- ►diabetesjournals.org S Zhang, H Liu, H Yu, GJS Cooper - Diabetes, 2008 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS— We measured responses to hA in isolated mouse
islets and two insulinoma cell lines, wherein we measured Fas/Fas ligand (FasL)
and Fas-associated death domain (FADD) expression by quantitative RT-PCR, ... Cited by 5 - Related articles - BL Direct - All 3 versions
JA Bernal - diabetes.org.ar Page 1. Análisis molecular de la disfunción de la célula β pancreática
en la progresión de la diabetes tipo 2. Su aplicación ... Related articles - View as HTML
Y Zhang, F Ranta, C Tang, E Shumilina, H … - Apoptosis, 2009 - Springer Abstract Amyloid peptides interfere with survival of pancreatic beta-cells. In
some cells apoptosis is paralleled by ceramide-dependent alterations of ion
channel activity. The purpose of the present study was to elucidate the ... Related articles - All 2 versions
- ►diabetesjournals.org CY Lin, T Gurlo, R Kayed, AE Butler, L … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE—Islets in type 2 diabetes are characterized by a deficit in
β-cells, increased β-cell apoptosis, and islet amyloid derived from islet
amyloid polypeptide (IAPP). The toxic form of amyloidogenic protein ... Cited by 23 - Related articles - BL Direct - All 5 versions
S Zhang, H Liu, J Liu, CA Tse, M Dragunow, … - FEBS JOURNAL, 2006 - interscience.wiley.com Amylin-mediated islet β-cell death is implicated in diabetogenesis. We
previously reported that fibrillogenic human amylin (hA) evokes β-cell
apoptosis through linked activation of Jun N-terminal kinase 1 (JNK 1) and ... Cited by 14 - Related articles - BL Direct - All 4 versions
LL Atkinson, C McDonald-Dyck, C Benkoczi, … - Diabetes, Obesity and Metabolism, 2008 - interscience.wiley.com Here we investigate the effect of rosiglitazone (RSG), metformin (MET) and
glyburide (GLIB) on plasma glucose levels, β-cell mass, function and insulin
sensitivity in 10-week-old diabetic male Zucker diabetic fatty (mZDF) rats ... Cited by 1 - Related articles - All 2 versions
M Tiedge - Deutsche medizinische Wochenschrift (1946), 2006 - ncbi.nlm.nih.gov Using the metabolic stimulus-secretion coupling of pancreatic beta cells as an
example, this review illustrates how new strategies in the treatment of type 2
diabetes mellitus can be developed from the results of basic research. ... Cited by 1 - Related articles - BL Direct
HL Zhao, Y Sui, J Guan, L He, XM Gu, HK … - Translational Research, 2009 - Elsevier The amyloid hypothesis of type 2 diabetes mellitus postulates that elevated
levels of normally expressed monomeric proteins of human islet amyloid
polypeptide (hIAPP) trigger oligomerization that independently causes ... Cited by 1 - Related articles - All 12 versions
S Bonner-Weir, TD O'Brien - Diabetes, 2008 - Am Diabetes Assoc The UK Prospective Diabetes Study (UKPDS) orchestrated by Robert Turner showed
that, even with treatment, in type 2 diabetes a progressive β-cell dysfunction
in a large number of patients was seen with the eventual need for ... Cited by 2 - Related articles - All 3 versions
- ►nih.gov WPS Wong, DW Scott, CL Chuang, S Zhang, H … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Diabetes occurred in hemizygous human amylin transgenic mice from 6
weeks after birth. Glucose tolerance was impaired during the mid- and
end-diabetic phases, in which progressive β-cell loss paralleled ... Cited by 2 - Related articles - All 4 versions
