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Insulin action in the double incretin receptor knockout mouse

- glucagon.com [PDF] 
JE Ayala, DP Bracy, T Hansotia, G Flock, Y … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—Compared with wild-type mice, chow and high fat–fed DIRKO mice
exhibited decreased fat and muscle mass associated with increased energy
expenditure and ambulatory activity. Clamp rates of glucose infusion (GIR), ...
Cited by 9 - Related articles - BL Direct - All 5 versions

The effect of somatostatin on fasting and postprandial plasma GIP, serum insulin, and blood …


R Jorde, HL Waldum, PG Burhol, I Lygren, TB … - Scandinavian journal of gastroenterology, 1981 - ncbi.nlm.nih.gov
Six healthy men were given a standard breakfast, one day with and another day
without a 2-h 100 micrograms/h somatostatin infusion. During the somatostatin
infusion the meal-induced responses of plasma GIP and serum insulin were ...
Cited by 5 - Related articles

Incretin receptors for glucagon-like peptide 1 and glucose-dependent insulinotropic …

- diabetesjournals.org
G Flock, LL Baggio, C Longuet, DJ Drucker - Diabetes, 2007 - Am Diabetes Assoc
RESULTS—Vildagliptin had no significant effect on food intake, energy
expenditure, body composition, body weight gain, or insulin sensitivity in WT or
DIRKO mice. However, glycemic excursion after oral glucose challenge was ...
Cited by 12 - Related articles - BL Direct - All 4 versions

Effect of somatostatin on fasting and glucose-stimulated gastric inhibitory polypeptide …


M Salera, L Pironi, P Giacomoni, S Venturi, M … - Digestion, 1982 - content.karger.com
The effect of intravenous somatostatin infusion on circulating gastric
inhibitory polypeptide (GIP), insulin, glucagon and on blood glucose was
investigated in 7 healthy volunteers in the fasting state and during the ...
Cited by 6 - Related articles - All 4 versions

Effects of GLP-1 and 2, 5-anhydro-D-mannitol on insulin secretion and plasma glucose in …


B Ahren, S Lindskog, G Van Dijk, AJ Scheurink … - Endocrine research, 1995 - ncbi.nlm.nih.gov
The truncated glucagon-like peptide-1 (GLP-1(7-36)amide or GLP-1) stimulates
insulin secretion, enhances glucose elimination and is of potential interest in
diabetes treatment. We studied the hypoglycemic action of GLP-1 in normal ...
Cited by 7 - Related articles - BL Direct - All 3 versions

Measurements of islet function and glucose metabolism with the dipeptidyl peptidase 4 …

- endojournals.org
K Azuma, Z Radikova, J Mancino, FGS Toledo, … - Journal of Clinical Endocrinology & Metabolism, 2008 - Endocrine Soc
Objective: Pharmacological inhibition with the dipeptidyl peptidase 4 (DPP-4)
inhibitor vildagliptin prolongs the action of endogenously secreted incretin
hormones leading to improved glycemic control in patients with type 2 ...
Cited by 24 - Related articles - BL Direct - All 4 versions

Differential Antidiabetic Efficacy of Incretin Agonists Versus DPP-4 Inhibition in High Fat– …

- diabetesjournals.org
BJ Lamont, DJ Drucker - Diabetes, 2008 - Am Diabetes Assoc
RESULTS AND CONCLUSIONS— Mice treated with vehicle alone or DA-GIP exhibited
progressive weight gain, whereas treatment with Ex-4 or DPP-4i prevented weight
gain. Although Ex-4 improved oral glucose tolerance and insulin-to-glucose ...
Cited by 17 - Related articles - BL Direct - All 5 versions

Effects of glucagon-like peptide-I on glucose turnover in rats


G Van Dijk, S Lindskog, JJ Holst, AB Steffens, … - American Journal of Physiology- Endocrinology And …, 1996 - Am Physiological Soc
Van Dijk, Gertjan, Stefan Lindskog, Jens J. Holst, Anton B. Steffens, and Bo
Ahrh. Effects of glucagon-like peptide- on glucose turnover in rats. Am. J.
Physiol. 270 (EndocrinoZ. Metab. 33): El015-El021, 1996.-The influ-
Cited by 17 - Related articles - BL Direct - All 4 versions

[PDF] Endocrinology. First published ahead of print September 18, 2008 as doi: 10.1210/en. 2008 …


H Duez, AC Smith, C Xiao, A Giacca, L Szeto, … - glucagon.com
Page 1. 1 Acute DPP-4 Inhibition rapidly Enhances Insulin-mediated
Suppression of Endogenous Glucose Production in Mice Hélène ...
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Acute Dipeptidyl Peptidase-4 Inhibition Rapidly Enhances Insulin-Mediated Suppression …

- glucagon.com [PDF] 
H Duez, AC Smith, C Xiao, A Giacca, L Szeto, … - Endocrinology, 2009 - Endocrine Soc
Pharmacological approaches that enhance incretin action for the treatment of
type 2 diabetes mellitus have recently been developed, ie. injectable
glucagon-like peptide-1 receptor (GLP-1R) agonists with prolonged plasma ...
Related articles - All 3 versions


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