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Scholar Results 1 - 10 of about 101 related to Palmer: Quantitative trait analysis of type 2 diabetes susceptibility loci identified from.... (0.12 sec) 

Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole …

- diabetesjournals.org [PDF] 
ND Palmer, MO Goodarzi, CD Langefeld, J Ziegler, JM … - Diabetes, 2008 - Am Diabetes Assoc
Nicholette D. Palmer, 1,2 Mark O. Goodarzi, 3 Carl D. Langefeld, 4 Julie Ziegler, 4 Jill M.
Norris, 5 ... Steven M. Haffner, 6 Michael Bryer-Ash, 7,8 Richard N. Bergman, 9 Lynne E.
Wagenknecht, 4 ... Kent D. Taylor, 3 Jerome I. Rotter, 3 and Donald W. Bowden 1,2,10
Cited by 26 - Related articles - BL Direct - All 4 versions

The common SLC30A8 Arg325Trp variant is associated with reduced first-phase …


TW Boesgaard, J Žilinskaitė, M Vänttinen, M Laakso, … - Diabetologia, 2008 - Springer
Abstract Aims/hypothesis A recent genome-wide association study identified the SLC30A8 rs13266634
polymorphism encoding an Arg325Trp polymorphism in the zinc transporter protein member
8 (ZnT-8) to be associated with type 2 diabetes. Here, ... Keywords Beta cell dysfunction . ...
Cited by 20 - Related articles - BL Direct - All 3 versions

A candidate type 2 diabetes polymorphism near the HHEX locus affects acute …

- diabetesjournals.org
H Staiger, A Stančáková, J Zilinskaite, M Vänttinen, T … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—SNPs rs1111875 and rs7923837 were not associated with anthropometric data
(age, weight, height, BMI, body fat, and waist and hip circumference). After adjustment for
center, family relationship, sex, age, and BMI, both SNPs were also not associated with ...
Cited by 17 - Related articles - BL Direct - All 4 versions

Polymorphisms within novel risk loci for type 2 diabetes determine β-cell function


H Staiger, F Machicao, N Stefan, O Tschritter, C … - PLoS One, 2007 - pubmedcentral.nih.gov
Background. Type 2 diabetes arises when insulin resistance-induced compensatory insulin secretion
exhausts. Insulin resistance and/or b-cell dysfunction result from the interaction of environmental
factors (high-caloric diet and reduced physical activity) with a predisposing polygenic ...
Cited by 47 - Related articles - All 5 versions

Genetic analysis of recently identified type 2 diabetes loci in 1,638 unselected …


JK Hertel, S Johansson, H Raeder, K Midthjell, V … - Diabetologia, 2008 - Springer
Abstract Aims/hypothesis Recent genome-wide association studies performed in selected patients
and control participants have provided strong support for several new type 2 diabetes susceptibility
loci. To get a better estimation of the true risk conferred by these novel loci, we tested a ...
Cited by 13 - Related articles - BL Direct - All 2 versions

Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with …


K Kirchhoff, F Machicao, A Haupt, SA Schäfer, O … - Diabetologia, 2008 - Springer
Abstract Aims/hypothesis Variation within six novel genetic loci has been reported to confer risk
of type 2 diabetes and may be associated with beta cell dysfunction. We investigated whether
these polymorphisms are also associated with impaired proinsulin to insulin conversion. ...
Cited by 38 - Related articles - BL Direct - All 3 versions

Zinc transporter-8 gene (SLC30A8) is associated with type 2 diabetes in Chinese

- endojournals.org
J Xiang, XY Li, M Xu, J Hong, Y Huang, JR Tan, … - Journal of Clinical …, 2008 - Endocrine Soc
Results: A significant association for SNP rs13266634 was observed between patients with type
2 diabetes and NGT controls (P = 0.016). The association was also observed between combined
type 2 diabetes/IGR and NGT subjects (P = 0.002). The adjusted odds ratios for ...
Cited by 11 - Related articles - All 3 versions

Replication of genome-wide association studies of type 2 diabetes susceptibility in …

- endojournals.org
Y Horikawa, K Miyake, K Yasuda, M Enya, Y … - Journal of Clinical …, 2008 - Endocrine Soc
Results: A total of 15 SNPs were genotyped. Eight SNPs in five loci were found to be associated
with type 2 diabetes: rs3802177 [odds ratio (OR) = 1.16 (95% confidence interval (CI)
1.05–1.27); P = 4.5 x 10 –3 ] in SLC30A8; rs1111875 [OR = 1.27 (95% CI 1.14–1.40); P = ...
Cited by 20 - Related articles - All 3 versions

Polymorphisms in the IDE-KIF11-HHEX gene locus are reproducibly associated …

- endojournals.org [PDF] 
Y Furukawa, T Shimada, H Furuta, S Matsuno, … - Journal of Clinical …, 2007 - Endocrine Soc
Page 1. Polymorphisms in the IDE-KIF11-HHEX gene locus are reproducibly
associated with type 2 diabetes in a Japanese population Yasushi Furukawa 1* ,
Takeshi Shimada 1* , Hiroto Furuta 1 , Shohei Matsuno 1 , Akiko ...
Cited by 15 - Related articles - BL Direct - All 3 versions

Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE …


Y Wu, H Li, RJF Loos, Z Yu, X Ye, L Chen, A Pan, FB … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS— We confirmed the associations between type 2 diabetes and variants near CDKAL1
(odds ratio 1.49 [95% CI 1.27–1.75]; P = 8.91 × 10 −7 ) and CDKN2A/B (1.31 [1.12–1.54]; P =
1.0 × 10 −3 ). We observed significant association of SNPs in IGF2BP2 (1.17 [1.03–1.32]; ...
Cited by 28 - Related articles - All 5 versions


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