A Shapiro, M Matheny, Y Zhang, N Tümer, KY Cheng, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—In standard diet–raised rats, either wheel running or leptin reduced the trajectory
of weight gain, and the combined effect of both treatments was additive. In high-fat–raised
leptin-resistant rats, leptin overexpression first transiently reduced weight gain but then ... Cited by 10 - Related articles - BL Direct - All 4 versions
[CITATION] Does gut hormone PYY (3-36) decrease food intake in rodents
PJ Scarpace, M Matheny, N Tümer, KY Cheng, Y … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: Leptin resistance is generally considered a consequence of
obesity. We postulated that leptin resistance is associated with diminished hypotha- lamic leptin
signalling capacity and that leptin resistance is causal to obesity. We assessed maximal ... Cited by 38 - Related articles - All 4 versions
- ►physiology.org A Shapiro, W Mu, C Roncal, KY Cheng, … - American Journal of …, 2008 - Am Physiological Soc It has been suggested that increased fructose intake is associated with obesity. We hypothesized
that chronic fructose consumption causes leptin resistance, which subsequently may promote
the development of obesity in response to a high-fat diet. Sprague-Dawley rats were fed a ... Cited by 14 - Related articles - All 3 versions
- ►endojournals.org J Wilsey, MK Matheny, PJ Scarpace - Endocrinology, 2006 - Endocrine Soc Recently, vanadium has been shown to enhance leptin signal transduction in vitro. We hypothesized
that chronic oral administration of an organic vanadium complex would enhance both leptin signaling
and physiological responsiveness in vivo. Three-month-old F344 x Brown Norway male ... Cited by 6 - Related articles - BL Direct - All 5 versions
PJ Scarpace, Y Zhang - Front Biosci, 2007 - bioscience.org Leptin is an adipocyte-derived, satiety-regulating hormone that acts within the hypothalamus
and other brain sites. Obese humans and animals are largely resistant to central actions of
leptin. Rising leptin levels associated with progressing obesity are generally regarded as ... Cited by 25 - Related articles - View as HTML - All 2 versions
- ►aspetjournals.org PJ Scarpace, M Matheny, Y Zhang, KY Cheng, N … - Journal of Pharmacology …, 2007 - ASPET Leptin-resistant rats have reduced leptin receptors and signaling and are refractory to exogenous
leptin. However, it is unclear how leptin-mediated hypothalamic signal transducer and activator
of transcription 3 (STAT3) signaling relates to the loss of physiological responsiveness. ... Cited by 9 - Related articles - All 4 versions
PK Chelikani, AC Haver, RD Reidelberger - Peptides, 2006 - Elsevier We used a conditioned taste aversion test to assess whether PYY(3-36) reduces food intake
by producing malaise. Two-hour IV infusion of PYY(3-36) (8, 15, and 30 pmol/kg/min) at dark
onset in non-food-deprived rats produced a dose-dependent inhibition of feeding and a ... Cited by 9 - Related articles - All 4 versions
Y Nie, C Viola, C Bieniossek, S Trowitzsch, LS … - Current …, 2009 - ingentaconnect.com Abstract: We are witnessing tremendous advances in our understanding of the organization of
life. Complete genomes are being deciphered with ever increasing speed and accuracy, thereby
setting the stage for addressing the entire gene product repertoire of cells, towards ... Related articles
S Unniappan, TJ Kieffer - American Journal of Physiology. …, 2008 - pubmedcentral.nih.gov Acute administration of peptide YY(3-36) [PYY(3-36)] results in a reduction in food intake in several
different vertebrates. However, long-term continuous administration of PYY(3-36) causes only
a transient reduction in food intake, thus potentially limiting its therapeutic efficacy. We ... Related articles - All 2 versions
