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Scholar Results 1 - 10 of about 101 related to Martin: Islet expression of M3 uncovers a key role for chemokines in the development and.... (0.13 sec) 

Islet expression of M3 uncovers a key role for chemokines in the development and …


AP Martin, MG Grisotto, C Canasto-Chibuque, … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—Multiple chemokines were expressed in pancreatic islets of NOD mice
before development of diabetes. Islet-specific expression of the pan-chemokine
inhibitor M3 dramatically reduced leukocyte infiltration and islet ...
Cited by 5 - Related articles - BL Direct - All 4 versions

The chemokine decoy receptor M3 blocks CC chemokine ligand 2 and CXC chemokine ligand …

- jimmunol.org
AP Martin, C Canasto-Chibuque, L Shang, BJ … - The Journal of Immunology, 2006 - Am Assoc Immnol
Chemokines and their receptors play a key role in immune homeostasis regulating
leukocyte migration, differentiation, and function. Viruses have acquired and
optimized molecules that interact with the chemokine system. These ...
Cited by 11 - Related articles - BL Direct - All 6 versions

The chemokine binding protein M3 prevents diabetes induced by multiple low doses of …

- jimmunol.org
AP Martin, JM Alexander-Brett, C Canasto- … - The Journal of Immunology, 2007 - Am Assoc Immnol
Multiple injections of low-dose streptozotocin (MLDS) induce lymphocytic
insulitis and diabetes in rodents. To test whether the influx of inflammatory
cells was associated with changes in the expression of chemokines, we ...
Cited by 13 - Related articles - All 6 versions

Animal models of autoimmune polyglandular syndrome


H Ikegami - Endocrinology and metabolism clinics of North America, 2002 - Elsevier
Autoimmune polyglandular syndrome is characterized by the association of two or
more organ-specific autoimmune disorders [1]. Four distinct types of autoimmune
polyglandular syndrome have been described ( Table 1) [2].
Cited by 5 - Related articles - BL Direct - All 4 versions

CCR7 Deficiency in NOD Mice Leads to Thyroiditis and Primary Hypothyroidism


AP Martin, T Marinkovic, C Canasto-Chibuque, … - The Journal of Immunology, 2009 - Am Assoc Immnol
CCR7 is involved in the initiation of immune responses and has been recently
implicated in the control of tolerance. To analyze the role of CCR7 in
autoimmunity, we backcrossed CCR7 ko/ko mice (in which ko signifies ...
Related articles - All 3 versions

The Chemokine-Binding Protein M3 as a Tool to Understand the Chemokine Network In …


SA Lira, A Viejo-Borbolla, L Shang, AP Martin - Chemokines, 2009 - books.google.com
> CHAPTER NINE > The Chemokine-Binding Protein M3 as a Tool to Understand the
Chemokine Network In Vivo Sergio A. Lira,* Abel Viejo-Borbolla,*,† Limin
Shang,* and Andrea P. Martin* Contents 1. Introduction 193 2. Generation of ...
Related articles - All 2 versions

Expression of the Chemokine Binding Protein M3 Promotes Marked Changes in the …


L Shang, N Thirunarayanan, A Viejo– … - Gastroenterology, 2009 - Elsevier
We observed distinct chemokine expression profiles in the 6 segments of the gut.
Some chemokines were expressed throughout the intestine (CCL28, CCL6, CXCL16,
and CX3CL1), whereas others were expressed preferentially in the small ...
Related articles - All 2 versions

Evidence for an enhanced adhesion of DC to fibronectin and a role of CCL19 and CCL21 in …


G Bouma, JMC Coppens, S Mourits, T Nikolic … - European journal of immunology, 2005 - interscience.wiley.com
The non-obese diabetic (NOD) mouse is a widely used animal model for the study
of human diabetes. The lymphocytic (peri-)insulitis is preceded by an early
accumulation of dendritic cells (DC) around the islets of Langerhans. This ...
Cited by 12 - Related articles - BL Direct - All 3 versions

Toll-like receptor signaling in small intestinal epithelium promotes B-cell recruitment and …

- nih.gov
L Shang, M Fukata, N Thirunarayanan, AP … - Gastroenterology, 2008 - Elsevier
Background & Aims: Several lines of evidence support a role for Toll-like
receptor (TLR) signaling to protect the intestine from pathogenic infection. We
hypothesized that TLR signaling at the level of the intestinal epithelium ...
Cited by 8 - Related articles - All 3 versions

Dissecting genetic control of autoimmunity in NOD congenic mice


WM Ridgway - Immunologic research, 2006 - Springer
My lab investigates genetic control of autoimmune disease and autoimmune
phenotypes using a series of nonobese diabetic (NOD) congenic mice. NOD congenic
mice have regions from B6/B10 introgressed onto the NOD genetic background, ...
Cited by 1 - Related articles - BL Direct - All 5 versions


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