K Højlund, D Glintborg, NR Andersen, JB Birk, JT … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— Impaired insulin-mediated total (R d ) oxidative and nonoxidative glucose disposal
(NOGD) was paralleled by reduced insulin-stimulated Akt phosphorylation at Ser473 and Thr308
and AS160 phosphorylation in muscle of PCOS patients. Akt phosphorylation at Ser473 ... Cited by 17 - Related articles - BL Direct - All 3 versions
- ►endojournals.org D Glintborg, K Hojlund, NR Andersen, BF … - Journal of Clinical …, 2008 - Endocrine Soc Results: Reduced insulin-mediated glucose disposal (P < 0.05) was associated with a lower
insulin-stimulated GS activity in PCOS patients (P < 0.05), compared with controls. This was,
in part, explained by absent insulin-mediated dephosphorylation of GS at the NH 2 ... Cited by 3 - Related articles - All 3 versions
YL Chu, YY Sun, HY Qiu, HF Li - Zhonghua fu chan ke za zhi, 2004 - ncbi.nlm.nih.gov OBJECTIVE: To investigate the tyrosine phosphorylation and protein expression of insulin receptor
substrate-1 in adipose tissue from patients with polycystic ovary syndrome, and explore molecular
mechanisms of insulin resistance of PCOS. METHODS: Samples from patients with PCOS ... Cited by 8 - Related articles - BL Direct
HY Qiu, YL Chu, M Li, YY Sun, HF Li - Zhonghua fu chan ke za zhi, 2005 - ncbi.nlm.nih.gov OBJECTIVE: To explore molecular mechanisms of insulin resistance of polycystic ovary syndrome
(PCOS) by determining the tyrosine phosphorylation and protein expression of insulin receptor
substrate-2 (IRS-2) in adipose tissue from patients with PCOS. METHODS: Serum and ... Cited by 4 - Related articles
K Højlund, JFP Wojtaszewski, J Birk, BF Hansen, H … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis Recently we reported the coexistence of postprandial hypoglycaemia
and moderate insulin resis- tance in heterozygous carriers of the Arg1174Gln mutation in the
insulin receptor gene (INSR). Controlled studies of in vivo insulin signalling in humans ... Cited by 5 - Related articles - BL Direct - All 3 versions
K Hojlund, H Beck-Nielsen - Current Diabetes Reviews, 2006 - ingentaconnect.com Abstract: Insulin resistance in skeletal muscle is a major hallmark of type 2 diabetes and an early
detectable abnormality in the development of this disease. The cellular mechanisms of insulin
resistance include impaired insulin-mediated muscle glycogen synthesis and increased ... Cited by 7 - Related articles - BL Direct - All 2 versions
C Prats, JW Helge, P Nordby, K Qvortrup, T Ploug, … - Journal of Biological …, 2009 - ASBMB Glycogen synthase (GS) is considered the rate-limiting enzyme in glycogenesis but still today
there is a lack of understanding on its regulation. We have previously shown
phosphorylation-dependent GS intracellular redistribution at the start of glycogen re- ... Cited by 1 - Related articles - All 3 versions
[CITATION] Dysregulation of GSK3B activity in polycystic ovarian syndrome (PCOS) theca: a …
I Munir, DH Geller, CE deBruin, DA Magoffin - Proceedings of the 88th Annual Meeting …, 2006 Cited by 2 - Related articles
V Skov, D Glintborg, S Knudsen, Q Tan, T Jensen, … - PLoS ONE, 2008 - pubmedcentral.nih.gov Insulin resistance is a common metabolic abnormality in women with PCOS and leads to an
elevated risk of type 2 diabetes. Studies have shown that thiazolidinediones (TZDs) improve
metabolic disturbances in PCOS patients. We hypothesized that the effect of TZDs in ... Cited by 3 - Related articles - All 6 versions
D Glintborg, AP Hermann, M Andersen, C Hagen, H … - Fertility and sterility, 2006 - Elsevier To thoroughly examine the mechanisms for insulin resistance in polycystic ovary syndrome
(PCOS) and to evaluate the effects of pioglitazone treatment on insulin resistance, β-cell
function, LH secretion, and glucose metabolism. ... Outpatient clinic, at a university ... Cited by 22 - Related articles - All 10 versions
