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Scholar Results 1 - 10 of about 101 related to Weksler-Zangen: Impaired glucose-stimulated insulin secretion is coupled with exocrine pancreatic.... (0.11 sec) 

Impaired glucose-stimulated insulin secretion is coupled with exocrine pancreatic lesions in …

- diabetesjournals.org
S Weksler-Zangen, I Raz, S Lenzen, A Jörns, … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—Hyperglycemic Cohen diabetes–sensitive rats exhibited reduced
pancreatic weight with lipid deposits and interleukin-1β–positive macrophage
infiltration in the exocrine pancreas. Islet morphology was preserved, and ...
Cited by 9 - Related articles - BL Direct - All 3 versions

[CITATION] IL-1β-MyD88 signaling is central to islet chemokine secretion in response to metabolic …


JA Ehses, MH Giroix, J Coulaud, S Akira, F … - Diabetologia, 2008
Cited by 3 - Related articles

Induction of CXCL1 by Extracellular Matrix and Autocrine Enhancement by Interleukin-1 in …

- endojournals.org
P Ribaux, JA Ehses, N Lin-Marq, F … - Endocrinology, 2007 - Endocrine Soc
As we showed previously, the extracellular matrix (ECM) derived from rat bladder
carcinoma cells (804G-ECM) has positive effects on rat primary β-cell function
and survival in vitro. The aim of this study was to define β-cell genes ...
Cited by 13 - Related articles - BL Direct - All 4 versions

Increased IL-1 {beta} mRNA expression in {beta}-cells of individuals with type 2 diabetes and …

- endojournals.org [PDF] 
M Boni-Schnetzler, J Thorne, G Parnaud, L … - Journal of Clinical Endocrinology & Metabolism, 2008 - Endocrine Soc
1 Clinic of Endocrinology and Diabetes, University Hospital of Zurich, 8091
Zurich, Switzerland 2 Section of Islet Transplantation and Cell Biology, Joslin
Diabetes Center, Harvard Medical School, Boston, Massachusetts 02215, USA 3 ...
Cited by 1 - Related articles

Increased Interleukin (IL)-1 {beta} Messenger Ribonucleic Acid Expression in {beta}-Cells of …

- endojournals.org
M Boni-Schnetzler, J Thorne, G Parnaud, L … - Journal of Clinical Endocrinology & Metabolism, 2008 - Endocrine Soc
Results: Gene array analysis of RNA from β-cells of individuals with T2DM
revealed increased expression of IL-1β mRNA. Real-time PCR confirmed increased
IL-1β expression in six of 10 T2DM samples, with minimal or no expression ...
Cited by 8 - Related articles - All 4 versions

[CITATION] Is anti-inflammatory therapy for type 2 diabetes mellitus ready for routine clinical practice?


NA Maybee, BB Worrall, JL Nadler - Nature clinical practice. Endocrinology & metabolism, 2007 - ncbi.nlm.nih.gov
1: Nat Clin Pract Endocrinol Metab. 2007 Dec;3(12):806-7. Epub 2007 Sep
18. Comment on: N Engl J Med. 2007 Apr 12;356(15):1517-26. ...
Cited by 2 - Related articles - BL Direct - All 3 versions

Beta cell death in hyperglycaemic Psammomys obesus is not cytokine-mediated


A Jörns, KJ Rath, O Bock, S Lenzen - Diabetologia, 2006 - Springer
Abstract Aims/hypothesis It has recently been proposed that IL-1β may be
responsible for beta cell death in type 2 diabetes mellitus. Major support for
this assumption was derived from experiments in the gerbil Psammomys obesus ...
Cited by 11 - Related articles - All 4 versions

Treatment with an Interleukin 1 beta antibody improves glycemic control in diet-induced …


O Osborn, SE Brownell, M Sanchez-Alavez, D … - Cytokine, 2008 - Elsevier
The proinflammatory cytokine Interleukin 1 beta (IL-1β) is elevated in obese
individuals and rodents and it is implicated in impaired insulin secretion,
decreased cell proliferation and apoptosis of pancreatic beta cells. In ...
Cited by 7 - Related articles - All 3 versions

[CITATION] Development of the model


AM Cohen - The Cohen diabetic rat, 1990
Cited by 8 - Related articles

Interleukin-1 beta targeted therapy for type 2 diabetes


K Maedler, G Dharmadhikari, DM Schumann, J … - Expert Opin. Biol. Ther., 2009 - informahealthcare.com
Since having been cloned in 1984, IL-1β has been the subject of over 22,000
citations in Pubmed, among them over 800 reviews. This is because of its
numerous effects. IL-1β is a regulator of the body's inflammatory response ...
Related articles - All 6 versions


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