HPMM Lauritzen, H Galbo, J Brandauer, LJ Goodyear, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—During the first 30 min of insulin stimulation, very few superficially or deeply located
GLUT4 storage vesicles (>1 μm) moved in toto. Rather, big vesicles were stationary in their original
position at sarcolemma or t-tubules and were locally depleted of GLUT4 by budding off of ... Cited by 7 - Related articles - BL Direct - All 4 versions
JD Schertzer, CN Antonescu, PJ Bilan, S Jain, X Huang … - Endocrinology, 2009 - Endocrine Soc Skeletal muscle is the major site for dietary glucose disposal, taking up glucose via glucose transporter
4 (GLUT4). Although subcellular fractionation studies demonstrate that insulin increases GLUT4
density in sarcolemma and transverse tubules, fractionation cannot discern GLUT4 ... Cited by 4 - Related articles - All 3 versions
- ►biologists.org DJ Fazakerley, SP Lawrence, VA Lizunov, SW … - Journal of Cell …, 2009 - jcs.biologists.org A new mouse model has been developed to study the localisation and trafficking of the glucose
transporter GLUT4 in muscle. The mouse line has specific expression of a GFP and
HA-epitope-tagged version of GLUT4 under the control of a muscle-specific promoter. ... Cited by 5 - Related articles - All 7 versions
A Klip, JD Schertzer, PJ Bilan, F Thong, C … - Acta Physiol.( …, 2009 - interscience.wiley.com Skeletal muscle is the major store and consumer of fatty acids and glucose. Glucose enters muscle
through glucose transporter 4 (GLUT4). Upon insufficient oxygen availability or energy
compromise, aerobic metabolism of glucose and fatty aids cannot proceed, and muscle ... Cited by 1 - Related articles - All 3 versions
- ►physiology.org EJ Miller, J Li, KM Sinusas, GD Holman, … - American Journal of …, 2007 - Am Physiological Soc Glucose uptake in the heart is mediated by specific glucose transporters (GLUTs) present on
cardiomyocyte cell surface membranes. Metabolic stress and insulin both increase glucose transport
by stimulating the translocation of glucose transporters from intracellular storage vesicles ... Cited by 2 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org HPM Lauritzen, T Ploug, H Ai, M Donsmark, C Prats, H … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Denervation and high-fat diet reduced insulin-mediated glucose transport. In denervated
muscle, insulin-stimulated phosphatidylinositol 3,4,5 P 3 (PIP3) production was abolished in
T-tubules, while PIP3 production at sarcolemma was increased 2.6-fold. Correspondingly, ... Cited by 3 - Related articles - BL Direct - All 3 versions
HPMM Lauritzen¹, H Galbo, J Brandauer, LJ Goodyear, … - Am Diabetes Assoc ¹ Research Division, Joslin Diabetes Center and Harvard Medical School, Boston, MA
02215, USA. 2Department of Rheumatology, Bispebjerg Hospital, DK-2400, Copenhagen
NV, Denmark. 3Copenhagen Muscle Research Centre, Department of Medical ... Related articles
HPMM Lauritzen, H Galbo, J Brandauer, LJ Goodyear, … - DIABETES, 2008 - Am Diabetes Assoc Large GLUT4 Vesicles Are Stationary While Locally and ... Imaging Analysis of GLUT4–Enhanced
Green Fluorescent ... Hans PMM Lauritzen, 1 Henrik Galbo, 2 Josef Brandauer, 1 Laurie J.
Goodyear, 1 and Thorkil Ploug 3 ... OBJECTIVE—Insulin stimulates glucose transport in ... Related articles
- ►diabetesjournals.org HPMM Lauritzen, T Ploug, C Prats, JM Tavaré, H Galbo - Diabetes, 2006 - Am Diabetes Assoc Insulin stimulates glucose transport in skeletal muscle by glucose transporter GLUT4 translocation
to sarcolemma and membrane invaginations, the t-tubules. Although muscle glucose uptake
plays a key role in insulin resistance and type 2 diabetes, the dynamics of GLUT4 ... Cited by 21 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org HKR Karlsson, AV Chibalin, HA Koistinen, J Yang, F … - Diabetes, 2009 - Am Diabetes Assoc OBJECTIVE In skeletal muscle, insulin stimulates glucose transport activity three- to fourfold,
and a large part of this stimulation is associated with a net translocation of GLUT4 from an intracellular
compartment to the cell surface. We examined the extent to which insulin or the AMP- ... Cited by 5 - Related articles - All 5 versions
