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Scholar Results 1 - 10 of about 101 related to Niehof: HNF4α and the Ca-Channel TRPC1 Are Novel Disease Candidate Genes in Diabetic Nephropathy. (0.08 sec) 

HNF4α and the Ca-Channel TRPC1 Are Novel Disease Candidate Genes in Diabetic …


M Niehof, J Borlak - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—We identified the calcium-permeable nonselective transient receptor
potential cation channel, subfamily C, member 1 (TRPC1) as a novel HNF4α gene
target. Strikingly, TRPC1 is localized on human chromosome 3q22-24, ie, a ...
Cited by 6 - Related articles - BL Direct - All 3 versions

Expression of HNF4alpha in the human and rat choroid plexus–Implications for drug …


M Niehof, J Borlak - BMC Molecular Biology, 2009 - pubmedcentral.nih.gov
The choroid plexus consists of highly differentiated epithelium and functions as
a barrier at the interface of the blood-cerebrospinal-fluid (CSF). This tissue
may therefore determine the bioavailability and transport of drugs to the ...
Related articles - All 5 versions

HNF4alpha and HNF1alpha Dysfunction as a Molecular Rational for Cyclosporine Induced …


J Borlak, M Niehof - PLoS ONE, 2009 - pubmedcentral.nih.gov
Posttransplantation diabetes mellitus (PTDM) is a frequent complication in
immunosuppressive therapy. To better understand the molecular events associated
with PTDM we investigated the effect of cyclosporine on expression and ...
Related articles - All 4 versions

RSK4 and PAK5 are novel candidate genes in diabetic rat kidney and brain

- aspetjournals.org
M Niehof, J Borlak - Molecular pharmacology, 2005 - ASPET
The orphan hepatic nuclear factor (HNF) HNF4 is of pivotal importance for liver
development and hepatocellular differentiation and plays an essential role in a
regulatory circuitry to control a wide range of metabolic processes. It ...
Cited by 14 - Related articles - All 6 versions

Autoantibodies against TRPC3 and ryanodine receptor in myasthenia gravis


M Takamori - Journal of neuroimmunology, 2008 - Elsevier
The transient receptor potential canonical type-3 (TRPC3, receptor- and
store-operated Ca 2+ influx channel) participates in skeletal muscle
contraction; its functional interactions with ryanodine receptor-1 (RyR1) ...
Cited by 1 - Related articles - All 16 versions

Evaluation of Genetic Association and Expression Reduction of TRPC1 in the Development …

- nih.gov
D Zhang, BI Freedman, M Flekac, E Santos, … - American journal of nephrology, 2008 - content.karger.com
Background/Aims: The TRPC1 gene on chromosome 3q22-24 resides within the linkage
region for diabetic nephropathy (DN) in type 1 (T1D) and type 2 diabetes
mellitus (T2D). A recent study has demonstrated that TRPC1 expression is ...
Cited by 2 - Related articles - All 5 versions

Molecular characterization of lung dysplasia induced by c-raf-1


A Rohrbeck, VS Müller, J Borlak - PloS one, 2009 - pubmedcentral.nih.gov
We employed laser microdissection to harvest c-Raf1- induced dysplastic as
opposed to transgenic but otherwise morphologically unaltered epithelium and
compared findings to non-transgenic lung. We then employed microarrays to ...
Cited by 1 - Related articles - All 4 versions

Cyclic stretch decreases TRPC4 protein and capacitative calcium entry in rat vascular …


SH Lindsey, RM Tribe, E Songu-Mize - Life sciences, 2008 - ncbi.nlm.nih.gov
We investigated whether cyclic stretch affects TRPC4 or TRPC6 expression and
calcium mobilization in cultured vascular smooth muscle cells. In aortic and
mesenteric smooth muscle cells isolated from male Sprague-Dawley rats, ...
Cited by 1 - Related articles - All 2 versions

Interaction of hepatocyte nuclear factors in transcriptional regulation of tissue specific …


I Qadri, LJ Hu, M Iwahashi, S Al-Zuabi, LC … - Toxicology and Applied Pharmacology, 2009 - Elsevier
MRP2 promoter-LUC constructs were highly expressed in liver cell lines compared
to non-liver cells. The region extending from − 3 to+ 458 bp of MRP2 promoter
starting from AUG contained the potential binding sites for CAAATT box ...
Cited by 2 - Related articles - All 3 versions

EPS15R, TASP1, and PRPF3 Are Novel Disease Candidate Genes Targeted by HNF4α Splice …


M Niehof, J Borlak - Gastroenterology, 2008 - Elsevier
Background & Aims: The orphan nuclear receptor HNF4α is a member of the hepatic
transcription factor network. This protein plays a pivotal role in liver
development and hepatocellular differentiation. Nine splice variants have ...
Cited by 1 - Related articles - All 2 versions


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