J Nakae, Y Cao, M Oki, Y Orba, H Sawa, H Kiyonari, K … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—The aP 2 -FLAG- 256 mice showed improved glucose tolerance and insulin sensitivity
accompanied with smaller-sized adipocytes and increased adiponectin (adipoq) and Glut 4
(Slc2a4) and decreased tumor necrosis factor (Tnf) and chemokine (CC motif) receptor 2 ( ... Cited by 13 - Related articles - BL Direct - All 4 versions
I Gerin, GT Bommer, ME Lidell, A Cederberg, S … - Journal of Biological …, 2009 - ASBMB In this study, we explore the effects of several FOX and mutant FOX transcription factors on adipocyte
determination, differentiation, and metabolism. In addition to Foxc2 and Foxo1, we report that
Foxf2, Foxp1, and Foxa1 are other members of the Fox family that show regulated ... Cited by 1 - Related articles - All 3 versions
… A Fukushima, S Viengchareun, M Lombes … - American Journal of …, 2009 - Am Physiological Soc Salt-inducible kinase 2 (SIK2) is expressed abundantly in adipose tissues and represses
cAMP-response element-binding protein (CREB)-mediated gene expression by phosphorylating
the coactivator transducer of regulated CREB activity (TORC2). Phosphorylation at Ser ... Related articles - All 3 versions
- ►wdc-jp.com [PDF] Y Johmura, K Watanabe, K Kishimoto, T Ueda, S … - … & Pharmaceutical Bulletin, 2009 - J-STAGE Obesity is a major risk factor for type 2 diabetes, hyper- tension, hyperlipidemia, and also
arteriosclerosis.1) The inci- dence of obesity has been increasing worldwide, and new ap- proaches
to treatment are desired. The increase in adipose tissue mass in obese individuals is ... Related articles - All 4 versions
E Rosen, J Eguchi, Z Xu - Expert Opin. Ther. Targets, 2009 - informahealthcare.com The global burden of metabolic disease demands that we develop new therapeutic
strategies. Many of these approaches may center on manipulating the behavior of
adipocytes, which contribute directly and indirectly to a host of disease processes ... Related articles - All 6 versions
M Artal-Sanz, N Tavernarakis - Nature, 2009 - imbb.forth.gr Marked alterations in cellular energy metabolism are a universal hallmark of the ageing
process1. The biogenesis and function of mitochondria, the energy-generating organelles in
eukaryotic cells, are primary longevity determinants. Genetic or pharmacological ... Related articles - View as HTML - All 5 versions
- ►endojournals.org AL Wu, JH Kim, C Zhang, TG Unterman, J Chen - Endocrinology, 2008 - Endocrine Soc The forkhead transcription factor forkhead box protein O1 (FoxO1), a downstream target of phosphatidylinositol
3-kinase/Akt signaling, has been reported to suppress skeletal myocyte differentiation, but the
mechanism by which FoxO1 regulates myogenesis is not fully understood. We have ... Cited by 14 - Related articles - BL Direct - All 5 versions
T Kitamura, KY Ido - Endocrine journal, 2007 - ncbi.nlm.nih.gov Forkhead transcription factors of the FoxO family have important roles in cellular
proliferation, apoptosis, differentiation and stress resistance. FoxO proteins also play important
roles in metabolism of complex organisms. FoxO1 regulates glucose and lipid ... Cited by 12 - Related articles - BL Direct
- ►cell.com XC Dong, KD Copps, S Guo, Y Li, R Kollipara, RA … - Cell metabolism, 2008 - Elsevier The forkhead transcription factor Foxo1 regulates expression of genes involved in stress resistance
and metabolism. To assess the contribution of Foxo1 to metabolic dysregulation during hepatic
insulin resistance, we disrupted Foxo1 expression in the liver of mice lacking hepatic Irs1 ... Cited by 12 - Related articles - All 11 versions
