Department of Molecular and
Developmental Biology, 3 Center for Tsukuba Advanced Research Alliance, ...
Project, 5 Department of Molecular Pharmacology and 6 JST-SORST Project, ... Cited by 3 - Related articles - All 3 versions
GL Semenza - Seminars in cancer biology, 2009 - Elsevier The induction of hypoxia-inducible factor 1 (HIF-1) activity, either as a result
of intratumoral hypoxia or loss-of-function mutations in the VHL gene, leads to
a dramatic reprogramming of cancer cell metabolism involving increased ... Cited by 7 - Related articles - All 4 versions
I Helfrich, L Edler, A Sucker, M Thomas, S … - Clinical Cancer Research, 2009 - AACR Results: Circulating levels of sAng-2 correlate with tumor progression in
melanoma patients (P < 0.0001) and patient survival (P = 0.007). Analysis of
serum samples during the transition from stage III to IV identified an ... Cited by 4 - Related articles - All 3 versions
O Aprelikova, S Pandolfi, S Tackett, M … - Cancer Research, 2009 - AACR During tumor growth, delayed blood vessel expansion is responsible for the
limited amount of oxygen and glucose required for tumor growth. Tumors adapt to
this condition by rapidly stabilizing hypoxia-inducible factors ... Cited by 5 - Related articles - All 2 versions
HM Yang, CK Lai, J Patel, J Moore, PS Chen, … - Cardiovascular Pathology, 2007 - Elsevier A 55-year-old man with a history of paroxysmal atrial fibrillation refractory to
antiarrhythmic medication had radiofrequency ablation in April 2003 and July
2003. Although these procedures were successful in resolving the patient's ... Cited by 5 - Related articles - All 8 versions
- ►ahajournals.org JX Chen, A Stinnett - Arteriosclerosis, Thrombosis, and Vascular Biology, 2008 - Am Heart Assoc Methods and Results— Tie-2 expression was significantly attenuated, whereas
angiopoietin-2 (Ang-2) was increased in db/db mice subjected to myocardial
ischemia. Our morphological analysis showed that the number of SMC coverage ... Cited by 5 - Related articles - All 4 versions
- ►physiology.org Q Tuo, H Zeng, A Stinnett, H Yu, JL Aschner, … - American Journal of Physiology- Heart and Circulatory …, 2008 - Am Physiological Soc Angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2) are the two ligands of the
Tie-2 receptor, a receptor tyrosine kinase that is expressed on the endothelium.
A balanced angiopoietin/Tie-2 system is critical for the maintenance of ... Cited by 6 - Related articles - All 3 versions
