K Brands, E Colvin, LJ Williams, R Wang, RB Lock, BE … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—The use of human fetal pancreatic tissue may provide a potential source of
transplantable β-cells as a therapy for type 1 diabetes. Human fetal pancreas has a remarkable
capacity to grow and differentiate ... Cited by 7 - Related articles - BL Direct - All 4 versions
M KING, T Pearson, LD Shultz, J Leif, R … - ANNALS-NEW …, 2007 - interscience.wiley.com Abstract : The use of "humanized" mice represents an appealing translational model for studies of
the pathogenesis of immune-mediated diseases and for the evaluation of potential therapeutics. The
utility of humanized mice depends ... Cited by 5 - Related articles - BL Direct - All 8 versions
G Fousteri, M von Herrath - Diabetes, 2008 - Am Diabetes Assoc Type 1 diabetes results from immune-mediated destruction of insulin-producing β-cells of the
pancreas. The disease manifests itself symptomatically when the resident β-cells become unable to
maintain normoglycemia. In human ... Related articles - BL Direct - All 3 versions
G Fousteri, M von Herrath - DIABETES, 2008 - Am Diabetes Assoc T ype 1 diabetes results from immune-mediated destruction of insulin-producing -cells of the
pancreas. The disease manifests itself symptom- atically when the resident -cells become unable to
maintain normoglycemia. In human ... Related articles
BE Tuch, K Kannangara - Drug Discovery Today: Therapeutic Strategies, 2009 - Elsevier Replacing the 350 million β cells destroyed in people with type 1 diabetes has traditionally been
sought by transplanting human pancreatic tissue obtained after death. Alternative sources of
exogenous surrogate β cells being ... Related articles
MF Lopes, AMS Cabrita, JAB Patrício - Pediatric surgery international, 2000 - Springer Abstract Adult intestinal allografts have demonstrated high immunogenicity in human transplantation,
making the search for new and more favorable grafts an actual problem. Accepting that fetal and
newborn immune systems are ... Cited by 8 - Related articles - BL Direct - All 3 versions
Z Si, BE Tuch, DA Walsh - Cells Tissues Organs, 2000 - content.karger.com Only a small component of human fetal pancreas consists of cells, and yet this tissue is capable of
normalizing the blood glucose levels of diabetic recipients when transplanted. The time taken to
achieve this goal is several ... Cited by 9 - Related articles - BL Direct - All 4 versions
LD Shultz, T Pearson, M KING, L GIASSI, … - ANNALS-NEW …, 2007 - interscience.wiley.com Abstract : There are many rodent models of autoimmune diabetes that have been used to study the
pathogenesis of human type 1 diabetes (T1D), including the non-obese diabetic (NOD) mouse, the
biobreeding (BB) rat, and the ... Cited by 9 - Related articles - BL Direct - All 7 versions
M Cananzi, A Atala, P De Coppi - Reproductive BioMedicine Online, 2009 - ingentaconnect.com Paolo De Coppi is a Clinical Senior Lecturer and Consultant in Paediatric Surgery at the UCL
Institute of Child Health and Great Ormond Street Hospital, London, UK. His clinical training and
PhD in tissue engineering and cell ... Cited by 2 - Related articles - All 2 versions
- ►diabetesjournals.org N Fiaschi-Taesch, TA Bigatel, B Sicari, KK Takane, F … - Diabetes, 2009 - Am Diabetes Assoc OBJECTIVES To comprehensively inventory the proteins that control the G1/S cell cycle checkpoint in
the human islet and compare them with those in the murine islet, to determine whether these might
therapeutically enhance human ... Cited by 1 - Related articles - All 3 versions
