N Cheurfa, D Dubois-Laforgue, DAF Ferrarezi, AF Reis, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—We observed an inverse association of the A allele with incident cases of CAD in
a dominant model (hazard risk 0.88 [95% CI 0.80–0.96]; P = 0.006). Similar results were observed
for baseline cases of CAD. Stratification by sex confirmed an allelic association with CAD ... Cited by 8 - Related articles - BL Direct - All 4 versions
YH Hsu, T Niu, Y Song, L Tinker, LH Kuller, S Liu - Diabetes, 2008 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—We conducted a comprehensive assessment of common
single nucleotide polymorphisms (SNPs) at the 70-kb UCP2-UCP3 gene cluster in relation to
type 2 diabetes risk in a prospective, case-control study nested in the Women's Health ... Cited by 5 - Related articles - BL Direct - All 4 versions
T Hamada, K Kotani, S Fujiwara, Y Sano, M … - Metabolism-Clinical …, 2008 - 万方数据资源系统 Uncoupling protein 3 (UCP3) is considered to be associated with obesity, given its function in
the regulation of energy and lipid metabolism. An increased body mass index (BMI) and a decreased
level of high-density lipoprotein cholesterol (HDL-C) are risk factors for cardiovascular ... Cited by 8 - Related articles - All 13 versions
JW Stephens, SS Dhamrait, AR Mani, J Acharya, K … - Nutrition, Metabolism and …, 2008 - Elsevier Amongst 453 Caucasian diabetic men there was a significant interaction (p = 0.001) between
genotype and smoking in determining plasma Total AntiOxidant Status (TAOS). Current smokers
with the −866AA genotype had the lowest TAOS (indicating higher oxidative stress) of all ... Cited by 6 - Related articles - All 7 versions
- ►unav.es [PDF] MC Ochoa, JL Santos, C Azcona, MJ Moreno- … - Molecular Genetics and …, 2007 - Elsevier A number of studies have yielded controversial results on the association between polymorphisms
in UCP2 and UCP3 genes with obesity and its comorbidities. The discrepancy among studies
might be partially explained by the lack of consideration of the effect of adjacent loci in the ... Cited by 8 - Related articles - All 3 versions
AF Reis, D Dubois-Laforgue, C Bellanné-Chantelot, … - Molecular Genetics and …, 2004 - Elsevier AG/A single nucleotide polymorphism (SNP) in the position −866 of the UCP2 promoter modulates
UCP2 expression in adipose tissue and pancreatic β-cell, and is associated with variations of
body mass index (BMI) and insulin secretion in nondiabetic subjects. We investigated ... Cited by 16 - Related articles - All 3 versions
DA de Luis, R Aller, O Izaola, M González Sagrado, … - Ann Nutr Metab, 2007 - content.karger.com Background and Aims: Some studies have pointed to a role of UCP3 in the regulation of
whole-body energy homeostasis and regulation of fat distribution. The aim of our study was to
investigate the influence of -55CT polymorphism of UCP3 gene on fat distribution and ... Cited by 5 - Related articles - BL Direct - All 4 versions
Y Yoon, BL Park, MH Cha, KS Kim, HS Cheong, YH … - … and biophysical research …, 2007 - Elsevier The uncoupling protein (UCP) family has been suggested as a possible determinant affecting
obesity risk given their function in the regulation of energy metabolism. In an effort to elucidate
the effects of UCP family polymorphisms on obesity phenotypes, we genotyped 10 ... Cited by 13 - Related articles - All 5 versions
MH Cha, IC Kim, KS Kim, BK Kang, SM Choi, Y Yoon - Metabolism, 2007 - Elsevier Decreased serum high-density lipoprotein (HDL-C) cholesterol is a major risk factor for atherosclerosis
and vascular disease. In this study, we assessed the association of 10 uncoupling protein
(UCP) 2 and UCP3 polymorphisms with serum HDL cholesterol levels and atherogenic ... Cited by 7 - Related articles - All 8 versions
R Rosmond, C Bouchard, P Björntorp - BBA-Molecular Basis of Disease, 2002 - Elsevier The uncoupling protein (UCP) 2 gene is expressed in adipose tissues and skeletal muscles,
which are important sites for variations in energy expenditure. The objective of the current study
was to examine the potential impact of a C→T substitution in exon 4, resulting in an ... Cited by 8 - Related articles - All 5 versions
