- ►diabetesjournals.org E Orilieri, G Cappellano, R Clementi, A Cometa, M … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—In both cohorts, allelic frequency of N252S was significantly higher in patients than
in control subjects (combined cohorts: 1.5 vs. 0.4%; odds ratio 6.68 [95% CI 1.83–7.48]). Sequencing
of the entire coding region detected one novel mutation in one patient, causing a P477A ... Cited by 3 - Related articles - BL Direct - All 4 versions
PA Mehta, SM Davies, A Kumar, M Devidas, S Lee, T … - Leukemia, 2006 - nature.com Perforin plays a key role in the cytotoxicity of natural killer and cytotoxic T cells. Genetic mutations
in the perforin gene (PRF1) give rise to approximately 30% cases of familial hemophagocytic
lymphohistiocytosis. A frequent polymorphism, A91V (C to T transition at position 272), ... Cited by 7 - Related articles - BL Direct - All 4 versions
S D'Alfonso, E Bolognesi, FR Guerini, N Barizzone, S … - Genes and Immunity, 2007 - nature.com Several studies suggest that the histocompatibility complex (HLA) class I region harbours genes
modulating multiple sclerosis (MS) susceptibility independently from the effect of class II
alleles. A candidate gene in this region is MOG, encoding the myelin oligodendrocyte ... Cited by 4 - Related articles - BL Direct - All 3 versions
R Goertsches, SE Baranzini, C Morcillo, C Nos, M … - Multiple …, 2008 - msj.sagepub.com A recent association study has provided evidence that chromosome 10q22.1 may contain candidate
genes for multiple sclerosis (MS). We analysed two intronic and a non-synonymous single nucleotide
polymorphism (SNP) of the C10orf27 gene in 571 patients with MS (relapsing remitting ... Cited by 3 - Related articles - BL Direct - All 3 versions
J Chen, JS Brandt, FM Ellison, RT Calado, NS … - Experimental hematology, 2005 - Elsevier Donor lymphocytes infiltrated host BM within 3–7 days and expanded significantly between 7
and 10 days, concurrent with the development of leukopenia, thrombocytopenia, and marrow
hypoplasia. BM cells from mice at 7, 10, and 14 days after B6-LN cell infusion were ... Cited by 3 - Related articles - All 8 versions
G Cappellano, E Orilieri, C Comi, A Chiocchetti, S … - Genes and Immunity, 2008 - nature.com Perforin is involved in cell-mediated cytotoxicity and mutations of its gene (PRF1) cause familial
hemophagocytic lymphohistiocytosis (FLH2). PRF1 sequencing in 190 patients with multiple
sclerosis and 268 controls detected two FLH2-associated variations (A91V, N252S) in ... Cited by 3 - Related articles - All 3 versions
MW Su, S Pyarajan, JH Chang, CL Yu, YJ Jin, … - Eur. J. …, 2004 - interscience.wiley.com CD8 + CTL mediate the destruction of cells displaying foreign peptides in association with class
I MHC molecules. Since CD8 + CTL themselves express class I MHC molecules, a phenomenon
known as fratricide can be elicited by T cells presenting antigens to other CTL. To gain ... Cited by 9 - Related articles - BL Direct - All 4 versions
S Cannella, A Santoro, G Bruno, M Pillon, L … - CA A Cancer Journal … - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 4 - Related articles - BL Direct - All 3 versions
- ►bloodjournal.org R Clementi, A Chiocchetti, G Cappellano, E Cerutti, M … - Blood, 2006 - Am Soc Hematology From the Pediatric Haematology-Oncology, Istituto di Ricovero e Cura a Carattere Scientifico
(IRCCS) Policlinico San Matteo, University of Pavia, Pavia, Italy; Interdisciplinary Research Center
of Autoimmune Diseases (IRCAD) and Department of Medical Sciences, "A. Avogadro" ... Cited by 17 - Related articles - BL Direct - All 6 versions
L Marks, RB Levy - Transplantation, 2004 - journals.lww.com The mechanisms of T-cell regulation are difficult to elucidate because of their complexity and
the numer- ous subcategories of cell populations. There are two fundamental approaches to
address this conundrum. First, it is possible to use a purified cell population and submit ... Cited by 6 - Related articles - BL Direct - All 3 versions
