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Scholar Results 1 - 10 of about 101 related to Simon: Murine antithymocyte globulin therapy alters disease progression in NOD mice by a.... (0.10 sec) 

Murine antithymocyte globulin therapy alters disease progression in NOD mice by a time- …

- diabetesjournals.org
G Simon, M Parker, V Ramiya, C Wasserfall, … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—We observed that mATG attenuates type 1 diabetes development in an
age-dependent fashion, only proving efficacious at disease onset or in the late
pre-diabetic phase (12 weeks of age). When provided at 12 weeks of age, ...
Cited by 10 - Related articles - BL Direct - All 5 versions

Characterization of in vitro antimurine thymocyte globulin-induced regulatory T cells that …

- hematologylibrary.org
MC Ruzek, JS Waire, D Hopkins, G LaCorcia, J … - Blood, 2008 - bloodjournal.hematologylibrary.org
Antithymocyte/antilymphocyte globulins are polyclonal antihuman T-cell
antibodies used clinically to treat acute transplant rejection. These reagents
deplete T cells, but a rabbit antihuman thymocyte globulin has also been ...
Cited by 8 - Related articles - BL Direct - All 2 versions

Generation, homeostasis, and regulation of memory T cells in transplantation

- turkiyeklinikleri.com [PDF] 
AL Tang, DL Farber - Current Opinion in Organ Transplantation, 2007 - journals.lww.com
Recent findings: Memory T cells are generated against alloantigens via
homologous and cross-reactive priming, and recent studies demonstrate that
T-cell depletion can also paradoxically result in memory generation. While ...
Cited by 2 - Related articles - BL Direct - All 7 versions

An antibody combination that targets activated T cells extends graft survival in sensitized …


RE Greenlaw, NJ Gardner, CA Farrar, H … - American Journal of Transplantation, 2008 - interscience.wiley.com
Memory T cells are the very essence of adaptive immunity with their rapid and
efficient response to antigen rechallenge and long-term persistence. However, it
is becoming increasingly evident that when primed with self or transplanted ...
Cited by 2 - Related articles - All 3 versions

Rational development of antigen-specific therapies for type 1 diabetes


G Fousteri, D Bresson, M von Herrath - Advances in experimental medicine and biology, 2007 - Springer
Abstract. Administration of autoantigens, especially via the mucosal route, can
induce toler- ance under certain circumstances. In autoimmune diabetes, mucosal
vaccination with autoan- tigens was frequently effective in restoring ...
Cited by 3 - Related articles - BL Direct - All 5 versions

Staying alive-naïve CD4 T cell homeostasis


JF Purton, J Sprent, CD Surh - European Journal of Immunology - interscience.wiley.com
The immune system must maintain a broad repertoire of naïve T cells in order to
respond to the diverse range of pathogens that it will encounter over the course
of a lifetime. Although it is known that contact with IL-7 is crucial for ...
Cited by 4 - Related articles - BL Direct - All 4 versions

Management of patients receiving antithymocyte globulin for aplastic anemia and …


MF Bevans, RA Shalabi - Clinical Journal of Oncology Nursing, 2004 - Onc Nurs Society
Antithymocyte globulin (ATG) is used commonly in pa- tients with severe aplastic
anemia and those undergoing renal transplant. Its utility also is being explored
in the treatment of myelodysplastic syndrome, conditioning regi- mens for ...
Cited by 5 - Related articles - BL Direct - All 2 versions

Antithymocyte globulin for prevention of graft-versus-host disease


A Bacigalupo - Current opinion in hematology, 2005 - journals.lww.com
Recent findings: The review shows that antithymocyte globulin is used frequently
in Europe in the setting of unrelated or family mismatched donor transplants.
This may not be the case for American centers, reluctant to introduce ...
Cited by 14 - Related articles - BL Direct - All 4 versions

Generation and functional capacity of polyclonal alloantigen-specific memory CD4 T cells.


AL Tang, AW Bingaman, EA Kadavil, DB … - American Journal of Transplantation, 2006 - pt.wkhealth.com
Cited by 8 - Related articles - BL Direct - All 8 versions

B cell depletion: a novel therapy for autoimmune diabetes?

- nih.gov [PDF] 
H Bour-Jordan, JA Bluestone - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig
Autoimmune diabetes is believed to be mediated primarily by T cells. However, B
cells have been implicated in the pathogenesis of the disease in NOD mice.
Although preclinical studies have been limited by the absence of anti-CD20 ...
Cited by 9 - Related articles - BL Direct - All 5 versions


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