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In vivo effects of insulin and free fatty acids on matrix metalloproteinases in rat aorta

- diabetesjournals.org
G Boden, W Song, L Pashko, K Kresge - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—Hyperinsulinemia increased MMP-2 (∼6-fold), MMP-9 (∼13-fold),
membrane type 1-MMP (MT1-MMP; ∼8-fold) (all Western blots), and gelatinolytic
activity (zymography) of MMP-2 (2-fold), while not affecting TIMP-1 and ...
Cited by 8 - Related articles - BL Direct - All 3 versions

Effects of insulin and free fatty acids on matrix metalloproteinases


G Boden, WW Song - Current Diabetes Reports, 2008 - Springer
To investigate if increased activation of matrix metal- loproteinases (MMPs) may
contribute to the large cardiovascular risk associated with obesity-related
insulin resistance, we examined the effects of physiologi- cally elevated ...
Cited by 4 - Related articles - All 2 versions

Insulin increases gelatinase activity in rat glomerular mesangial cells via ERK-and PI-3 …


MPS Lee, G Sweeney - Diabetes Obesity and Metabolism, 2006 - interscience.wiley.com
Diabetic nephropathy is associated with increased accumulation of the
extracellular matrix (ECM) in the kidney, which ultimately leads to kidney
failure. This may occur due to excessive synthesis of ECM components or ...
Cited by 4 - Related articles - BL Direct - All 4 versions

Insulin facilitates monocyte migration: a possible link to tissue inflammation in insulin- …


K Kappert, H Meyborg, M Clemenz, K Graf, E … - Biochemical and Biophysical Research …, 2008 - Elsevier
Mononuclear cells (MNCs) are the primary cell type involved in the
pro-inflammatory state of obesity-linked insulin-resistance, and
atherosclerosis. Increased serum levels of MMP-9 are reported in insulin- ...
Cited by 6 - Related articles - All 4 versions

Effects of hyperinsulinemia on hepatic metalloproteinases and their tissue inhibitors

- physiology.org
G Boden, W Song, K Kresge, M Mozzoli, P … - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc
To gain insight into the pathogenesis of hepatic fibrosis related to insulin
resistance, we have examined the effects of euglycemic hyperinsulinemia on three
matrix metalloproteinases (MMP-2, MMP-9, and MT1-MMP) and on two major ...
Related articles - All 5 versions

The 6th Annual World Congress on the Insulin Resistance Syndrome


ZT Bloomgarden - Diabetes care, 2009 - Am Diabetes Assoc
Gary Lewis (Toronto, Canada) discussed the effect of prolonged free fatty acid
(FFA) elevation on pancreatic β-cell function. FFAs are essential for
maintenance of basal insulin secretion, and acute FFA elevation increases ...
Related articles - All 4 versions

Characterization of Matrix Metalloproteinase-2 and-9 and their inhibitors in equine granulosa …


DR Sessions, MM Vick, BP Fitzgerald - Journal of Animal Science, 2009 - Am Soc Animal Sci
Page 1. DR Sessions, MM Vick and BP Fitzgerald in vitro and in vivo granulosa
cells Characterization of Matrix Metalloproteinase-2 ...
Related articles - All 2 versions

InsulinBlood Cardioplegia Decreases Matrix Metalloproteinase Activity in Ischaemia- …


H Catalyurek, G Oktay, M Guzeloglu, Z Cavdar, … - The Journal of International Medical Research, 2008 - ingentaconnect.com
Reperfusion of myocardium during coronary bypass activates matrix
metalloproteinases (MMPs) with changes occurring in the levels of tissue
inhibitors of metalloproteinases (TIMPs) in the myocardium. This study ...
Cited by 2 - Related articles - BL Direct - All 2 versions

[CITATION] Insulin resistance and adiponectin levels in Behçet's syndrome.


A Oguz, EG Dogan, M Uzunlulu, FM Oguz - Clinical and experimental rheumatology - ncbi.nlm.nih.gov
1: Clin Exp Rheumatol. 2007 Jul-Aug;25(4 Suppl 45):S118-9. Insulin resistance
and adiponectin levels in Behçet's syndrome. Oguz ...
Cited by 1 - Related articles - BL Direct

[CITATION] The relationship between steroidogenesis and tissue remodeling enzymes in ovulation in …


AL Desvousges, A EISELE, MB Porter, DC … - Theriogenology, 2002 - cat.inist.fr
The relationship between steroidogenesis and tissue remodeling enzymes in
ovulation in cycling pony mares. AL DESVOUSGES, A EISELE ...
Cited by 2 - Related articles


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