- ►diabetesjournals.org S Weksler-Zangen, I Raz, S Lenzen, A Jörns, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Hyperglycemic Cohen diabetes–sensitive rats exhibited reduced
pancreatic weight with lipid deposits and interleukin-1β–positive macrophage
infiltration in the exocrine pancreas. Islet morphology was preserved, and ... Cited by 9 - Related articles - BL Direct - All 3 versions
[CITATION] IL-1β-MyD88 signaling is central to islet chemokine secretion in response to metabolic …
- ►endojournals.org P Ribaux, JA Ehses, N Lin-Marq, F … - Endocrinology, 2007 - Endocrine Soc As we showed previously, the extracellular matrix (ECM) derived from rat bladder
carcinoma cells (804G-ECM) has positive effects on rat primary β-cell function
and survival in vitro. The aim of this study was to define β-cell genes ... Cited by 13 - Related articles - BL Direct - All 4 versions
- ►endojournals.org [PDF] M Boni-Schnetzler, J Thorne, G Parnaud, L … - Journal of Clinical Endocrinology & Metabolism, 2008 - Endocrine Soc 1 Clinic of Endocrinology and Diabetes, University Hospital of Zurich, 8091
Zurich, Switzerland 2 Section of Islet Transplantation and Cell Biology, Joslin
Diabetes Center, Harvard Medical School, Boston, Massachusetts 02215, USA 3 ... Cited by 1 - Related articles
- ►endojournals.org M Boni-Schnetzler, J Thorne, G Parnaud, L … - Journal of Clinical Endocrinology & Metabolism, 2008 - Endocrine Soc Results: Gene array analysis of RNA from β-cells of individuals with T2DM
revealed increased expression of IL-1β mRNA. Real-time PCR confirmed increased
IL-1β expression in six of 10 T2DM samples, with minimal or no expression ... Cited by 8 - Related articles - All 4 versions
A Jörns, KJ Rath, O Bock, S Lenzen - Diabetologia, 2006 - Springer Abstract Aims/hypothesis It has recently been proposed that IL-1β may be
responsible for beta cell death in type 2 diabetes mellitus. Major support for
this assumption was derived from experiments in the gerbil Psammomys obesus ... Cited by 11 - Related articles - All 4 versions
O Osborn, SE Brownell, M Sanchez-Alavez, D … - Cytokine, 2008 - Elsevier The proinflammatory cytokine Interleukin 1 beta (IL-1β) is elevated in obese
individuals and rodents and it is implicated in impaired insulin secretion,
decreased cell proliferation and apoptosis of pancreatic beta cells. In ... Cited by 7 - Related articles - All 3 versions
K Maedler, G Dharmadhikari, DM Schumann, J … - Expert Opin. Biol. Ther., 2009 - informahealthcare.com Since having been cloned in 1984, IL-1β has been the subject of over 22,000
citations in Pubmed, among them over 800 reviews. This is because of its
numerous effects. IL-1β is a regulator of the body's inflammatory response ... Related articles - All 6 versions